AXSM vs RNR

Comparison between Axsome Therapeutics Inc (AXSM, Company) and RenaissanceRe Holdings Ltd (RNR, Company).

AXSM is from the Healthcare sector, while RNR is from the Financial Services sector.

5-Year PerformanceAXSM has outperformed RNR, delivering a return of +30.0% compared to +16.8%

AXSM vs RNR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AXSM(COMPANY)	RNR(COMPANY)
Market Cap	$13B	$13B
Max Drawdown	86.65%	46.58%
Sharpe Ratio	2.28	0.87
5Y Beta	0.65	0.29
Industry	Biotechnology	Insurance - Reinsurance
P/E Ratio	-67.37	4.87
Forward P/E	333.33	9.07
PEG Ratio	N/A	0.05
Dividend Yield	N/A	0.54%
5Y Dividends CAGR	N/A	2.67%
5Y EPS CAGR	6.89%	41.69%
Debt to Equity	344.13%	20.24%
Free Cash Flow Yield	-0.55%	32.85%

Market Cap

Winner

AXSM

$13B

RNR

$13B

Max Drawdown

AXSM

86.65%

Winner

RNR

46.58%

Sharpe Ratio

Winner

AXSM

2.28

RNR

0.87

5Y Beta

AXSM

0.65

Winner

RNR

0.29

Industry

AXSM

Biotechnology

RNR

Insurance - Reinsurance

P/E Ratio

Winner

AXSM

-67.37

RNR

4.87

Forward P/E

AXSM

333.33

Winner

RNR

9.07

PEG Ratio

AXSM

N/A

RNR

0.05

Dividend Yield

AXSM

N/A

RNR

0.54%

5Y Dividends CAGR

AXSM

N/A

RNR

2.67%

5Y EPS CAGR

AXSM

6.89%

Winner

RNR

41.69%

Debt to Equity

AXSM

344.13%

Winner

RNR

20.24%

Free Cash Flow Yield

AXSM

-0.55%

Winner

RNR

32.85%

AXSM vs RNR - Historical Returns

Returns include dividend reinvestment.

Period	AXSM	RNR
1 month	+10.16%	+0.40%
3 months	+58.67%	+1.31%
6 months	+70.41%	+9.13%
1 year	+143.46%	+22.73%
5 years(CAGR)	+30.05%	+16.83%
10 years(CAGR)	+44.43%	+11.13%
Max(CAGR)	+37.33%	+14.31%

Winner

AXSM

+10.16%

RNR

+0.40%

Winner

AXSM

+58.67%

RNR

+1.31%

Winner

AXSM

+70.41%

RNR

+9.13%

Winner

AXSM

+143.46%

RNR

+22.73%

5Y(CAGR)

Winner

AXSM

+30.05%

RNR

+16.83%

10Y(CAGR)

Winner

AXSM

+44.43%

RNR

+11.13%

Max(CAGR)

Winner

AXSM

+37.33%

RNR

+14.31%

AXSM vs RNR - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	AXSM	RNR
2026	+40.19%	+10.20%
2025	+109.16%	+13.72%
2024	+9.80%	+25.11%
2023	+8.55%	+6.30%
2022	+103.89%	+11.04%
2021	-53.61%	+5.65%
2020	-19.58%	-14.33%
2019	+3756.72%	+51.51%
2018	-48.49%	+11.02%
2017	-13.18%	-6.69%
2016	-44.63%	+22.52%
2015	+6.06%	+19.03%
2014	N/A	+4.54%
2013	N/A	+21.74%
2012	N/A	+12.90%
2011	N/A	+17.99%
2010	N/A	+22.45%
2009	N/A	+6.25%
2008	N/A	-10.77%
2007	N/A	+2.32%
2006	N/A	+34.82%
2005	N/A	-13.39%
2004	N/A	+6.59%
2003	N/A	+25.03%
2002	N/A	+26.99%
2001	N/A	+27.75%
2000	N/A	+99.66%
1999	N/A	+12.49%

AXSM vs RNR Drawdown Comparison

The maximum drawdown for AXSM was -86.65%, occurring on Dec 27, 2018. Recovery took 809 trading sessions.

The maximum drawdown for RNR was -45.66%, occurring on Oct 9, 2008. Recovery took 780 trading sessions.

The current AXSM drawdown is -1.83%. The current RNR drawdown is -4.95%.

Rank	AXSM	RNR
#1	-86.65% Jan 5, 2016 - Mar 25, 2019	-45.66% Oct 2, 2007 - Nov 4, 2010
#2	-81.26% Dec 26, 2019 - Jan 30, 2025	-40.65% Feb 11, 2020 - Jan 13, 2023
#3	-42.70% Sep 16, 2019 - Nov 19, 2019	-33.54% Apr 7, 2004 - Sep 12, 2006
#4	-30.56% Feb 21, 2025 - Nov 6, 2025	-25.09% Feb 12, 2001 - Sep 24, 2001
#5	-18.50% Jan 21, 2026 - Apr 30, 2026	-23.10% Dec 2, 2024 - Feb 3, 2026
#6	-17.63% Mar 25, 2019 - Apr 25, 2019	-21.71% Mar 1, 2017 - Apr 11, 2019
#7	-17.48% Jul 26, 2019 - Sep 16, 2019	-20.76% May 6, 2002 - Oct 10, 2002
#8	-17.26% May 28, 2019 - Jun 20, 2019	-19.90% Feb 9, 2023 - Oct 17, 2023
#9	-11.38% Jun 20, 2019 - Jun 27, 2019	-19.84% Oct 25, 2002 - Apr 22, 2003
#10	-10.33% Nov 24, 2015 - Dec 29, 2015	-17.52% May 20, 2011 - Nov 30, 2011
#11	-9.37% Jul 2, 2019 - Jul 26, 2019	-17.20% Dec 7, 2006 - Jun 22, 2007
#12	-8.83% Dec 4, 2019 - Dec 10, 2019	-17.16% Jan 3, 2001 - Feb 5, 2001
#13	-8.26% Dec 31, 2025 - Jan 20, 2026	-16.04% Nov 5, 2001 - Feb 13, 2002
#14	-7.23% Feb 5, 2025 - Feb 10, 2025	-15.49% Jul 14, 2003 - Dec 1, 2003
#15	-6.21% Nov 28, 2025 - Dec 19, 2025	-14.95% Nov 1, 2023 - Jan 31, 2024