ARWR vs AFG

Comparison between Arrowhead Pharmaceuticals Inc (ARWR, Company) and American Financial Group Inc (AFG, Company).

ARWR is from the Healthcare sector, while AFG is from the Financial Services sector.

5-Year PerformanceAFG has outperformed ARWR, delivering a return of +11.3% compared to +1.7%

ARWR vs AFG - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ARWR(COMPANY)	AFG(COMPANY)
Market Cap	$11B	$11B
Max Drawdown	99.24%	64.27%
Sharpe Ratio	2.81	0.68
5Y Beta	1.65	0.47
Industry	Biotechnology	Insurance - Property & Casualty
P/E Ratio	-36.51	12.67
Forward P/E	111.11	11.53
PEG Ratio	-0.73	1.18
Dividend Yield	N/A	2.52%
5Y Dividends CAGR	N/A	14.40%
5Y EPS CAGR	15.23%	-8.90%
Debt to Equity	0.00%	38.91%
Free Cash Flow Yield	-0.46%	15.00%

Market Cap

Winner

ARWR

$11B

AFG

$11B

Max Drawdown

ARWR

99.24%

Winner

AFG

64.27%

Sharpe Ratio

Winner

ARWR

2.81

AFG

0.68

5Y Beta

ARWR

1.65

Winner

AFG

0.47

Industry

ARWR

Biotechnology

AFG

Insurance - Property & Casualty

P/E Ratio

Winner

ARWR

-36.51

AFG

12.67

Forward P/E

ARWR

111.11

Winner

AFG

11.53

PEG Ratio

Winner

ARWR

-0.73

AFG

1.18

Dividend Yield

ARWR

N/A

AFG

2.52%

5Y Dividends CAGR

ARWR

N/A

AFG

14.40%

5Y EPS CAGR

Winner

ARWR

15.23%

AFG

-8.90%

Debt to Equity

Winner

ARWR

0.00%

AFG

38.91%

Free Cash Flow Yield

ARWR

-0.46%

Winner

AFG

15.00%

ARWR vs AFG - Historical Returns

Returns include dividend reinvestment.

Period	ARWR	AFG
1 month	+7.32%	+3.13%
3 months	+24.85%	+1.15%
6 months	+36.87%	-0.20%
1 year	+413.92%	+14.02%
5 years(CAGR)	+1.65%	+11.31%
10 years(CAGR)	+29.65%	+14.40%
Max(CAGR)	+1.14%	+12.30%

Winner

ARWR

+7.32%

AFG

+3.13%

Winner

ARWR

+24.85%

AFG

+1.15%

Winner

ARWR

+36.87%

AFG

-0.20%

Winner

ARWR

+413.92%

AFG

+14.02%

5Y(CAGR)

ARWR

+1.65%

Winner

AFG

+11.31%

10Y(CAGR)

Winner

ARWR

+29.65%

AFG

+14.40%

Max(CAGR)

ARWR

+1.14%

Winner

AFG

+12.30%

ARWR vs AFG - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	ARWR	AFG
2026	+16.52%	+1.63%
2025	+237.86%	+6.63%
2024	-39.37%	+23.21%
2023	-20.54%	-7.29%
2022	-42.03%	+12.38%
2021	-11.40%	+100.41%
2020	+21.56%	-17.32%
2019	+383.46%	+28.58%
2018	+233.87%	-11.62%
2017	+119.05%	+29.61%
2016	-74.08%	+28.46%
2015	-20.23%	+23.23%
2014	-28.42%	+11.05%
2013	+416.67%	+49.47%
2012	-48.18%	+8.30%
2011	-58.10%	+14.20%
2010	+65.74%	+29.55%
2009	-49.52%	+9.06%
2008	-74.08%	-18.23%
2007	-14.09%	-19.89%
2006	+8.42%	+42.58%
2005	+6.25%	+25.44%
2004	+232.31%	+20.43%
2003	+100.00%	+16.50%
2002	+0.00%	-1.88%
2001	-83.33%	-3.80%
2000	+0.00%	+9.32%
1999	-33.33%	-8.43%

ARWR vs AFG Drawdown Comparison

The maximum drawdown for ARWR was -99.24%, occurring on Dec 16, 2016. This drawdown has not yet recovered.

The maximum drawdown for AFG was -62.93%, occurring on Mar 9, 2009. Recovery took 999 trading sessions.

The current ARWR drawdown is -51.39%. The current AFG drawdown is -5.96%.

Rank	ARWR	AFG
#1	-99.24% Mar 3, 2000 - Dec 16, 2016	-62.93% Feb 21, 2007 - Feb 7, 2011
#2	-38.83% Nov 1, 1999 - Jan 19, 2000	-58.98% Feb 11, 2020 - Feb 22, 2021
#3	-31.58% Feb 4, 2000 - Mar 3, 2000	-38.10% Apr 19, 2002 - Feb 2, 2004
#4	-13.42% Jan 19, 2000 - Feb 4, 2000	-38.06% Jul 13, 2001 - Apr 17, 2002
#5	N/A	-37.71% Nov 5, 1999 - Feb 5, 2001
#6	N/A	-26.46% Feb 1, 2018 - Nov 27, 2019
#7	N/A	-23.79% Nov 10, 2022 - Mar 25, 2024
#8	N/A	-22.41% Feb 5, 2001 - Jun 11, 2001
#9	N/A	-19.87% Nov 25, 2024 - Sep 24, 2025
#10	N/A	-16.15% Jun 7, 2022 - Oct 28, 2022
#11	N/A	-16.07% Jul 7, 2011 - Oct 24, 2011
#12	N/A	-13.18% Oct 3, 2025 - Mar 20, 2026
#13	N/A	-12.24% Nov 16, 2004 - May 4, 2005
#14	N/A	-12.05% Mar 27, 2024 - Sep 9, 2024
#15	N/A	-11.76% Dec 4, 2015 - Jun 23, 2016