ALNY vs ONC

Comparison between Alnylam Pharmaceuticals Inc (ALNY, Company) and BeiGene Ltd (ONC, Company).

Both ALNY and ONC are from the Healthcare sector.

5-Year PerformanceALNY has outperformed ONC, delivering a return of +4.3% compared to -1.7%

ALNY vs ONC - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ALNY(COMPANY)	ONC(COMPANY)
Market Cap	$38B	$38B
Max Drawdown	83.58%	69.96%
Sharpe Ratio	-1.11	0.21
5Y Beta	0.79	0.54
Industry	Biotechnology	Biotechnology
P/E Ratio	121.13	73.10
Forward P/E	23.42	47.85
PEG Ratio	0.51	N/A
Debt to Equity	0.00%	24.13%
Free Cash Flow Yield	1.23%	2.23%
P/S Ratio	8.93	5.82
P/B Ratio	35.81	7.13

Market Cap

Winner

ALNY

$38B

ONC

$38B

Max Drawdown

ALNY

83.58%

Winner

ONC

69.96%

Sharpe Ratio

ALNY

-1.11

Winner

ONC

0.21

5Y Beta

ALNY

0.79

Winner

ONC

0.54

Industry

ALNY

Biotechnology

ONC

Biotechnology

P/E Ratio

ALNY

121.13

Winner

ONC

73.10

Forward P/E

Winner

ALNY

23.42

ONC

47.85

PEG Ratio

ALNY

0.51

ONC

N/A

Debt to Equity

Winner

ALNY

0.00%

ONC

24.13%

Free Cash Flow Yield

ALNY

1.23%

Winner

ONC

2.23%

P/S Ratio

ALNY

8.93

Winner

ONC

5.82

P/B Ratio

ALNY

35.81

Winner

ONC

7.13

ALNY vs ONC - Historical Returns

Returns include dividend reinvestment.

Period	ALNY	ONC
1 month	-29.56%	+5.42%
3 months	-26.05%	+5.60%
6 months	-37.37%	-9.41%
1 year	-47.48%	+3.11%
5 years(CAGR)	+4.27%	-1.68%
10 years(CAGR)	+11.94%	+28.00%
Max(CAGR)	+16.83%	+25.75%

ALNY

-29.56%

Winner

ONC

+5.42%

ALNY

-26.05%

Winner

ONC

+5.60%

ALNY

-37.37%

Winner

ONC

-9.41%

ALNY

-47.48%

Winner

ONC

+3.11%

5Y(CAGR)

Winner

ALNY

+4.27%

ONC

-1.68%

10Y(CAGR)

ALNY

+11.94%

Winner

ONC

+28.00%

Max(CAGR)

ALNY

+16.83%

Winner

ONC

+25.75%

ALNY vs ONC - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	ALNY	ONC
2026	-44.94%	+0.88%
2025	+70.21%	+65.11%
2024	+20.72%	+4.36%
2023	-18.06%	-20.42%
2022	+36.65%	-18.41%
2021	+32.38%	+3.80%
2020	+12.41%	+55.73%
2019	+58.29%	+21.86%
2018	-44.70%	+39.13%
2017	+228.80%	+214.72%
2016	-59.75%	+7.20%
2015	-3.71%	N/A
2014	+51.89%	N/A
2013	+235.42%	N/A
2012	+110.74%	N/A
2011	-18.58%	N/A
2010	-45.64%	N/A
2009	-29.94%	N/A
2008	-14.49%	N/A
2007	+34.82%	N/A
2006	+65.12%	N/A
2005	+76.25%	N/A
2004	+6.71%	N/A

ALNY vs ONC Drawdown Comparison

The maximum drawdown for ALNY was -83.58%, occurring on Oct 3, 2011. Recovery took 1443 trading sessions.

The maximum drawdown for ONC was -69.96%, occurring on May 11, 2022. This drawdown has not yet recovered.

The current ALNY drawdown is -55.15%. The current ONC drawdown is -22.17%.

Rank	ALNY	ONC
#1	-83.58% Oct 9, 2007 - Jul 3, 2013	-69.96% Sep 17, 2021 - May 11, 2022
#2	-77.36% Jun 22, 2015 - Nov 10, 2017	-50.63% Jun 8, 2018 - Jul 14, 2020
#3	-58.17% Oct 20, 2025 - Jul 30, 2026	-34.68% Feb 16, 2021 - Sep 16, 2021
#4	-57.81% Mar 20, 2018 - Jun 19, 2020	-30.62% Oct 10, 2017 - Jan 18, 2018
#5	-52.18% Jun 9, 2004 - Jan 6, 2005	-30.10% Oct 16, 2020 - Jan 14, 2021
#6	-47.61% Jan 13, 2014 - Oct 24, 2014	-29.28% Feb 5, 2016 - Nov 10, 2016
#7	-42.46% Oct 14, 2021 - Aug 3, 2022	-26.96% Nov 16, 2016 - Feb 14, 2017
#8	-40.61% Dec 21, 2022 - Jun 26, 2024	-18.35% Jul 20, 2020 - Sep 15, 2020
#9	-36.52% Mar 29, 2006 - Oct 31, 2006	-15.57% Aug 8, 2017 - Sep 15, 2017
#10	-36.33% Dec 8, 2006 - Jul 11, 2007	-15.53% Jan 25, 2021 - Feb 10, 2021
#11	-34.67% Sep 12, 2005 - Jan 10, 2006	-12.11% Feb 1, 2018 - Feb 21, 2018
#12	-32.55% Jan 10, 2005 - Sep 7, 2005	-11.21% Feb 16, 2017 - Apr 28, 2017
#13	-26.79% Jan 25, 2021 - Jun 18, 2021	-10.84% Mar 21, 2018 - May 2, 2018
#14	-26.77% Jul 20, 2020 - Jan 12, 2021	-10.74% Apr 28, 2017 - Jun 2, 2017
#15	-25.36% Oct 16, 2024 - May 30, 2025	-10.36% Nov 10, 2016 - Nov 15, 2016