CDXS vs ADAG

Comparison between Codexis Inc (CDXS, Company) and Adagene Inc (ADAG, Company).

Both CDXS and ADAG are from the Healthcare sector.

5-Year PerformanceADAG has outperformed CDXS, delivering a return of -22.4% compared to -35.0%

CDXS vs ADAG - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CDXS(COMPANY)	ADAG(COMPANY)
Market Cap	$234M	$233M
Max Drawdown	97.65%	97.00%
Sharpe Ratio	0.53	1.17
5Y Beta	1.83	0.38
Industry	Biotechnology	Biotechnology
P/E Ratio	-7.26	-13.25
Forward P/E	149.25	N/A
5Y EPS CAGR	-2.98%	-34.96%
Debt to Equity	93.64%	5.23%
Free Cash Flow Yield	-9.47%	-6.71%

Market Cap

Winner

CDXS

$234M

ADAG

$233M

Max Drawdown

CDXS

97.65%

Winner

ADAG

97.00%

Sharpe Ratio

CDXS

0.53

Winner

ADAG

1.17

5Y Beta

CDXS

1.83

Winner

ADAG

0.38

Industry

CDXS

Biotechnology

ADAG

Biotechnology

P/E Ratio

CDXS

-7.26

Winner

ADAG

-13.25

Forward P/E

CDXS

149.25

ADAG

N/A

5Y EPS CAGR

Winner

CDXS

-2.98%

ADAG

-34.96%

Debt to Equity

CDXS

93.64%

Winner

ADAG

5.23%

Free Cash Flow Yield

CDXS

-9.47%

Winner

ADAG

-6.71%

CDXS vs ADAG - Historical Returns

Returns include dividend reinvestment.

Period	CDXS	ADAG
1 month	+0.78%	+16.22%
3 months	+74.83%	+0.00%
6 months	+56.71%	+115.30%
1 year	+9.36%	+102.05%
5 years(CAGR)	-34.99%	-22.40%
10 years(CAGR)	-4.75%	N/A
Max(CAGR)	-9.66%	-31.56%

CDXS

+0.78%

Winner

ADAG

+16.22%

Winner

CDXS

+74.83%

ADAG

+0.00%

CDXS

+56.71%

Winner

ADAG

+115.30%

CDXS

+9.36%

Winner

ADAG

+102.05%

5Y(CAGR)

CDXS

-34.99%

Winner

ADAG

-22.40%

10Y(CAGR)

CDXS

-4.75%

ADAG

N/A

Max(CAGR)

Winner

CDXS

-9.66%

ADAG

-31.56%

CDXS vs ADAG - Annual Returns (2010 - 2026)

Returns include dividend reinvestment.

Year	CDXS	ADAG
2026	+59.63%	+114.13%
2025	-67.40%	-8.25%
2024	+52.88%	+1.53%
2023	-34.69%	+52.08%
2022	-85.41%	-83.52%
2021	+45.92%	-73.10%
2020	+32.95%	N/A
2019	-0.74%	N/A
2018	+104.91%	N/A
2017	+85.56%	N/A
2016	+9.00%	N/A
2015	+51.61%	N/A
2014	+76.22%	N/A
2013	-45.10%	N/A
2012	-59.67%	N/A
2011	-49.62%	N/A
2010	-20.06%	N/A

CDXS vs ADAG Drawdown Comparison

The maximum drawdown for CDXS was -97.65%, occurring on Mar 3, 2026. This drawdown has not yet recovered.

The maximum drawdown for ADAG was -97.00%, occurring on Oct 31, 2022. This drawdown has not yet recovered.

The current CDXS drawdown is -93.85%. The current ADAG drawdown is -86.86%.

Rank	CDXS	ADAG
#1	-97.65% Nov 8, 2021 - Mar 3, 2026	-97.00% Feb 9, 2021 - Oct 31, 2022
#2	-91.35% Apr 26, 2010 - May 30, 2018	N/A
#3	-61.10% Dec 3, 2018 - Dec 22, 2020	N/A
#4	-39.31% Feb 8, 2021 - Oct 7, 2021	N/A
#5	-26.39% Sep 25, 2018 - Nov 28, 2018	N/A
#6	-18.84% Jun 20, 2018 - Aug 27, 2018	N/A
#7	-16.02% Jan 19, 2021 - Feb 2, 2021	N/A
#8	-14.76% Oct 8, 2021 - Oct 26, 2021	N/A
#9	-9.91% Dec 22, 2020 - Jan 8, 2021	N/A
#10	-7.42% Jun 7, 2018 - Jun 19, 2018	N/A
#11	-4.92% Jan 8, 2021 - Jan 14, 2021	N/A
#12	-4.77% Sep 13, 2018 - Sep 25, 2018	N/A
#13	-3.59% Oct 28, 2021 - Nov 4, 2021	N/A
#14	-3.04% Aug 27, 2018 - Sep 5, 2018	N/A
#15	-2.33% Jun 1, 2018 - Jun 7, 2018	N/A