ARWR vs PEN

Comparison between Arrowhead Pharmaceuticals Inc (ARWR, Company) and Penumbra Inc (PEN, Company).

Both ARWR and PEN are from the Healthcare sector.

5-Year PerformanceARWR has outperformed PEN, delivering a return of +4.6% compared to +3.7%

ARWR vs PEN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ARWR(COMPANY)	PEN(COMPANY)
Market Cap	$12B	$12B
Max Drawdown	99.24%	62.64%
Sharpe Ratio	2.83	0.99
5Y Beta	1.66	0.53
Industry	Biotechnology	Medical Devices
P/E Ratio	-41.00	75.61
Forward P/E	111.11	62.50
PEG Ratio	-0.82	4.07
5Y EPS CAGR	15.23%	46.16%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-0.41%	1.71%
P/S Ratio	20.09	8.56
P/B Ratio	17.09	8.47

Market Cap

Winner

ARWR

$12B

PEN

$12B

Max Drawdown

ARWR

99.24%

Winner

PEN

62.64%

Sharpe Ratio

Winner

ARWR

2.83

PEN

0.99

5Y Beta

ARWR

1.66

Winner

PEN

0.53

Industry

ARWR

Biotechnology

PEN

Medical Devices

P/E Ratio

Winner

ARWR

-41.00

PEN

75.61

Forward P/E

ARWR

111.11

Winner

PEN

62.50

PEG Ratio

Winner

ARWR

-0.82

PEN

4.07

5Y EPS CAGR

ARWR

15.23%

Winner

PEN

46.16%

Debt to Equity

ARWR

0.00%

PEN

0.00%

Free Cash Flow Yield

ARWR

-0.41%

Winner

PEN

1.71%

P/S Ratio

ARWR

20.09

Winner

PEN

8.56

P/B Ratio

ARWR

17.09

Winner

PEN

8.47

ARWR vs PEN - Historical Returns

Returns include dividend reinvestment.

Period	ARWR	PEN
1 month	+7.25%	+0.75%
3 months	+15.82%	-3.38%
6 months	+27.67%	-11.28%
1 year	+426.45%	+38.47%
5 years(CAGR)	+4.60%	+3.65%
10 years(CAGR)	+31.25%	+17.97%
Max(CAGR)	+1.43%	+20.73%

Winner

ARWR

+7.25%

PEN

+0.75%

Winner

ARWR

+15.82%

PEN

-3.38%

Winner

ARWR

+27.67%

PEN

-11.28%

Winner

ARWR

+426.45%

PEN

+38.47%

5Y(CAGR)

Winner

ARWR

+4.60%

PEN

+3.65%

10Y(CAGR)

Winner

ARWR

+31.25%

PEN

+17.97%

Max(CAGR)

ARWR

+1.43%

Winner

PEN

+20.73%

ARWR vs PEN - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	ARWR	PEN
2026	+26.27%	+3.01%
2025	+237.86%	+29.55%
2024	-39.37%	-2.98%
2023	-20.54%	+13.72%
2022	-42.03%	-21.66%
2021	-11.40%	+63.62%
2020	+21.56%	+6.84%
2019	+383.46%	+33.48%
2018	+233.87%	+35.25%
2017	+119.05%	+46.92%
2016	-74.08%	+14.52%
2015	-20.23%	+30.29%
2014	-28.42%	N/A
2013	+416.67%	N/A
2012	-48.18%	N/A
2011	-58.10%	N/A
2010	+65.74%	N/A
2009	-49.52%	N/A
2008	-74.08%	N/A
2007	-14.09%	N/A
2006	+8.42%	N/A
2005	+6.25%	N/A
2004	+232.31%	N/A
2003	+100.00%	N/A
2002	+0.00%	N/A
2001	-83.33%	N/A
2000	+0.00%	N/A
1999	-33.33%	N/A

ARWR vs PEN Drawdown Comparison

The maximum drawdown for ARWR was -99.24%, occurring on Dec 16, 2016. This drawdown has not yet recovered.

The maximum drawdown for PEN was -62.64%, occurring on Jun 16, 2022. Recovery took 511 trading sessions.

The current ARWR drawdown is -47.32%. The current PEN drawdown is -11.32%.

Rank	ARWR	PEN
#1	-99.24% Mar 3, 2000 - Dec 16, 2016	-62.64% Apr 28, 2021 - May 9, 2023
#2	-38.83% Nov 1, 1999 - Jan 19, 2000	-52.44% Jun 30, 2023 - Jan 15, 2026
#3	-31.58% Feb 4, 2000 - Mar 3, 2000	-35.86% Nov 12, 2020 - Feb 9, 2021
#4	-13.42% Jan 19, 2000 - Feb 4, 2000	-35.83% Feb 19, 2020 - Jul 8, 2020
#5	N/A	-31.65% Jun 6, 2018 - Jun 14, 2019
#6	N/A	-28.12% Jul 24, 2019 - Feb 11, 2020
#7	N/A	-26.97% Nov 9, 2017 - Mar 6, 2018
#8	N/A	-26.12% Sep 22, 2016 - Feb 21, 2017
#9	N/A	-24.61% Jan 4, 2016 - Jun 6, 2016
#10	N/A	-21.70% Aug 13, 2020 - Oct 27, 2020
#11	N/A	-13.42% Dec 1, 2015 - Dec 11, 2015
#12	N/A	-12.79% Mar 1, 2021 - Apr 23, 2021
#13	N/A	-12.45% Oct 8, 2015 - Nov 13, 2015
#14	N/A	-12.23% Jan 27, 2026 - Jun 29, 2026
#15	N/A	-11.94% Jun 23, 2017 - Oct 2, 2017