CANC vs IPAY

Comparison between Tema Oncology ETF (CANC, ETF) and Amplify Mobile Payments ETF (IPAY, ETF).

5-Year PerformanceIPAY has outperformed CANC, delivering a return of -8.8% compared to -10.0%

CANC vs IPAY - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CANC(ETF)	IPAY(ETF)
Net Assets	$176M	$174M
Expense Ratio	0.75%	0.75%
Max Drawdown	97.53%	51.75%
Sharpe Ratio	1.56	-1.18
5Y Beta	0.76	1.17
P/E Ratio	-29.15	19.97
Forward P/E	N/A	12.21
PEG Ratio	N/A	0.36
5Y EPS CAGR	11.87%	N/A
Debt to Equity	58.15%	122.34%
P/S Ratio	8.53	1.57
P/B Ratio	6.45	2.40

Net Assets

Winner

CANC

$176M

IPAY

$174M

Expense Ratio

CANC

0.75%

IPAY

0.75%

Max Drawdown

CANC

97.53%

Winner

IPAY

51.75%

Sharpe Ratio

Winner

CANC

1.56

IPAY

-1.18

5Y Beta

Winner

CANC

0.76

IPAY

1.17

P/E Ratio

Winner

CANC

-29.15

IPAY

19.97

Forward P/E

CANC

N/A

IPAY

12.21

PEG Ratio

CANC

N/A

IPAY

0.36

5Y EPS CAGR

CANC

11.87%

IPAY

N/A

Debt to Equity

Winner

CANC

58.15%

IPAY

122.34%

P/S Ratio

CANC

8.53

Winner

IPAY

1.57

P/B Ratio

CANC

6.45

Winner

IPAY

2.40

CANC vs IPAY - Holdings Comparison

CANC and IPAY have 1 common holdings. Overlap is -0.02%

CANC's top 25 holdings weight is 76.89%. IPAY's top 25 holdings weight is 91.58%.

Rank	CANC	IPAY
#1	REVOLUTION MEDICINES INC ORDINARY SHARES (RVMD) - 7.31%	AFFIRM HOLDINGS INC ORDINARY SHARES CLASS A (AFRM) - 6.14%
#2	ELI LILLY AND CO (LLY) - 4.25%	VISA INC CLASS A (V) - 6.14%
#3	IMMUNOME INC ORDINARY SHARES (IMNM) - 4.21%	BLOCK INC CLASS A (XYZ) - 5.89%
#4	COGENT BIOSCIENCES INC (COGT) - 4.08%	ADYEN NV (n/a) - 5.77%
#5	ROCHE HOLDING AG ADR (RHHBY) - 4.07%	MASTERCARD INC CLASS A (MA) - 5.66%
#6	NOVARTIS AG REGISTERED SHARES (n/a) - 4.00%	AMERICAN EXPRESS CO (AXP) - 5.42%
#7	CELCUITY INC (CELC) - 3.93%	CAPITAL ONE FINANCIAL CORP (COF) - 5.40%
#8	ASTRAZENECA PLC (AZN:XLON) - 3.50%	WISE GROUP PLC CLASS A (WSE) - 4.94%
#9	MERCK & CO INC (MRK) - 3.43%	PAYPAL HOLDINGS INC (PYPL) - 4.80%
#10	BRISTOL-MYERS SQUIBB CO (BMY) - 3.34%	COINBASE GLOBAL INC ORDINARY SHARES CLASS A (COIN) - 4.76%
#11	NUVALENT INC CLASS A (NUVL) - 3.15%	CORPAY INC (CPAY) - 4.49%
#12	LEGEND BIOTECH CORP ADR (LEGN) - 2.94%	FISERV INC (FISV) - 4.10%
#13	GENMAB AS ADR (GMAB) - 2.87%	GLOBAL PAYMENTS INC (GPN) - 4.02%
#14	ABBVIE INC (ABBV) - 2.70%	TOAST INC CLASS A (TOST) - 3.90%
#15	BRIDGEBIO PHARMA INC (BBIO) - 2.63%	FIDELITY NATIONAL INFORMATION SERVICES INC (FIS) - 3.89%
#16	CG ONCOLOGY INC (CGON) - 2.56%	WEX INC (WEX) - 2.41%
#17	JOHNSON & JOHNSON (JNJ) - 2.55%	ACI WORLDWIDE INC (ACIW) - 1.94%
#18	ZAI LAB LTD ADR REPR 1 SHS (ZLAB) - 2.49%	REMITLY GLOBAL INC (RELY) - 1.82%
#19	EXELIXIS INC (EXEL) - 2.45%	NEXI SPA (n/a) - 1.74%
#20	IDEAYA BIOSCIENCES INC (IDYA) - 2.10%	STONECO LTD CLASS A (STNE) - 1.74%
#21	AMGEN INC (AMGN) - 2.04%	GMO PAYMENT GATEWAY INC (n/a) - 1.50%
#22	BEONE MEDICINES LTD ADR (ONC) - 1.95%	EURONET WORLDWIDE INC (EEFT) - 1.47%
#23	ZYMEWORKS INC REGISTERED SHS (ZYME) - 1.62%	THE WESTERN UNION CO (WU) - 1.26%
#24	FIRST AMERICAN TREASURY OBLIGS X (FXFXX) - 1.47%	Q2 HOLDINGS INC (QTWO) - 1.19%
#25	ANAPTYSBIO INC (ANAB) - 1.25%	ZIP CO LTD (n/a) - 1.19%
Total Holdings	57	43

CANC vs IPAY - Historical Returns

Returns include dividend reinvestment.

Period	CANC	IPAY
1 month	-3.84%	-8.03%
3 months	-0.74%	-6.38%
6 months	+3.88%	-16.43%
1 year	+46.70%	-24.27%
5 years(CAGR)	-9.97%	-8.83%
10 years(CAGR)	N/A	+5.82%
Max(CAGR)	-9.97%	+5.18%

Winner

CANC

-3.84%

IPAY

-8.03%

Winner

CANC

-0.74%

IPAY

-6.38%

Winner

CANC

+3.88%

IPAY

-16.43%

Winner

CANC

+46.70%

IPAY

-24.27%

5Y(CAGR)

CANC

-9.97%

Winner

IPAY

-8.83%

10Y(CAGR)

CANC

N/A

IPAY

+5.82%

Max(CAGR)

CANC

-9.97%

Winner

IPAY

+5.18%

CANC vs IPAY - Annual Returns (2015 - 2026)

Returns include dividend reinvestment.

Year	CANC	IPAY
2026	+5.32%	-16.30%
2025	+42.13%	-9.72%
2024	-6.11%	+27.55%
2023	+515.06%	+18.33%
2022	-85.58%	-33.83%
2021	-51.82%	-11.52%
2020	N/A	+32.25%
2019	N/A	+41.36%
2018	N/A	-0.03%
2017	N/A	+34.66%
2016	N/A	+6.72%
2015	N/A	-2.75%

CANC vs IPAY Drawdown Comparison

The maximum drawdown for CANC was -97.53%, occurring on Apr 5, 2023. This drawdown has not yet recovered.

The maximum drawdown for IPAY was -51.75%, occurring on Oct 27, 2023. This drawdown has not yet recovered.

The current CANC drawdown is -56.51%. The current IPAY drawdown is -39.93%.

Rank	CANC	IPAY
#1	-97.53% Oct 20, 2021 - Apr 5, 2023	-51.75% Apr 28, 2021 - Oct 27, 2023
#2	-16.18% Oct 5, 2021 - Oct 20, 2021	-42.94% Feb 19, 2020 - Aug 24, 2020
#3	N/A	-25.01% Sep 25, 2018 - Apr 1, 2019
#4	N/A	-21.72% Oct 28, 2015 - Jan 3, 2017
#5	N/A	-12.48% Oct 12, 2020 - Nov 9, 2020
#6	N/A	-10.15% Jan 26, 2018 - May 17, 2018
#7	N/A	-10.04% Jul 29, 2019 - Jan 2, 2020
#8	N/A	-9.86% Aug 18, 2015 - Oct 28, 2015
#9	N/A	-8.76% Sep 2, 2020 - Oct 12, 2020
#10	N/A	-8.12% Feb 16, 2021 - Apr 15, 2021
#11	N/A	-6.73% Jan 8, 2021 - Feb 4, 2021
#12	N/A	-5.35% Apr 30, 2019 - May 22, 2019
#13	N/A	-4.77% Jul 25, 2018 - Aug 24, 2018
#14	N/A	-4.46% Jun 18, 2018 - Jul 12, 2018
#15	N/A	-3.83% May 22, 2019 - Jun 5, 2019