AXSM vs SF

Comparison between Axsome Therapeutics Inc (AXSM, Company) and Stifel Financial Corp (SF, Company).

AXSM is from the Healthcare sector, while SF is from the Financial Services sector.

5-Year PerformanceAXSM has outperformed SF, delivering a return of +33.5% compared to +14.8%

AXSM vs SF - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AXSM(COMPANY)	SF(COMPANY)
Market Cap	$12B	$12B
Max Drawdown	86.65%	55.25%
Sharpe Ratio	1.83	0.35
5Y Beta	0.66	1.30
Industry	Biotechnology	Capital Markets
P/E Ratio	-63.88	18.23
Forward P/E	333.33	12.06
PEG Ratio	0.00	0.84
Dividend Yield	N/A	1.60%
5Y Dividends CAGR	N/A	35.74%
5Y EPS CAGR	6.89%	11.92%
Debt to Equity	344.13%	10.32%
Free Cash Flow Yield	-0.58%	8.05%
P/S Ratio	17.09	2.07
P/B Ratio	221.78	2.18

Market Cap

AXSM

$12B

Winner

$12B

Max Drawdown

AXSM

86.65%

Winner

55.25%

Sharpe Ratio

Winner

AXSM

1.83

0.35

5Y Beta

Winner

AXSM

0.66

1.30

Industry

AXSM

Biotechnology

Capital Markets

P/E Ratio

Winner

AXSM

-63.88

18.23

Forward P/E

AXSM

333.33

Winner

12.06

PEG Ratio

Winner

AXSM

0.00

0.84

Dividend Yield

AXSM

N/A

1.60%

5Y Dividends CAGR

AXSM

N/A

35.74%

5Y EPS CAGR

AXSM

6.89%

Winner

11.92%

Debt to Equity

AXSM

344.13%

Winner

10.32%

Free Cash Flow Yield

AXSM

-0.58%

Winner

8.05%

P/S Ratio

AXSM

17.09

Winner

2.07

P/B Ratio

AXSM

221.78

Winner

2.18

AXSM vs SF - Historical Returns

Returns include dividend reinvestment.

Period	AXSM	SF
1 month	-8.79%	+5.51%
3 months	+21.70%	-5.38%
6 months	+29.75%	-9.51%
1 year	+104.92%	+7.91%
5 years(CAGR)	+33.49%	+14.78%
10 years(CAGR)	+39.81%	+19.57%
Max(CAGR)	+35.91%	+16.40%

AXSM

-8.79%

Winner

+5.51%

Winner

AXSM

+21.70%

-5.38%

Winner

AXSM

+29.75%

-9.51%

Winner

AXSM

+104.92%

+7.91%

5Y(CAGR)

Winner

AXSM

+33.49%

+14.78%

10Y(CAGR)

Winner

AXSM

+39.81%

+19.57%

Max(CAGR)

Winner

AXSM

+35.91%

+16.40%

AXSM vs SF - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	AXSM	SF
2026	+28.71%	-8.53%
2025	+109.16%	+20.03%
2024	+9.80%	+56.07%
2023	+8.55%	+19.01%
2022	+103.89%	-17.01%
2021	-53.61%	+45.12%
2020	-19.58%	+24.74%
2019	+3756.72%	+48.01%
2018	-48.49%	-30.66%
2017	-13.18%	+19.75%
2016	-44.63%	+20.54%
2015	+6.06%	-16.30%
2014	N/A	+8.46%
2013	N/A	+44.21%
2012	N/A	-4.60%
2011	N/A	-23.70%
2010	N/A	+4.94%
2009	N/A	+29.63%
2008	N/A	+35.57%
2007	N/A	+34.90%
2006	N/A	+2.56%
2005	N/A	+85.90%
2004	N/A	+50.83%
2003	N/A	+77.28%
2002	N/A	+7.63%
2001	N/A	-4.65%
2000	N/A	+19.52%
1999	N/A	-6.80%

AXSM vs SF Drawdown Comparison

The maximum drawdown for AXSM was -86.65%, occurring on Dec 27, 2018. Recovery took 809 trading sessions.

The maximum drawdown for SF was -55.25%, occurring on Feb 24, 2016. Recovery took 618 trading sessions.

The current AXSM drawdown is -9.86%. The current SF drawdown is -11.91%.

Rank	AXSM	SF
#1	-86.65% Jan 5, 2016 - Mar 25, 2019	-55.25% Jun 23, 2015 - Dec 4, 2017
#2	-81.26% Dec 26, 2019 - Jan 30, 2025	-51.89% Feb 20, 2020 - Nov 9, 2020
#3	-42.70% Sep 16, 2019 - Nov 19, 2019	-50.85% Mar 8, 2011 - Jan 16, 2014
#4	-30.56% Feb 21, 2025 - Nov 6, 2025	-42.10% Feb 1, 2018 - Feb 4, 2020
#5	-18.50% Jan 21, 2026 - Apr 30, 2026	-41.41% Sep 19, 2008 - May 4, 2009
#6	-17.63% Mar 25, 2019 - Apr 25, 2019	-40.06% Oct 11, 2007 - Jul 23, 2008
#7	-17.48% Jul 26, 2019 - Sep 16, 2019	-36.25% Feb 8, 2022 - Mar 28, 2024
#8	-17.26% May 28, 2019 - Jun 20, 2019	-34.67% Jan 30, 2025 - Oct 22, 2025
#9	-11.38% Jun 20, 2019 - Jun 27, 2019	-32.45% Oct 16, 2000 - Nov 3, 2003
#10	-10.54% Jun 12, 2026 - Jul 13, 2026	-31.50% Mar 30, 2006 - Jan 11, 2007
#11	-10.33% Nov 24, 2015 - Dec 29, 2015	-27.20% Dec 30, 2009 - Dec 14, 2010
#12	-9.37% Jul 2, 2019 - Jul 26, 2019	-25.97% Mar 9, 2004 - Nov 22, 2004
#13	-8.83% Dec 4, 2019 - Dec 10, 2019	-22.74% Jan 6, 2026 - Jun 29, 2026
#14	-8.26% Dec 31, 2025 - Jan 20, 2026	-21.42% Feb 21, 2007 - May 25, 2007
#15	-7.23% Feb 5, 2025 - Feb 10, 2025	-19.86% Dec 3, 2004 - Jun 23, 2005