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CDXS vs SPY

Comparison between Codexis Inc (CDXS, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed CDXS, delivering a return of +13.3% compared to -43.4%

CDXS vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
CDXS
$132M
Winner
SPY
$781B
Expense Ratio
CDXS
N/A
SPY
0.09%
Max Drawdown
CDXS
97.65%
Winner
SPY
56.47%
Sharpe Ratio
CDXS
-0.43
Winner
SPY
1.42
5Y Beta
CDXS
1.82
Winner
SPY
1.00
Industry
CDXS
Biotechnology
SPY
N/A
P/E Ratio
Winner
CDXS
-4.10
SPY
26.48
Forward P/E
CDXS
149.25
Winner
SPY
20.90
PEG Ratio
CDXS
13.53
Winner
SPY
0.30
5Y Dividends CAGR
CDXS
N/A
SPY
6.00%
5Y EPS CAGR
CDXS
-2.98%
Winner
SPY
26.40%
Debt to Equity
CDXS
93.64%
Winner
SPY
48.17%
Free Cash Flow Yield
CDXS
-16.78%
SPY
N/A
P/S Ratio
Winner
CDXS
2.00
SPY
3.72
P/B Ratio
Winner
CDXS
3.48
SPY
5.55

CDXS vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
CDXS
-43.46%
Winner
SPY
+3.42%
3M
CDXS
-43.02%
Winner
SPY
+5.97%
6M
CDXS
+10.53%
Winner
SPY
+12.56%
1Y
CDXS
-47.12%
Winner
SPY
+23.65%
5Y(CAGR)
CDXS
-43.39%
Winner
SPY
+13.33%
10Y(CAGR)
CDXS
-10.14%
Winner
SPY
+15.34%
Max(CAGR)
CDXS
-12.63%
Winner
SPY
+8.61%

CDXS vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearCDXSSPY
2026-8.70%+13.79%
2025-67.40%+18.00%
2024+52.88%+25.59%
2023-34.69%+26.72%
2022-85.41%-18.64%
2021+45.92%+30.52%
2020+32.95%+17.28%
2019-0.74%+31.09%
2018+104.91%-5.24%
2017+85.56%+20.78%
2016+9.00%+13.59%
2015+51.61%+1.31%
2014+76.22%+14.56%
2013-45.10%+29.00%
2012-59.67%+14.17%
2011-49.62%+0.85%
2010-20.06%+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

CDXS vs SPY Drawdown Comparison

The maximum drawdown for CDXS was -97.65%, occurring on Mar 3, 2026. This drawdown has not yet recovered.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current CDXS drawdown is -96.48%.

RankCDXSSPY
#1-97.65%
Nov 8, 2021 - Mar 3, 2026		-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-91.35%
Apr 26, 2010 - May 30, 2018		-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-61.10%
Dec 3, 2018 - Dec 22, 2020		-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-39.31%
Feb 8, 2021 - Oct 7, 2021		-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-26.39%
Sep 25, 2018 - Nov 28, 2018		-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-18.84%
Jun 20, 2018 - Aug 27, 2018		-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-16.02%
Jan 19, 2021 - Feb 2, 2021		-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-14.76%
Oct 8, 2021 - Oct 26, 2021		-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-9.91%
Dec 22, 2020 - Jan 8, 2021		-9.44%
Sep 2, 2020 - Nov 11, 2020
#10-7.42%
Jun 7, 2018 - Jun 19, 2018		-9.30%
Jan 19, 2000 - Mar 17, 2000
#11-4.92%
Jan 8, 2021 - Jan 14, 2021		-9.05%
Jul 19, 2007 - Oct 5, 2007
#12-4.77%
Sep 13, 2018 - Sep 25, 2018		-8.88%
Jan 27, 2026 - Apr 14, 2026
#13-3.59%
Oct 28, 2021 - Nov 4, 2021		-8.41%
Jul 16, 2024 - Sep 19, 2024
#14-3.04%
Aug 27, 2018 - Sep 5, 2018		-7.35%
Sep 14, 2012 - Jan 2, 2013
#15-2.33%
Jun 1, 2018 - Jun 7, 2018		-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between CDXS and SPY is 0.00 which considered as a very weak or no correlation - the stocks move independently of each other.

0.00
-101

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