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AMLX vs ZBIO

Comparison between Amylyx Pharmaceuticals Inc (AMLX, Company) and Zenas Biopharma Inc (ZBIO, Company).

Both AMLX and ZBIO are from the Healthcare sector.

AMLX vs ZBIO - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap
Winner
AMLX
$1.97B
ZBIO
$1.96B
Max Drawdown
AMLX
96.04%
Winner
ZBIO
74.96%
Sharpe Ratio
Winner
AMLX
1.50
ZBIO
1.29
5Y Beta
Winner
AMLX
1.15
ZBIO
1.25
Industry
AMLX
Drug Manufacturers - Specialty & Generic
ZBIO
Biotechnology
P/E Ratio
Winner
AMLX
-12.20
ZBIO
-3.85
Forward P/E
AMLX
2.77
ZBIO
N/A
Debt to Equity
AMLX
0.00%
ZBIO
0.00%
Free Cash Flow Yield
Winner
AMLX
-6.13%
ZBIO
-10.71%

AMLX vs ZBIO - Historical Returns

Returns include dividend reinvestment.

1M
AMLX
+7.45%
Winner
ZBIO
+53.38%
3M
AMLX
+1.56%
Winner
ZBIO
+67.60%
6M
AMLX
+11.61%
Winner
ZBIO
+54.26%
1Y
Winner
AMLX
+109.65%
ZBIO
+98.40%
5Y(CAGR)
AMLX
-0.59%
ZBIO
N/A
Max(CAGR)
AMLX
-0.59%
Winner
ZBIO
+33.40%

AMLX vs ZBIO - Annual Returns (2022 - 2026)

Returns include dividend reinvestment.

YearAMLXZBIO
2026+54.03%-10.17%
2025+208.95%+303.00%
2024-74.75%-54.88%
2023-59.09%N/A
2022+104.48%N/A

AMLX vs ZBIO Drawdown Comparison

The maximum drawdown for AMLX was -96.04%, occurring on Jun 18, 2024. This drawdown has not yet recovered.

The maximum drawdown for ZBIO was -74.96%, occurring on Jan 28, 2025. Recovery took 240 trading sessions.

The current AMLX drawdown is -57.02%. The current ZBIO drawdown is -28.21%.

RankAMLXZBIO
#1-96.04%
Jan 27, 2023 - Jun 18, 2024
-74.96%
Oct 22, 2024 - Oct 8, 2025
#2-79.18%
Feb 28, 2022 - Oct 10, 2022
-64.79%
Dec 24, 2025 - Jan 6, 2026
#3-17.59%
Feb 1, 2022 - Feb 18, 2022
-19.71%
Dec 12, 2025 - Dec 22, 2025
#4-15.23%
Dec 1, 2022 - Jan 24, 2023
-14.88%
Nov 26, 2025 - Dec 12, 2025
#5-13.39%
Oct 26, 2022 - Nov 25, 2022
-13.92%
Oct 9, 2025 - Oct 27, 2025
#6-12.97%
Jan 19, 2022 - Jan 31, 2022
-12.01%
Sep 24, 2024 - Oct 15, 2024
#7-7.90%
Jan 13, 2022 - Jan 19, 2022
-11.92%
Oct 27, 2025 - Nov 6, 2025
#8-7.47%
Jan 7, 2022 - Jan 11, 2022
-6.22%
Nov 19, 2025 - Nov 24, 2025
#9-5.42%
Nov 25, 2022 - Dec 1, 2022
-3.47%
Sep 13, 2024 - Sep 20, 2024
#10-3.44%
Feb 22, 2022 - Feb 24, 2022
-3.39%
Nov 7, 2025 - Nov 11, 2025
#11-3.19%
Oct 10, 2022 - Oct 13, 2022
-2.23%
Nov 12, 2025 - Nov 17, 2025
#12-2.79%
Oct 13, 2022 - Oct 17, 2022
-2.16%
Sep 20, 2024 - Sep 24, 2024
#13-1.41%
Oct 18, 2022 - Oct 21, 2022
-1.27%
Oct 15, 2024 - Oct 17, 2024
#14-1.06%
Jan 25, 2023 - Jan 27, 2023
-0.56%
Oct 17, 2024 - Oct 21, 2024

Correlation

Correlation between AMLX and ZBIO is 0.76 which considered as a strong positive correlation - the stocks tend to move together.

0.76
-101

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