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CASI vs SPY

Comparison between CASI Pharmaceuticals Inc (CASI, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed CASI, delivering a return of +14.0% compared to -57.7%

CASI vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
CASI
$4.27M
Winner
SPY
$784B
Expense Ratio
CASI
N/A
SPY
0.09%
Max Drawdown
CASI
100.00%
Winner
SPY
56.47%
Sharpe Ratio
CASI
-0.94
Winner
SPY
1.68
5Y Beta
CASI
N/A
SPY
1.00
Industry
CASI
Biotechnology
SPY
N/A
P/E Ratio
Winner
CASI
-0.09
SPY
28.06
Forward P/E
CASI
N/A
SPY
21.47
PEG Ratio
CASI
N/A
SPY
0.36
5Y Dividends CAGR
CASI
N/A
SPY
6.00%
5Y EPS CAGR
CASI
-11.77%
Winner
SPY
25.05%
Debt to Equity
Winner
CASI
-51.47%
SPY
30.60%

CASI vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
CASI
+0.00%
Winner
SPY
+1.35%
3M
CASI
+0.00%
Winner
SPY
+13.50%
6M
CASI
-75.05%
Winner
SPY
+11.30%
1Y
CASI
-84.74%
Winner
SPY
+26.75%
5Y(CAGR)
CASI
-57.69%
Winner
SPY
+14.01%
10Y(CAGR)
CASI
-33.40%
Winner
SPY
+15.56%
Max(CAGR)
CASI
-29.69%
Winner
SPY
+8.52%

CASI vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearCASISPY
2026-74.82%+9.89%
2025-71.48%+18.00%
2024-60.80%+25.59%
2023+289.13%+26.72%
2022-78.84%-18.64%
2021-71.93%+30.52%
2020-5.75%+17.28%
2019-21.77%+31.09%
2018+12.29%-5.24%
2017+162.10%+20.78%
2016+19.79%+13.59%
2015-31.91%+1.31%
2014-30.58%+14.56%
2013+21.09%+29.00%
2012+20.00%+14.17%
2011-82.18%+0.85%
2010-44.37%+13.14%
2009+396.89%+22.67%
2008-86.50%-36.25%
2007-25.00%+5.32%
2006-20.60%+13.85%
2005-39.56%+5.32%
2004-10.50%+10.75%
2003+176.67%+24.18%
2002-89.60%-22.42%
2001-51.88%-10.13%
2000-39.47%-8.84%
1999+14.52%+8.61%

CASI vs SPY Drawdown Comparison

The maximum drawdown for CASI was -100.00%, occurring on Feb 25, 2026. This drawdown has not yet recovered.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current CASI drawdown is -100.00%. The current SPY drawdown is -1.44%.

RankCASISPY
#1-100.00%
Feb 29, 2000 - Feb 25, 2026
-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-31.07%
Jan 20, 2000 - Feb 16, 2000
-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-19.12%
Dec 9, 1999 - Jan 10, 2000
-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-7.94%
Nov 18, 1999 - Dec 9, 1999
-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-5.90%
Nov 3, 1999 - Nov 18, 1999
-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-2.85%
Feb 22, 2000 - Feb 24, 2000
-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-2.43%
Jan 11, 2000 - Jan 14, 2000
-13.02%
Jul 20, 2015 - Apr 18, 2016
#8N/A-10.10%
Jan 26, 2018 - Aug 6, 2018
#9N/A-9.44%
Sep 2, 2020 - Nov 11, 2020
#10N/A-9.30%
Jan 19, 2000 - Mar 17, 2000
#11N/A-9.05%
Jul 19, 2007 - Oct 5, 2007
#12N/A-8.88%
Jan 27, 2026 - Apr 14, 2026
#13N/A-8.41%
Jul 16, 2024 - Sep 19, 2024
#14N/A-7.35%
Sep 14, 2012 - Jan 2, 2013
#15N/A-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between CASI and SPY is -0.23 which considered as a very weak or no correlation - the stocks move independently of each other.

-0.23
-101

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