CNTA vs LGND

Comparison between Centessa Pharmaceuticals plc (CNTA, Company) and Ligand Pharmaceuticals Inc - Class B (LGND, Company).

Both CNTA and LGND are from the Healthcare sector.

5-Year PerformanceLGND has outperformed CNTA, delivering a return of +19.1% compared to +10.6%

CNTA vs LGND - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CNTA(COMPANY)	LGND(COMPANY)
Market Cap	$6.27B	$6.25B
Max Drawdown	88.19%	95.01%
Sharpe Ratio	1.84	2.86
5Y Beta	N/A	0.96
Industry	Biotechnology	Biotechnology
P/E Ratio	-23.28	39.93
Forward P/E	N/A	34.97
PEG Ratio	N/A	1.53
Dividend Yield	93.80%	N/A
5Y EPS CAGR	N/A	26.59%
Debt to Equity	22.66%	0.00%
Free Cash Flow Yield	-3.34%	1.97%
P/S Ratio	N/A	22.78
P/B Ratio	N/A	6.27

Market Cap

Winner

CNTA

$6.27B

LGND

$6.25B

Max Drawdown

Winner

CNTA

88.19%

LGND

95.01%

Sharpe Ratio

CNTA

1.84

Winner

LGND

2.86

5Y Beta

CNTA

N/A

LGND

0.96

Industry

CNTA

Biotechnology

LGND

Biotechnology

P/E Ratio

Winner

CNTA

-23.28

LGND

39.93

Forward P/E

CNTA

N/A

LGND

34.97

PEG Ratio

CNTA

N/A

LGND

1.53

Dividend Yield

CNTA

93.80%

LGND

N/A

5Y EPS CAGR

CNTA

N/A

LGND

26.59%

Debt to Equity

CNTA

22.66%

Winner

LGND

0.00%

Free Cash Flow Yield

CNTA

-3.34%

Winner

LGND

1.97%

P/S Ratio

CNTA

N/A

LGND

22.78

P/B Ratio

CNTA

N/A

LGND

6.27

CNTA vs LGND - Historical Returns

Returns include dividend reinvestment.

Period	CNTA	LGND
1 month	+1.81%	+37.29%
3 months	+43.52%	+60.10%
6 months	+57.71%	+68.09%
1 year	+201.56%	+181.15%
5 years(CAGR)	+10.58%	+19.12%
10 years(CAGR)	N/A	+10.10%
Max(CAGR)	+13.03%	+16.07%

CNTA

+1.81%

Winner

LGND

+37.29%

CNTA

+43.52%

Winner

LGND

+60.10%

CNTA

+57.71%

Winner

LGND

+68.09%

Winner

CNTA

+201.56%

LGND

+181.15%

5Y(CAGR)

CNTA

+10.58%

Winner

LGND

+19.12%

10Y(CAGR)

CNTA

N/A

LGND

+10.10%

Max(CAGR)

CNTA

+13.03%

Winner

LGND

+16.07%

CNTA vs LGND - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	CNTA	LGND
2026	+70.96%	+68.09%
2025	+42.91%	+74.39%
2024	+108.59%	+48.18%
2023	+154.31%	+8.16%
2022	-73.25%	-55.93%
2021	-48.23%	+52.82%
2020	N/A	-5.05%
2019	N/A	-23.88%
2018	N/A	-2.11%
2017	N/A	+33.59%
2016	N/A	-0.84%
2015	N/A	+101.79%
2014	N/A	+3.28%
2013	N/A	+153.86%
2012	N/A	+74.14%
2011	N/A	+32.04%
2010	N/A	+334.22%
2009	N/A	-19.63%
2008	N/A	-43.62%
2007	N/A	-41.09%
2006	N/A	-4.78%
2005	N/A	-0.45%
2004	N/A	-22.04%
2003	N/A	+168.56%
2002	N/A	-68.50%
2001	N/A	+30.18%
2000	N/A	+0.86%
1999	N/A	+52.61%

CNTA vs LGND Drawdown Comparison

The maximum drawdown for CNTA was -88.19%, occurring on Feb 16, 2023. Recovery took 1107 trading sessions.

The maximum drawdown for LGND was -93.36%, occurring on Nov 19, 2008. Recovery took 3033 trading sessions.

Rank	CNTA	LGND
#1	-88.19% Jun 17, 2021 - Nov 12, 2025	-93.36% Mar 6, 2000 - Mar 26, 2012
#2	-26.38% Dec 5, 2025 - Mar 31, 2026	-81.94% Sep 28, 2018 - Jun 18, 2026
#3	-13.54% Jun 2, 2021 - Jun 17, 2021	-46.77% Mar 18, 2014 - Apr 8, 2015
#4	-3.06% Nov 24, 2025 - Dec 4, 2025	-37.01% Mar 26, 2012 - Jul 26, 2012
#5	-2.89% Nov 18, 2025 - Nov 24, 2025	-34.19% Aug 1, 2016 - Oct 4, 2017
#6	-2.73% Nov 12, 2025 - Nov 14, 2025	-26.20% Aug 5, 2015 - Dec 16, 2015
#7	-1.10% Apr 1, 2026 - Jun 2, 2026	-23.30% Dec 17, 2015 - Apr 6, 2016
#8	-1.05% Nov 14, 2025 - Nov 18, 2025	-21.24% Oct 29, 2013 - Jan 10, 2014
#9	-0.70% Jun 2, 2026 - Jun 18, 2026	-21.19% Jul 31, 2012 - Nov 26, 2012
#10	N/A	-17.44% Mar 12, 2018 - May 15, 2018
#11	N/A	-17.40% Jul 22, 2013 - Oct 17, 2013
#12	N/A	-16.85% Dec 10, 1999 - Dec 29, 1999
#13	N/A	-16.72% Jan 24, 2000 - Feb 10, 2000
#14	N/A	-14.25% Apr 21, 2016 - Jul 20, 2016
#15	N/A	-14.12% Feb 18, 2000 - Mar 6, 2000