CABA vs PRTA

Comparison between Cabaletta Bio Inc (CABA, Company) and Prothena Corporation plc (PRTA, Company).

Both CABA and PRTA are from the Healthcare sector.

5-Year PerformanceCABA has outperformed PRTA, delivering a return of -17.6% compared to -29.4%

CABA vs PRTA - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CABA(COMPANY)	PRTA(COMPANY)
Market Cap	$475M	$474M
Max Drawdown	96.63%	94.19%
Sharpe Ratio	0.85	1.09
5Y Beta	1.68	0.94
Industry	Biotechnology	Biotechnology
P/E Ratio	-2.06	-3.19
Forward P/E	N/A	10.63
PEG Ratio	N/A	-0.09
5Y EPS CAGR	8.20%	-1.54%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-30.17%	-17.16%

Market Cap

Winner

CABA

$475M

PRTA

$474M

Max Drawdown

CABA

96.63%

Winner

PRTA

94.19%

Sharpe Ratio

CABA

0.85

Winner

PRTA

1.09

5Y Beta

CABA

1.68

Winner

PRTA

0.94

Industry

CABA

Biotechnology

PRTA

Biotechnology

P/E Ratio

CABA

-2.06

Winner

PRTA

-3.19

Forward P/E

CABA

N/A

PRTA

10.63

PEG Ratio

CABA

N/A

PRTA

-0.09

5Y EPS CAGR

Winner

CABA

8.20%

PRTA

-1.54%

Debt to Equity

CABA

0.00%

PRTA

0.00%

Free Cash Flow Yield

CABA

-30.17%

Winner

PRTA

-17.16%

CABA vs PRTA - Historical Returns

Returns include dividend reinvestment.

Period	CABA	PRTA
1 month	-13.68%	-6.88%
3 months	-4.38%	+3.96%
6 months	+17.84%	-4.80%
1 year	+64.16%	+55.30%
5 years(CAGR)	-17.59%	-29.43%
10 years(CAGR)	N/A	-13.89%
Max(CAGR)	-17.25%	+1.61%

CABA

-13.68%

Winner

PRTA

-6.88%

CABA

-4.38%

Winner

PRTA

+3.96%

Winner

CABA

+17.84%

PRTA

-4.80%

Winner

CABA

+64.16%

PRTA

+55.30%

5Y(CAGR)

Winner

CABA

-17.59%

PRTA

-29.43%

10Y(CAGR)

CABA

N/A

PRTA

-13.89%

Max(CAGR)

CABA

-17.25%

Winner

PRTA

+1.61%

CABA vs PRTA - Annual Returns (2012 - 2026)

Returns include dividend reinvestment.

Year	CABA	PRTA
2026	+28.51%	-2.93%
2025	-6.01%	-30.14%
2024	-89.76%	-64.06%
2023	+141.49%	-32.07%
2022	+137.18%	+22.41%
2021	-70.57%	+301.63%
2020	-10.22%	-23.16%
2019	+39.70%	+50.76%
2018	N/A	-72.75%
2017	N/A	-24.70%
2016	N/A	-20.94%
2015	N/A	+234.69%
2014	N/A	-26.12%
2013	N/A	+278.86%
2012	N/A	+1.81%

CABA vs PRTA Drawdown Comparison

The maximum drawdown for CABA was -96.63%, occurring on Sep 23, 2022. Recovery took 964 trading sessions.

The maximum drawdown for PRTA was -94.19%, occurring on May 27, 2025. This drawdown has not yet recovered.

The current CABA drawdown is -88.81%. The current PRTA drawdown is -88.68%.

Rank	CABA	PRTA
#1	-96.63% Jan 29, 2020 - Nov 27, 2023	-94.19% Sep 23, 2021 - May 27, 2025
#2	-95.90% Feb 8, 2024 - Apr 8, 2025	-90.85% Nov 27, 2015 - Sep 10, 2021
#3	-55.51% Nov 19, 2019 - Jan 29, 2020	-64.27% Mar 20, 2014 - Jun 17, 2015
#4	-26.79% Nov 27, 2023 - Dec 13, 2023	-36.96% Jul 28, 2015 - Nov 18, 2015
#5	-19.64% Jan 8, 2024 - Feb 8, 2024	-20.33% Dec 31, 2012 - Apr 9, 2013
#6	-15.45% Nov 11, 2019 - Nov 15, 2019	-18.45% Jun 20, 2013 - Jul 12, 2013
#7	-6.59% Dec 27, 2023 - Jan 8, 2024	-17.61% Jan 30, 2014 - Feb 25, 2014
#8	-4.83% Dec 19, 2023 - Dec 26, 2023	-15.12% Dec 16, 2013 - Jan 29, 2014
#9	-1.50% Nov 15, 2019 - Nov 19, 2019	-14.72% Oct 2, 2013 - Oct 25, 2013
#10	-1.41% Oct 30, 2019 - Nov 1, 2019	-11.68% May 28, 2013 - Jun 7, 2013
#11	N/A	-10.76% Aug 2, 2013 - Aug 22, 2013
#12	N/A	-10.14% Jun 22, 2015 - Jul 14, 2015
#13	N/A	-7.65% Mar 12, 2014 - Mar 19, 2014
#14	N/A	-6.94% Aug 29, 2013 - Oct 2, 2013
#15	N/A	-6.73% Jul 22, 2015 - Jul 28, 2015