CNTA vs ALKS

Comparison between Centessa Pharmaceuticals plc (CNTA, Company) and Alkermes plc (ALKS, Company).

Both CNTA and ALKS are from the Healthcare sector.

5-Year PerformanceCNTA has outperformed ALKS, delivering a return of +12.9% compared to +10.7%

CNTA vs ALKS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CNTA(COMPANY)	ALKS(COMPANY)
Market Cap	$6.15B	$6.16B
Max Drawdown	88.19%	96.14%
Sharpe Ratio	1.89	0.49
5Y Beta	N/A	0.66
Industry	Biotechnology	Drug Manufacturers - Specialty & Generic
P/E Ratio	-22.85	39.87
Forward P/E	N/A	97.09
PEG Ratio	N/A	1.96
Debt to Equity	22.66%	86.23%
Free Cash Flow Yield	-3.40%	3.60%
P/S Ratio	N/A	3.94
P/B Ratio	N/A	3.52

Market Cap

CNTA

$6.15B

Winner

ALKS

$6.16B

Max Drawdown

Winner

CNTA

88.19%

ALKS

96.14%

Sharpe Ratio

Winner

CNTA

1.89

ALKS

0.49

5Y Beta

CNTA

N/A

ALKS

0.66

Industry

CNTA

Biotechnology

ALKS

Drug Manufacturers - Specialty & Generic

P/E Ratio

Winner

CNTA

-22.85

ALKS

39.87

Forward P/E

CNTA

N/A

ALKS

97.09

PEG Ratio

CNTA

N/A

ALKS

1.96

Debt to Equity

Winner

CNTA

22.66%

ALKS

86.23%

Free Cash Flow Yield

CNTA

-3.40%

Winner

ALKS

3.60%

P/S Ratio

CNTA

N/A

ALKS

3.94

P/B Ratio

CNTA

N/A

ALKS

3.52

CNTA vs ALKS - Historical Returns

Returns include dividend reinvestment.

Period	CNTA	ALKS
1 month	+0.81%	+10.23%
3 months	+62.49%	+15.79%
6 months	+42.28%	+29.15%
1 year	+210.53%	+21.03%
5 years(CAGR)	+12.91%	+10.74%
10 years(CAGR)	N/A	-1.50%
Max(CAGR)	+12.91%	+2.69%

CNTA

+0.81%

Winner

ALKS

+10.23%

Winner

CNTA

+62.49%

ALKS

+15.79%

Winner

CNTA

+42.28%

ALKS

+29.15%

Winner

CNTA

+210.53%

ALKS

+21.03%

5Y(CAGR)

Winner

CNTA

+12.91%

ALKS

+10.74%

10Y(CAGR)

CNTA

N/A

ALKS

-1.50%

Max(CAGR)

Winner

CNTA

+12.91%

ALKS

+2.69%

CNTA vs ALKS - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	CNTA	ALKS
2026	+68.05%	+30.75%
2025	+42.91%	-2.68%
2024	+108.59%	+0.49%
2023	+154.31%	+7.23%
2022	-73.25%	+8.20%
2021	-48.23%	+17.83%
2020	N/A	+0.96%
2019	N/A	-29.92%
2018	N/A	-46.56%
2017	N/A	-2.44%
2016	N/A	-25.72%
2015	N/A	+36.30%
2014	N/A	+45.53%
2013	N/A	+110.89%
2012	N/A	+6.81%
2011	N/A	+38.33%
2010	N/A	+26.47%
2009	N/A	-12.14%
2008	N/A	-29.47%
2007	N/A	+19.10%
2006	N/A	-34.84%
2005	N/A	+36.47%
2004	N/A	+0.86%
2003	N/A	+102.70%
2002	N/A	-75.65%
2001	N/A	-4.60%
2000	N/A	+27.74%
1999	N/A	+34.60%

CNTA vs ALKS Drawdown Comparison

The maximum drawdown for CNTA was -88.19%, occurring on Feb 16, 2023. Recovery took 1107 trading sessions.

The maximum drawdown for ALKS was -96.14%, occurring on Jul 11, 2002. This drawdown has not yet recovered.

The current CNTA drawdown is -0.13%. The current ALKS drawdown is -62.32%.

Rank	CNTA	ALKS
#1	-88.19% Jun 17, 2021 - Nov 12, 2025	-96.14% Mar 1, 2000 - Jul 11, 2002
#2	-26.38% Dec 5, 2025 - Mar 31, 2026	-14.44% Jan 20, 2000 - Feb 3, 2000
#3	-13.54% Jun 2, 2021 - Jun 17, 2021	-12.68% Nov 26, 1999 - Dec 17, 1999
#4	-3.06% Nov 24, 2025 - Dec 4, 2025	-10.50% Dec 23, 1999 - Jan 7, 2000
#5	-2.89% Nov 18, 2025 - Nov 24, 2025	-9.45% Feb 18, 2000 - Feb 29, 2000
#6	-2.73% Nov 12, 2025 - Nov 14, 2025	-4.37% Nov 11, 1999 - Nov 16, 1999
#7	-1.10% Apr 1, 2026 - Apr 30, 2026	-4.12% Feb 11, 2000 - Feb 16, 2000
#8	-1.05% Nov 14, 2025 - Nov 18, 2025	-3.50% Jan 10, 2000 - Jan 13, 2000
#9	N/A	-3.33% Feb 8, 2000 - Feb 10, 2000
#10	N/A	-2.86% Nov 16, 1999 - Nov 22, 1999
#11	N/A	-2.52% Nov 2, 1999 - Nov 5, 1999
#12	N/A	-2.49% Nov 22, 1999 - Nov 26, 1999
#13	N/A	-0.62% Nov 9, 1999 - Nov 11, 1999
#14	N/A	-0.49% Dec 21, 1999 - Dec 23, 1999