AVDL vs MESO

Comparison between Avadel Pharmaceuticals plc (AVDL, Company) and Mesoblast Ltd (MESO, Company).

Both AVDL and MESO are from the Healthcare sector.

5-Year PerformanceAVDL has outperformed MESO, delivering a return of +19.2% compared to +2.1%

AVDL vs MESO - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AVDL(COMPANY)	MESO(COMPANY)
Market Cap	$2.10B	$2.11B
Max Drawdown	97.50%	95.66%
Sharpe Ratio	2.00	0.33
5Y Beta	N/A	1.38
Industry	Drug Manufacturers - Specialty & Generic	Biotechnology
P/E Ratio	-7003.97	-22.13
Forward P/E	16.86	454.55
PEG Ratio	N/A	0.00
5Y EPS CAGR	N/A	-15.82%
Debt to Equity	0.00%	23.52%
Free Cash Flow Yield	1.63%	-2.48%
P/S Ratio	N/A	32.33
P/B Ratio	N/A	3.71

Market Cap

AVDL

$2.10B

Winner

MESO

$2.11B

Max Drawdown

AVDL

97.50%

Winner

MESO

95.66%

Sharpe Ratio

Winner

AVDL

2.00

MESO

0.33

5Y Beta

AVDL

N/A

MESO

1.38

Industry

AVDL

Drug Manufacturers - Specialty & Generic

MESO

Biotechnology

P/E Ratio

Winner

AVDL

-7003.97

MESO

-22.13

Forward P/E

Winner

AVDL

16.86

MESO

454.55

PEG Ratio

AVDL

N/A

MESO

0.00

5Y EPS CAGR

AVDL

N/A

MESO

-15.82%

Debt to Equity

Winner

AVDL

0.00%

MESO

23.52%

Free Cash Flow Yield

Winner

AVDL

1.63%

MESO

-2.48%

P/S Ratio

AVDL

N/A

MESO

32.33

P/B Ratio

AVDL

N/A

MESO

3.71

AVDL vs MESO - Historical Returns

Returns include dividend reinvestment.

Period	AVDL	MESO
1 month	+0.65%	+4.55%
3 months	+13.00%	+3.74%
6 months	+61.49%	-12.51%
1 year	+142.87%	-0.06%
5 years(CAGR)	+19.21%	+2.06%
10 years(CAGR)	+9.11%	+6.61%
Max(CAGR)	+8.77%	-0.08%

AVDL

+0.65%

Winner

MESO

+4.55%

Winner

AVDL

+13.00%

MESO

+3.74%

Winner

AVDL

+61.49%

MESO

-12.51%

Winner

AVDL

+142.87%

MESO

-0.06%

5Y(CAGR)

Winner

AVDL

+19.21%

MESO

+2.06%

10Y(CAGR)

Winner

AVDL

+9.11%

MESO

+6.61%

Max(CAGR)

Winner

AVDL

+8.77%

MESO

-0.08%

AVDL vs MESO - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	AVDL	MESO
2026	+0.56%	-11.45%
2025	+95.91%	-12.47%
2024	-26.40%	+816.67%
2023	+101.71%	-62.59%
2022	-13.63%	-41.57%
2021	+21.32%	-43.60%
2020	-9.85%	+8.43%
2019	+171.58%	+64.14%
2018	-70.68%	-29.45%
2017	-25.11%	+8.15%
2016	-19.58%	-13.43%
2015	-28.55%	-21.58%
2014	+110.18%	N/A
2013	+147.69%	N/A
2012	-41.62%	N/A
2011	-25.25%	N/A
2010	-9.16%	N/A
2009	+75.27%	N/A
2008	-63.19%	N/A
2007	-68.54%	N/A
2006	+61.89%	N/A
2005	-3.92%	N/A
2004	-28.24%	N/A
2003	+561.48%	N/A
2002	+60.58%	N/A
2001	-58.56%	N/A
2000	+231.05%	N/A
1999	-10.53%	N/A

AVDL vs MESO Drawdown Comparison

The maximum drawdown for AVDL was -97.50%, occurring on May 26, 2022. This drawdown has not yet recovered.

The maximum drawdown for MESO was -95.66%, occurring on Jan 18, 2024. This drawdown has not yet recovered.

The current AVDL drawdown is -49.50%. The current MESO drawdown is -59.41%.

Rank	AVDL	MESO
#1	-97.50% Sep 19, 2003 - May 26, 2022	-95.66% Aug 17, 2020 - Jan 18, 2024
#2	-91.74% Mar 1, 2000 - Jun 4, 2003	-72.61% Apr 26, 2017 - Apr 24, 2020
#3	-60.00% Nov 12, 1999 - Dec 9, 1999	-66.41% Mar 17, 2016 - Apr 11, 2017
#4	-28.57% Dec 9, 1999 - Jan 18, 2000	-46.24% Nov 13, 2015 - Mar 2, 2016
#5	-26.72% Feb 18, 2000 - Feb 29, 2000	-34.96% Aug 10, 2020 - Aug 14, 2020
#6	-26.12% Jul 25, 2003 - Aug 27, 2003	-34.82% Apr 24, 2020 - Aug 5, 2020
#7	-25.00% Jan 18, 2000 - Feb 10, 2000	-16.68% Mar 2, 2016 - Mar 17, 2016
#8	-9.84% Jun 5, 2003 - Jun 23, 2003	-3.53% Apr 20, 2017 - Apr 25, 2017
#9	-7.41% Feb 11, 2000 - Feb 16, 2000	-3.06% Apr 11, 2017 - Apr 18, 2017
#10	-6.59% Jun 27, 2003 - Jul 3, 2003	-1.46% Aug 5, 2020 - Aug 7, 2020
#11	-5.26% Nov 1, 1999 - Nov 12, 1999	-0.80% Apr 18, 2017 - Apr 20, 2017
#12	-4.68% Jul 16, 2003 - Jul 22, 2003	N/A
#13	-2.85% Aug 28, 2003 - Sep 2, 2003	N/A
#14	-2.03% Sep 9, 2003 - Sep 12, 2003	N/A
#15	-1.54% Sep 3, 2003 - Sep 8, 2003	N/A