APLS vs CAI

Comparison between Apellis Pharmaceuticals Inc (APLS, Company) and Caris Life Sciences Inc - Class A (CAI, Company).

Both APLS and CAI are from the Healthcare sector.

APLS vs CAI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	APLS(COMPANY)	CAI(COMPANY)
Market Cap	$5.25B	$5.22B
Max Drawdown	82.47%	62.98%
Sharpe Ratio	1.03	-0.44
5Y Beta	N/A	1.48
Industry	Biotechnology	Biotechnology
P/E Ratio	39.02	-76.64
Forward P/E	46.30	45.45
Debt to Equity	22.59%	64.29%
Free Cash Flow Yield	0.71%	2.36%
P/S Ratio	N/A	5.75
P/B Ratio	N/A	8.80

Market Cap

Winner

APLS

$5.25B

CAI

$5.22B

Max Drawdown

APLS

82.47%

Winner

CAI

62.98%

Sharpe Ratio

Winner

APLS

1.03

CAI

-0.44

5Y Beta

APLS

N/A

CAI

1.48

Industry

APLS

Biotechnology

CAI

Biotechnology

P/E Ratio

APLS

39.02

Winner

CAI

-76.64

Forward P/E

APLS

46.30

Winner

CAI

45.45

Debt to Equity

Winner

APLS

22.59%

CAI

64.29%

Free Cash Flow Yield

APLS

0.71%

Winner

CAI

2.36%

P/S Ratio

APLS

N/A

CAI

5.75

P/B Ratio

APLS

N/A

CAI

8.80

APLS vs CAI - Historical Returns

Returns include dividend reinvestment.

Period	APLS	CAI
1 month	+0.44%	+13.18%
3 months	+89.08%	-8.62%
6 months	+101.82%	-37.14%
1 year	+145.69%	-32.15%
5 years(CAGR)	-1.50%	N/A
10 years(CAGR)	+13.44%	N/A
Max(CAGR)	+13.44%	-36.77%

APLS

+0.44%

Winner

CAI

+13.18%

Winner

APLS

+89.08%

CAI

-8.62%

Winner

APLS

+101.82%

CAI

-37.14%

Winner

APLS

+145.69%

CAI

-32.15%

5Y(CAGR)

APLS

-1.50%

CAI

N/A

10Y(CAGR)

APLS

+13.44%

CAI

N/A

Max(CAGR)

Winner

APLS

+13.44%

CAI

-36.77%

APLS vs CAI - Annual Returns (2017 - 2026)

Returns include dividend reinvestment.

Year	APLS	CAI
2026	+58.66%	-34.77%
2025	-24.25%	-3.64%
2024	-47.92%	N/A
2023	+19.05%	N/A
2022	+6.03%	N/A
2021	-13.39%	N/A
2020	+83.54%	N/A
2019	+124.82%	N/A
2018	-36.53%	N/A
2017	+54.67%	N/A

APLS vs CAI Drawdown Comparison

The maximum drawdown for APLS was -82.47%, occurring on May 15, 2025. This drawdown has not yet recovered.

The maximum drawdown for CAI was -62.98%, occurring on May 15, 2026. This drawdown has not yet recovered.

The current APLS drawdown is -56.03%. The current CAI drawdown is -55.22%.

Rank	APLS	CAI
#1	-82.47% Jun 13, 2023 - May 15, 2025	-62.98% Aug 22, 2025 - May 15, 2026
#2	-61.77% Apr 16, 2018 - Sep 5, 2019	-13.82% Jul 16, 2025 - Aug 12, 2025
#3	-59.60% Feb 10, 2020 - Nov 20, 2020	-7.36% Jun 18, 2025 - Jul 15, 2025
#4	-55.99% Jul 2, 2021 - Apr 3, 2023	-5.19% Aug 14, 2025 - Aug 21, 2025
#5	-43.83% Jan 4, 2018 - Mar 14, 2018	N/A
#6	-31.32% Sep 6, 2019 - Jan 7, 2020	N/A
#7	-28.91% Jan 8, 2021 - Jun 1, 2021	N/A
#8	-21.52% Mar 16, 2018 - Apr 11, 2018	N/A
#9	-12.47% Dec 11, 2017 - Dec 21, 2017	N/A
#10	-8.62% May 5, 2023 - Jun 13, 2023	N/A
#11	-8.38% Dec 8, 2020 - Dec 15, 2020	N/A
#12	-8.03% Jun 14, 2021 - Jul 1, 2021	N/A
#13	-6.75% Apr 24, 2023 - May 5, 2023	N/A
#14	-6.20% Jan 21, 2020 - Feb 3, 2020	N/A
#15	-5.53% Nov 13, 2017 - Dec 8, 2017	N/A

Correlation

Correlation between APLS and CAI is -0.57 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.57

-101