APLS vs TVTX

Comparison between Apellis Pharmaceuticals Inc (APLS, Company) and Travere Therapeutics Inc (TVTX, Company).

Both APLS and TVTX are from the Healthcare sector.

5-Year PerformanceTVTX has outperformed APLS, delivering a return of +32.7% compared to -1.5%

APLS vs TVTX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	APLS(COMPANY)	TVTX(COMPANY)
Market Cap	$5.25B	$5.24B
Max Drawdown	82.47%	85.43%
Sharpe Ratio	1.03	2.05
5Y Beta	N/A	1.28
Industry	Biotechnology	Biotechnology
P/E Ratio	39.02	-249.63
Forward P/E	46.30	77.52
5Y EPS CAGR	N/A	-44.12%
Debt to Equity	22.59%	0.00%
Free Cash Flow Yield	0.71%	0.74%
P/S Ratio	N/A	9.84
P/B Ratio	N/A	53.75

Market Cap

Winner

APLS

$5.25B

TVTX

$5.24B

Max Drawdown

Winner

APLS

82.47%

TVTX

85.43%

Sharpe Ratio

APLS

1.03

Winner

TVTX

2.05

5Y Beta

APLS

N/A

TVTX

1.28

Industry

APLS

Biotechnology

TVTX

Biotechnology

P/E Ratio

APLS

39.02

Winner

TVTX

-249.63

Forward P/E

Winner

APLS

46.30

TVTX

77.52

5Y EPS CAGR

APLS

N/A

TVTX

-44.12%

Debt to Equity

APLS

22.59%

Winner

TVTX

0.00%

Free Cash Flow Yield

APLS

0.71%

Winner

TVTX

0.74%

P/S Ratio

APLS

N/A

TVTX

9.84

P/B Ratio

APLS

N/A

TVTX

53.75

APLS vs TVTX - Historical Returns

Returns include dividend reinvestment.

Period	APLS	TVTX
1 month	+0.44%	+2.67%
3 months	+89.08%	+45.90%
6 months	+101.82%	+100.28%
1 year	+145.69%	+257.65%
5 years(CAGR)	-1.50%	+32.72%
10 years(CAGR)	+13.44%	+12.28%
Max(CAGR)	+13.44%	+30.35%

APLS

+0.44%

Winner

TVTX

+2.67%

Winner

APLS

+89.08%

TVTX

+45.90%

Winner

APLS

+101.82%

TVTX

+100.28%

APLS

+145.69%

Winner

TVTX

+257.65%

5Y(CAGR)

APLS

-1.50%

Winner

TVTX

+32.72%

10Y(CAGR)

Winner

APLS

+13.44%

TVTX

+12.28%

Max(CAGR)

APLS

+13.44%

Winner

TVTX

+30.35%

APLS vs TVTX - Annual Returns (2012 - 2026)

Returns include dividend reinvestment.

Year	APLS	TVTX
2026	+58.66%	+43.17%
2025	-24.25%	+101.42%
2024	-47.92%	+82.22%
2023	+19.05%	-56.49%
2022	+6.03%	-31.27%
2021	-13.39%	+14.96%
2020	+83.54%	+96.50%
2019	+124.82%	-37.36%
2018	-36.53%	+0.71%
2017	+54.67%	+14.20%
2016	N/A	+0.21%
2015	N/A	+52.25%
2014	N/A	+53.00%
2013	N/A	+118.75%
2012	N/A	+123.33%

APLS vs TVTX Drawdown Comparison

The maximum drawdown for APLS was -82.47%, occurring on May 15, 2025. This drawdown has not yet recovered.

The maximum drawdown for TVTX was -85.43%, occurring on Apr 26, 2024. Recovery took 2583 trading sessions.

The current APLS drawdown is -56.03%. The current TVTX drawdown is -4.15%.

Rank	APLS	TVTX
#1	-82.47% Jun 13, 2023 - May 15, 2025	-85.43% Aug 5, 2015 - Nov 11, 2025
#2	-61.77% Apr 16, 2018 - Sep 5, 2019	-65.37% Apr 2, 2014 - Mar 30, 2015
#3	-59.60% Feb 10, 2020 - Nov 20, 2020	-62.29% Dec 17, 2012 - May 3, 2013
#4	-55.99% Jul 2, 2021 - Apr 3, 2023	-48.63% May 10, 2013 - Jan 10, 2014
#5	-43.83% Jan 4, 2018 - Mar 14, 2018	-46.81% Dec 3, 2012 - Dec 17, 2012
#6	-31.32% Sep 6, 2019 - Jan 7, 2020	-33.49% Dec 24, 2025 - Apr 14, 2026
#7	-28.91% Jan 8, 2021 - Jun 1, 2021	-25.27% Jan 17, 2014 - Feb 13, 2014
#8	-21.52% Mar 16, 2018 - Apr 11, 2018	-12.97% Apr 24, 2015 - May 15, 2015
#9	-12.47% Dec 11, 2017 - Dec 21, 2017	-12.42% Mar 10, 2014 - Mar 25, 2014
#10	-8.62% May 5, 2023 - Jun 13, 2023	-11.81% Jul 16, 2015 - Aug 5, 2015
#11	-8.38% Dec 8, 2020 - Dec 15, 2020	-10.05% May 27, 2026 - Jun 9, 2026
#12	-8.03% Jun 14, 2021 - Jul 1, 2021	-9.24% Feb 21, 2014 - Mar 10, 2014
#13	-6.75% Apr 24, 2023 - May 5, 2023	-8.04% Jun 5, 2015 - Jun 18, 2015
#14	-6.20% Jan 21, 2020 - Feb 3, 2020	-7.95% Apr 14, 2026 - May 1, 2026
#15	-5.53% Nov 13, 2017 - Dec 8, 2017	-7.37% Feb 13, 2014 - Feb 20, 2014