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ANRO vs SPY

Comparison between Alto Neuroscience Inc (ANRO, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

ANRO vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
ANRO
$715M
Winner
SPY
$735B
Expense Ratio
ANRO
N/A
SPY
0.09%
Max Drawdown
ANRO
91.74%
Winner
SPY
56.47%
Sharpe Ratio
Winner
ANRO
2.07
SPY
1.62
5Y Beta
ANRO
1.25
Winner
SPY
1.00
Industry
ANRO
Biotechnology
SPY
N/A
P/E Ratio
Winner
ANRO
-8.38
SPY
28.99
Forward P/E
ANRO
N/A
SPY
22.37
PEG Ratio
ANRO
-2.16
SPY
N/A
5Y Dividends CAGR
ANRO
N/A
SPY
5.43%
5Y EPS CAGR
ANRO
N/A
SPY
26.05%
Debt to Equity
Winner
ANRO
6.58%
SPY
32.40%
Free Cash Flow Yield
ANRO
-8.80%
SPY
N/A
P/S Ratio
ANRO
N/A
SPY
3.74
P/B Ratio
Winner
ANRO
2.89
SPY
5.61

ANRO vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
ANRO
-24.73%
Winner
SPY
+0.22%
3M
ANRO
-16.96%
Winner
SPY
+9.29%
6M
Winner
ANRO
+31.94%
SPY
+8.75%
1Y
Winner
ANRO
+618.90%
SPY
+24.68%
5Y(CAGR)
ANRO
N/A
SPY
+13.40%
10Y(CAGR)
ANRO
N/A
SPY
+15.16%
Max(CAGR)
ANRO
-5.21%
Winner
SPY
+8.48%

ANRO vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearANROSPY
2026+10.07%+8.50%
2025+306.39%+18.00%
2024-79.57%+25.59%
2023N/A+26.72%
2022N/A-18.64%
2021N/A+30.52%
2020N/A+17.28%
2019N/A+31.09%
2018N/A-5.24%
2017N/A+20.78%
2016N/A+13.59%
2015N/A+1.31%
2014N/A+14.56%
2013N/A+29.00%
2012N/A+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

ANRO vs SPY Drawdown Comparison

The maximum drawdown for ANRO was -91.74%, occurring on Apr 4, 2025. Recovery took 523 trading sessions.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current ANRO drawdown is -34.13%. The current SPY drawdown is -2.68%.

RankANROSPY
#1-91.74%
Feb 5, 2024 - Mar 9, 2026		-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-34.13%
Apr 17, 2026 - Jun 5, 2026		-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-17.74%
Mar 16, 2026 - Apr 13, 2026		-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-5.05%
Mar 9, 2026 - Mar 11, 2026		-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-3.56%
Mar 11, 2026 - Mar 16, 2026		-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-1.36%
Apr 14, 2026 - Apr 16, 2026		-18.76%
Feb 19, 2025 - Jun 26, 2025
#7N/A-13.02%
Jul 20, 2015 - Apr 18, 2016
#8N/A-10.10%
Jan 26, 2018 - Aug 6, 2018
#9N/A-9.44%
Sep 2, 2020 - Nov 11, 2020
#10N/A-9.30%
Jan 19, 2000 - Mar 17, 2000
#11N/A-9.05%
Jul 19, 2007 - Oct 5, 2007
#12N/A-8.88%
Jan 27, 2026 - Apr 14, 2026
#13N/A-8.41%
Jul 16, 2024 - Sep 19, 2024
#14N/A-7.35%
Sep 14, 2012 - Jan 2, 2013
#15N/A-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between ANRO and SPY is 0.41 which considered as a weak positive correlation - the stocks show a slight tendency to move together.

0.41
-101

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