ARWR vs SPY
Comparison between Arrowhead Pharmaceuticals Inc (ARWR, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).
5-Year PerformanceSPY has outperformed ARWR, delivering a return of +13.3% compared to +1.8%
ARWR vs SPY - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap / Net Assets
ARWR
$11B
Winner
SPY
$652B
Expense Ratio
ARWR
N/A
SPY
0.09%
Max Drawdown
ARWR
99.24%
Winner
SPY
56.47%
Sharpe Ratio
Winner
ARWR
2.89
SPY
2.07
5Y Beta
ARWR
1.66
Winner
SPY
1.00
Industry
ARWR
Biotechnology
SPY
N/A
P/E Ratio
ARWR
54.06
Winner
SPY
28.24
Forward P/E
ARWR
97.09
Winner
SPY
21.85
PEG Ratio
ARWR
-1.32
SPY
N/A
5Y Dividends CAGR
ARWR
N/A
SPY
5.43%
5Y EPS CAGR
ARWR
N/A
SPY
25.79%
Debt to Equity
Winner
ARWR
0.00%
SPY
22.35%
Free Cash Flow Yield
ARWR
2.96%
SPY
N/A
P/S Ratio
ARWR
10.16
Winner
SPY
3.55
P/B Ratio
ARWR
18.46
Winner
SPY
5.29
ARWR vs SPY - Historical Returns
Returns include dividend reinvestment.
1M
Winner
ARWR
+12.94%
SPY
+9.11%
3M
Winner
ARWR
+16.04%
SPY
+6.59%
6M
Winner
ARWR
+85.29%
SPY
+10.56%
1Y
Winner
ARWR
+448.60%
SPY
+32.04%
5Y(CAGR)
ARWR
+1.83%
Winner
SPY
+13.35%
10Y(CAGR)
Winner
ARWR
+28.87%
SPY
+15.49%
Max(CAGR)
ARWR
+0.82%
Winner
SPY
+8.50%
ARWR vs SPY - Annual Returns (1999 - 2026)
Returns include dividend reinvestment.
| Year | ARWR | SPY |
|---|---|---|
| 2026 | +7.23% | +8.27% |
| 2025 | +237.86% | +18.00% |
| 2024 | -39.37% | +25.59% |
| 2023 | -20.54% | +26.72% |
| 2022 | -42.03% | -18.64% |
| 2021 | -11.40% | +30.52% |
| 2020 | +21.56% | +17.28% |
| 2019 | +383.46% | +31.09% |
| 2018 | +233.87% | -5.24% |
| 2017 | +119.05% | +20.78% |
| 2016 | -74.08% | +13.59% |
| 2015 | -20.23% | +1.31% |
| 2014 | -28.42% | +14.56% |
| 2013 | +416.67% | +29.00% |
| 2012 | -48.18% | +14.17% |
| 2011 | -58.10% | +0.85% |
| 2010 | +65.74% | +13.14% |
| 2009 | -49.52% | +22.67% |
| 2008 | -74.08% | -36.25% |
| 2007 | -14.09% | +5.32% |
| 2006 | +8.42% | +13.85% |
| 2005 | +6.25% | +5.32% |
| 2004 | +232.31% | +10.75% |
| 2003 | +100.00% | +24.18% |
| 2002 | +0.00% | -22.42% |
| 2001 | -83.33% | -10.13% |
| 2000 | +0.00% | -8.84% |
| 1999 | -33.33% | +8.61% |
ARWR vs SPY Drawdown Comparison
The maximum drawdown for ARWR was -99.24%, occurring on Dec 16, 2016. This drawdown has not yet recovered.
The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.
The current ARWR drawdown is -55.27%.
| Rank | ARWR | SPY |
|---|---|---|
| #1 | -99.24% Mar 3, 2000 - Dec 16, 2016 | -55.20% Oct 9, 2007 - Aug 16, 2012 |
| #2 | -38.83% Nov 1, 1999 - Jan 19, 2000 | -47.50% Mar 24, 2000 - Oct 26, 2006 |
| #3 | -31.58% Feb 4, 2000 - Mar 3, 2000 | -33.70% Feb 19, 2020 - Aug 10, 2020 |
| #4 | -13.42% Jan 19, 2000 - Feb 4, 2000 | -24.50% Jan 3, 2022 - Dec 13, 2023 |
| #5 | N/A | -19.34% Sep 20, 2018 - Apr 12, 2019 |
| #6 | N/A | -18.76% Feb 19, 2025 - Jun 26, 2025 |
| #7 | N/A | -13.02% Jul 20, 2015 - Apr 18, 2016 |
| #8 | N/A | -10.10% Jan 26, 2018 - Aug 6, 2018 |
| #9 | N/A | -9.44% Sep 2, 2020 - Nov 11, 2020 |
| #10 | N/A | -9.30% Jan 19, 2000 - Mar 17, 2000 |
| #11 | N/A | -9.05% Jul 19, 2007 - Oct 5, 2007 |
| #12 | N/A | -8.88% Jan 27, 2026 - Apr 14, 2026 |
| #13 | N/A | -8.41% Jul 16, 2024 - Sep 19, 2024 |
| #14 | N/A | -7.35% Sep 14, 2012 - Jan 2, 2013 |
| #15 | N/A | -7.27% Sep 18, 2014 - Oct 31, 2014 |
Correlation
Correlation between ARWR and SPY is 0.23 which considered as a very weak or no correlation - the stocks move independently of each other.
0.23
-101
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