APLS vs CADE

Comparison between Apellis Pharmaceuticals Inc (APLS, Company) and Cadence Bank (CADE, Company).

APLS is from the Healthcare sector, while CADE is from the Financial Services sector.

5-Year PerformanceCADE has outperformed APLS, delivering a return of +13.6% compared to -1.5%

APLS vs CADE - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	APLS(COMPANY)	CADE(COMPANY)
Market Cap	$5.25B	$5.25B
Max Drawdown	82.47%	72.15%
Sharpe Ratio	1.03	0.73
Industry	Biotechnology	Banks - Regional
P/E Ratio	39.02	11.54
Forward P/E	46.30	11.86
Dividend Yield	N/A	2.57%
5Y Dividends CAGR	N/A	14.15%
Debt to Equity	22.59%	6.52%
Free Cash Flow Yield	0.71%	2.78%
P/S Ratio	4.75	N/A
P/B Ratio	12.66	N/A

Market Cap

APLS

$5.25B

Winner

CADE

$5.25B

Max Drawdown

APLS

82.47%

Winner

CADE

72.15%

Sharpe Ratio

Winner

APLS

1.03

CADE

0.73

Industry

APLS

Biotechnology

CADE

Banks - Regional

P/E Ratio

APLS

39.02

Winner

CADE

11.54

Forward P/E

APLS

46.30

Winner

CADE

11.86

Dividend Yield

APLS

N/A

CADE

2.57%

5Y Dividends CAGR

APLS

N/A

CADE

14.15%

Debt to Equity

APLS

22.59%

Winner

CADE

6.52%

Free Cash Flow Yield

APLS

0.71%

Winner

CADE

2.78%

P/S Ratio

APLS

4.75

CADE

N/A

P/B Ratio

APLS

12.66

CADE

N/A

APLS vs CADE - Historical Returns

Returns include dividend reinvestment.

Period	APLS	CADE
1 month	+0.44%	-1.59%
3 months	+89.08%	+14.30%
6 months	+101.82%	+22.11%
1 year	+145.69%	+24.33%
5 years(CAGR)	-1.50%	+13.64%
10 years(CAGR)	+13.44%	+10.88%
Max(CAGR)	+13.44%	+6.58%

Winner

APLS

+0.44%

CADE

-1.59%

Winner

APLS

+89.08%

CADE

+14.30%

Winner

APLS

+101.82%

CADE

+22.11%

Winner

APLS

+145.69%

CADE

+24.33%

5Y(CAGR)

APLS

-1.50%

Winner

CADE

+13.64%

10Y(CAGR)

Winner

APLS

+13.44%

CADE

+10.88%

Max(CAGR)

Winner

APLS

+13.44%

CADE

+6.58%

APLS vs CADE - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	APLS	CADE
2026	+58.66%	-1.77%
2025	-24.25%	+31.27%
2024	-47.92%	+20.85%
2023	+19.05%	+26.70%
2022	+6.03%	-16.17%
2021	-13.39%	+15.89%
2020	+83.54%	-10.03%
2019	+124.82%	+20.86%
2018	-36.53%	-15.66%
2017	+54.67%	+2.71%
2016	N/A	+36.28%
2015	N/A	+9.39%
2014	N/A	-8.49%
2013	N/A	+70.47%
2012	N/A	+27.58%
2011	N/A	-32.59%
2010	N/A	-28.90%
2009	N/A	+3.27%
2008	N/A	+3.71%
2007	N/A	-11.16%
2006	N/A	+22.05%
2005	N/A	-5.02%
2004	N/A	+6.91%
2003	N/A	+24.28%
2002	N/A	+22.78%
2001	N/A	+32.58%
2000	N/A	-20.38%
1999	N/A	-5.05%

APLS vs CADE Drawdown Comparison

The maximum drawdown for APLS was -82.47%, occurring on May 15, 2025. This drawdown has not yet recovered.

The maximum drawdown for CADE was -68.79%, occurring on Oct 3, 2011. Recovery took 1700 trading sessions.

The current APLS drawdown is -56.03%. The current CADE drawdown is -8.62%.

Rank	APLS	CADE
#1	-82.47% Jun 13, 2023 - May 15, 2025	-68.79% Sep 19, 2008 - Jun 23, 2015
#2	-61.77% Apr 16, 2018 - Sep 5, 2019	-47.64% Sep 5, 2018 - Mar 8, 2021
#3	-59.60% Feb 10, 2020 - Nov 20, 2020	-45.92% Jan 14, 2022 - Jul 16, 2024
#4	-55.99% Jul 2, 2021 - Apr 3, 2023	-41.01% Sep 20, 2006 - Sep 18, 2008
#5	-43.83% Jan 4, 2018 - Mar 14, 2018	-31.67% Nov 25, 2024 - Sep 18, 2025
#6	-31.32% Sep 6, 2019 - Jan 7, 2020	-29.83% Nov 17, 1999 - Jun 29, 2001
#7	-28.91% Jan 8, 2021 - Jun 1, 2021	-29.30% Nov 25, 2015 - Nov 10, 2016
#8	-21.52% Mar 16, 2018 - Apr 11, 2018	-27.52% Mar 12, 2021 - Jan 6, 2022
#9	-12.47% Dec 11, 2017 - Dec 21, 2017	-21.92% Jun 17, 2002 - May 16, 2003
#10	-8.62% May 5, 2023 - Jun 13, 2023	-19.31% Dec 1, 2004 - Jul 8, 2005
#11	-8.38% Dec 8, 2020 - Dec 15, 2020	-18.94% Jul 11, 2005 - Mar 14, 2006
#12	-8.03% Jun 14, 2021 - Jul 1, 2021	-17.65% Dec 3, 2003 - Oct 1, 2004
#13	-6.75% Apr 24, 2023 - May 5, 2023	-16.88% Jun 26, 2015 - Nov 6, 2015
#14	-6.20% Jan 21, 2020 - Feb 3, 2020	-14.98% Jul 23, 2024 - Oct 16, 2024
#15	-5.53% Nov 13, 2017 - Dec 8, 2017	-14.77% Jun 29, 2001 - Dec 17, 2001