BMRN vs MDGL

Comparison between Biomarin Pharmaceutical Inc (BMRN, Company) and Madrigal Pharmaceuticals Inc (MDGL, Company).

Both BMRN and MDGL are from the Healthcare sector.

5-Year PerformanceMDGL has outperformed BMRN, delivering a return of +34.5% compared to -7.5%

BMRN vs MDGL - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	BMRN(COMPANY)	MDGL(COMPANY)
Market Cap	$11B	$11B
Max Drawdown	90.58%	98.40%
Sharpe Ratio	-0.04	1.27
5Y Beta	0.68	0.73
Industry	Biotechnology	Biotechnology
P/E Ratio	40.22	-34.67
Forward P/E	11.63	666.67
PEG Ratio	0.71	0.00
5Y EPS CAGR	-20.33%	23.26%
Debt to Equity	23.02%	62.62%
Free Cash Flow Yield	7.07%	-2.52%
P/S Ratio	3.45	9.68
P/B Ratio	1.80	20.25

Market Cap

BMRN

$11B

Winner

MDGL

$11B

Max Drawdown

Winner

BMRN

90.58%

MDGL

98.40%

Sharpe Ratio

BMRN

-0.04

Winner

MDGL

1.27

5Y Beta

Winner

BMRN

0.68

MDGL

0.73

Industry

BMRN

Biotechnology

MDGL

Biotechnology

P/E Ratio

BMRN

40.22

Winner

MDGL

-34.67

Forward P/E

Winner

BMRN

11.63

MDGL

666.67

PEG Ratio

BMRN

0.71

Winner

MDGL

0.00

5Y EPS CAGR

BMRN

-20.33%

Winner

MDGL

23.26%

Debt to Equity

Winner

BMRN

23.02%

MDGL

62.62%

Free Cash Flow Yield

Winner

BMRN

7.07%

MDGL

-2.52%

P/S Ratio

Winner

BMRN

3.45

MDGL

9.68

P/B Ratio

Winner

BMRN

1.80

MDGL

20.25

BMRN vs MDGL - Historical Returns

Returns include dividend reinvestment.

Period	BMRN	MDGL
1 month	+5.63%	-4.58%
3 months	-7.92%	+9.91%
6 months	+4.81%	-16.99%
1 year	-2.83%	+61.13%
5 years(CAGR)	-7.51%	+34.46%
10 years(CAGR)	-3.71%	+44.09%
Max(CAGR)	+4.94%	+2.09%

Winner

BMRN

+5.63%

MDGL

-4.58%

BMRN

-7.92%

Winner

MDGL

+9.91%

Winner

BMRN

+4.81%

MDGL

-16.99%

BMRN

-2.83%

Winner

MDGL

+61.13%

5Y(CAGR)

BMRN

-7.51%

Winner

MDGL

+34.46%

10Y(CAGR)

BMRN

-3.71%

Winner

MDGL

+44.09%

Max(CAGR)

Winner

BMRN

+4.94%

MDGL

+2.09%

BMRN vs MDGL - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	BMRN	MDGL
2026	-6.58%	-20.14%
2025	-10.62%	+85.59%
2024	-32.96%	+36.02%
2023	-4.16%	-18.93%
2022	+15.81%	+222.07%
2021	+2.38%	-22.80%
2020	+4.34%	+22.60%
2019	-0.48%	-18.06%
2018	-6.46%	+15.71%
2017	+3.88%	+475.13%
2016	-21.04%	+28.97%
2015	+13.66%	-87.74%
2014	+30.50%	-49.62%
2013	+35.50%	-45.64%
2012	+40.85%	+84.46%
2011	+29.20%	-24.56%
2010	+42.11%	+10.87%
2009	+6.57%	-17.99%
2008	-51.42%	-3.62%
2007	+119.88%	-26.29%
2006	+49.14%	N/A
2005	+72.20%	N/A
2004	-19.22%	N/A
2003	+10.38%	N/A
2002	-46.75%	N/A
2001	+41.47%	N/A
2000	-24.02%	N/A
1999	-23.60%	N/A

BMRN vs MDGL Drawdown Comparison

The maximum drawdown for BMRN was -90.58%, occurring on Aug 27, 2002. Recovery took 1974 trading sessions.

The maximum drawdown for MDGL was -98.40%, occurring on Feb 11, 2016. Recovery took 3162 trading sessions.

The current BMRN drawdown is -62.76%. The current MDGL drawdown is -21.32%.

Rank	BMRN	MDGL
#1	-90.58% Mar 1, 2000 - Jan 8, 2008	-98.40% Jan 28, 2013 - Aug 22, 2025
#2	-74.89% Feb 14, 2008 - Jul 2, 2012	-87.64% Oct 5, 2007 - Jan 22, 2013
#3	-66.69% Jul 20, 2015 - May 18, 2026	-51.43% Jun 4, 2007 - Oct 4, 2007
#4	-33.02% Feb 27, 2014 - Nov 3, 2014	-29.36% Dec 22, 2025 - Mar 3, 2026
#5	-24.97% Nov 2, 1999 - Jan 14, 2000	-18.88% Feb 9, 2007 - Jun 4, 2007
#6	-24.35% Sep 19, 2013 - Feb 20, 2014	-10.10% Sep 30, 2025 - Nov 5, 2025
#7	-22.16% May 14, 2013 - Sep 5, 2013	-9.42% Nov 26, 2025 - Dec 22, 2025
#8	-15.06% Jul 13, 2012 - Nov 5, 2012	-8.01% Sep 8, 2025 - Sep 30, 2025
#9	-14.15% Jan 14, 2000 - Feb 8, 2000	-4.91% Nov 11, 2025 - Nov 17, 2025
#10	-13.23% Mar 30, 2015 - May 27, 2015	-4.32% Jan 23, 2013 - Jan 25, 2013
#11	-12.73% Jan 9, 2008 - Feb 14, 2008	-3.02% Nov 18, 2025 - Nov 24, 2025
#12	-9.37% Mar 19, 2015 - Mar 27, 2015	-1.52% Aug 29, 2025 - Sep 8, 2025
#13	-8.63% Dec 9, 2014 - Jan 12, 2015	-0.59% Aug 22, 2025 - Aug 26, 2025
#14	-7.01% May 27, 2015 - Jun 18, 2015	N/A
#15	-6.98% Sep 9, 2013 - Sep 18, 2013	N/A

Correlation

Correlation between BMRN and MDGL is -0.32 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.32

-101