AXSM vs MEDP

Comparison between Axsome Therapeutics Inc (AXSM, Company) and Medpace Holdings Inc (MEDP, Company).

Both AXSM and MEDP are from the Healthcare sector.

5-Year PerformanceAXSM has outperformed MEDP, delivering a return of +31.4% compared to +21.5%

AXSM vs MEDP - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AXSM(COMPANY)	MEDP(COMPANY)
Market Cap	$12B	$12B
Max Drawdown	86.65%	42.87%
Sharpe Ratio	1.93	0.68
5Y Beta	0.69	1.07
Industry	Biotechnology	Diagnostics & Research
P/E Ratio	-63.29	26.06
Forward P/E	333.33	25.19
PEG Ratio	N/A	1.34
5Y EPS CAGR	6.89%	29.42%
Debt to Equity	344.13%	0.00%
Free Cash Flow Yield	-0.59%	5.87%

Market Cap

AXSM

$12B

Winner

MEDP

$12B

Max Drawdown

AXSM

86.65%

Winner

MEDP

42.87%

Sharpe Ratio

Winner

AXSM

1.93

MEDP

0.68

5Y Beta

Winner

AXSM

0.69

MEDP

1.07

Industry

AXSM

Biotechnology

MEDP

Diagnostics & Research

P/E Ratio

Winner

AXSM

-63.29

MEDP

26.06

Forward P/E

AXSM

333.33

Winner

MEDP

25.19

PEG Ratio

AXSM

N/A

MEDP

1.34

5Y EPS CAGR

AXSM

6.89%

Winner

MEDP

29.42%

Debt to Equity

AXSM

344.13%

Winner

MEDP

0.00%

Free Cash Flow Yield

AXSM

-0.59%

Winner

MEDP

5.87%

AXSM vs MEDP - Historical Returns

Returns include dividend reinvestment.

Period	AXSM	MEDP
1 month	+31.96%	-15.46%
3 months	+29.86%	-1.00%
6 months	+71.27%	-28.34%
1 year	+122.69%	+36.63%
5 years(CAGR)	+31.42%	+21.47%
10 years(CAGR)	+36.29%	+32.23%
Max(CAGR)	+36.92%	+32.23%

Winner

AXSM

+31.96%

MEDP

-15.46%

Winner

AXSM

+29.86%

MEDP

-1.00%

Winner

AXSM

+71.27%

MEDP

-28.34%

Winner

AXSM

+122.69%

MEDP

+36.63%

5Y(CAGR)

Winner

AXSM

+31.42%

MEDP

+21.47%

10Y(CAGR)

Winner

AXSM

+36.29%

MEDP

+32.23%

Max(CAGR)

Winner

AXSM

+36.92%

MEDP

+32.23%

AXSM vs MEDP - Annual Returns (2015 - 2026)

Returns include dividend reinvestment.

Year	AXSM	MEDP
2026	+31.69%	-25.79%
2025	+109.16%	+67.78%
2024	+9.80%	+8.72%
2023	+8.55%	+47.17%
2022	+103.89%	-0.89%
2021	-53.61%	+61.91%
2020	-19.58%	+67.77%
2019	+3756.72%	+60.42%
2018	-48.49%	+42.51%
2017	-13.18%	+0.97%
2016	-44.63%	+29.79%
2015	+6.06%	N/A

AXSM vs MEDP Drawdown Comparison

The maximum drawdown for AXSM was -86.65%, occurring on Dec 27, 2018. Recovery took 809 trading sessions.

The maximum drawdown for MEDP was -42.87%, occurring on Apr 27, 2022. Recovery took 264 trading sessions.

The current MEDP drawdown is -31.72%.

Rank	AXSM	MEDP
#1	-86.65% Jan 5, 2016 - Mar 25, 2019	-42.87% Dec 27, 2021 - Jan 13, 2023
#2	-81.26% Dec 26, 2019 - Jan 30, 2025	-41.43% Dec 6, 2016 - Dec 19, 2017
#3	-42.70% Sep 16, 2019 - Nov 19, 2019	-39.47% Feb 25, 2020 - Jul 15, 2020
#4	-30.56% Feb 21, 2025 - Nov 6, 2025	-39.38% Jul 16, 2024 - Jul 22, 2025
#5	-18.50% Jan 21, 2026 - Apr 30, 2026	-36.61% Jan 21, 2026 - Apr 23, 2026
#6	-17.63% Mar 25, 2019 - Apr 25, 2019	-27.23% Jan 23, 2023 - Jun 30, 2023
#7	-17.48% Jul 26, 2019 - Sep 16, 2019	-27.15% Feb 25, 2019 - Jul 30, 2019
#8	-17.26% May 28, 2019 - Jun 20, 2019	-26.31% Sep 18, 2018 - Dec 3, 2018
#9	-11.38% Jun 20, 2019 - Jun 27, 2019	-26.07% Dec 3, 2018 - Jan 31, 2019
#10	-10.33% Nov 24, 2015 - Dec 29, 2015	-19.22% Sep 13, 2023 - Nov 14, 2023
#11	-9.37% Jul 2, 2019 - Jul 26, 2019	-18.41% Sep 17, 2019 - Jan 14, 2020
#12	-8.83% Dec 4, 2019 - Dec 10, 2019	-18.36% Apr 26, 2021 - Sep 3, 2021
#13	-8.26% Dec 31, 2025 - Jan 20, 2026	-18.12% Sep 2, 2020 - Dec 1, 2020
#14	-7.23% Feb 5, 2025 - Feb 10, 2025	-17.99% Feb 26, 2018 - May 7, 2018
#15	-6.21% Nov 28, 2025 - Dec 19, 2025	-12.03% Nov 24, 2025 - Jan 21, 2026