ASND vs NBIX

Comparison between Ascendis Pharma A/S (ASND, Company) and Neurocrine Biosciences Inc (NBIX, Company).

Both ASND and NBIX are from the Healthcare sector.

5-Year PerformanceASND has outperformed NBIX, delivering a return of +16.5% compared to +12.3%

ASND vs NBIX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ASND(COMPANY)	NBIX(COMPANY)
Market Cap	$18B	$18B
Max Drawdown	61.72%	97.21%
Sharpe Ratio	1.30	1.10
5Y Beta	0.45	0.79
Industry	Biotechnology	Drug Manufacturers - Specialty & Generic
P/E Ratio	31.05	26.64
Forward P/E	17.33	24.57
PEG Ratio	N/A	0.22
5Y EPS CAGR	N/A	9.25%
Debt to Equity	183.75%	0.00%
Free Cash Flow Yield	0.28%	4.61%
P/S Ratio	21.00	5.78
P/B Ratio	32.72	5.13

Market Cap

ASND

$18B

Winner

NBIX

$18B

Max Drawdown

Winner

ASND

61.72%

NBIX

97.21%

Sharpe Ratio

Winner

ASND

1.30

NBIX

1.10

5Y Beta

Winner

ASND

0.45

NBIX

0.79

Industry

ASND

Biotechnology

NBIX

Drug Manufacturers - Specialty & Generic

P/E Ratio

ASND

31.05

Winner

NBIX

26.64

Forward P/E

Winner

ASND

17.33

NBIX

24.57

PEG Ratio

ASND

N/A

NBIX

0.22

5Y EPS CAGR

ASND

N/A

NBIX

9.25%

Debt to Equity

ASND

183.75%

Winner

NBIX

0.00%

Free Cash Flow Yield

ASND

0.28%

Winner

NBIX

4.61%

P/S Ratio

ASND

21.00

Winner

NBIX

5.78

P/B Ratio

ASND

32.72

Winner

NBIX

5.13

ASND vs NBIX - Historical Returns

Returns include dividend reinvestment.

Period	ASND	NBIX
1 month	+28.91%	+10.10%
3 months	+13.03%	+37.41%
6 months	+33.23%	+30.43%
1 year	+53.24%	+31.27%
5 years(CAGR)	+16.49%	+12.32%
10 years(CAGR)	+35.61%	+13.80%
Max(CAGR)	+26.21%	+12.87%

Winner

ASND

+28.91%

NBIX

+10.10%

ASND

+13.03%

Winner

NBIX

+37.41%

Winner

ASND

+33.23%

NBIX

+30.43%

Winner

ASND

+53.24%

NBIX

+31.27%

5Y(CAGR)

Winner

ASND

+16.49%

NBIX

+12.32%

10Y(CAGR)

Winner

ASND

+35.61%

NBIX

+13.80%

Max(CAGR)

Winner

ASND

+26.21%

NBIX

+12.87%

ASND vs NBIX - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	ASND	NBIX
2026	+26.80%	+25.97%
2025	+54.52%	+2.88%
2024	+7.95%	+3.62%
2023	+4.33%	+9.73%
2022	-10.03%	+35.01%
2021	-18.71%	-11.16%
2020	+18.17%	-11.50%
2019	+114.56%	+53.36%
2018	+57.41%	-9.95%
2017	+101.21%	+100.70%
2016	+12.26%	-26.07%
2015	-2.71%	+147.68%
2014	N/A	+133.93%
2013	N/A	+14.74%
2012	N/A	-12.51%
2011	N/A	+10.82%
2010	N/A	+184.01%
2009	N/A	-16.82%
2008	N/A	-29.20%
2007	N/A	-55.79%
2006	N/A	-83.61%
2005	N/A	+27.97%
2004	N/A	-11.17%
2003	N/A	+20.11%
2002	N/A	-9.71%
2001	N/A	+59.40%
2000	N/A	+31.89%
1999	N/A	+253.57%

ASND vs NBIX Drawdown Comparison

The maximum drawdown for ASND was -61.72%, occurring on Apr 28, 2023. Recovery took 1163 trading sessions.

The maximum drawdown for NBIX was -97.21%, occurring on Nov 12, 2009. Recovery took 2931 trading sessions.

The current ASND drawdown is -2.43%. The current NBIX drawdown is -1.91%.

Rank	ASND	NBIX
#1	-61.72% Dec 14, 2020 - Aug 4, 2025	-97.21% Mar 15, 2006 - Nov 2, 2017
#2	-42.92% Jul 16, 2015 - Feb 1, 2017	-66.15% Mar 3, 2000 - Nov 20, 2001
#3	-33.15% Feb 20, 2020 - May 20, 2020	-54.12% Dec 24, 2001 - Jun 5, 2003
#4	-30.77% Jun 3, 2019 - Dec 26, 2019	-50.71% Apr 27, 2004 - Feb 27, 2006
#5	-27.69% Aug 27, 2018 - Mar 4, 2019	-46.39% Jul 15, 2020 - Jan 17, 2024
#6	-24.67% Mar 2, 2017 - Sep 22, 2017	-45.71% Sep 4, 2018 - Jun 19, 2020
#7	-24.09% Apr 23, 2015 - Jul 15, 2015	-42.89% Jan 30, 2025 - Nov 5, 2025
#8	-17.62% Apr 14, 2026 - Jun 25, 2026	-28.57% Jan 21, 2000 - Feb 16, 2000
#9	-17.60% Mar 13, 2019 - Jun 3, 2019	-27.12% Aug 1, 2024 - Jan 30, 2025
#10	-13.95% Mar 12, 2018 - May 25, 2018	-22.86% Dec 2, 1999 - Dec 13, 1999
#11	-13.92% Jun 23, 2020 - Oct 2, 2020	-21.32% Jun 16, 2003 - Jan 23, 2004
#12	-13.85% Oct 2, 2017 - Dec 5, 2017	-20.90% Dec 10, 2025 - May 12, 2026
#13	-13.50% Nov 4, 2020 - Dec 8, 2020	-19.01% Dec 29, 1999 - Jan 10, 2000
#14	-13.25% Jan 29, 2015 - Apr 21, 2015	-18.53% Mar 9, 2018 - May 15, 2018
#15	-12.96% May 29, 2018 - Aug 24, 2018	-13.74% Jan 26, 2004 - Mar 4, 2004