ZYME vs NKTR

Comparison between Zymeworks BC Inc (ZYME, Company) and Nektar Therapeutics (NKTR, Company).

Both ZYME and NKTR are from the Healthcare sector.

5-Year PerformanceZYME has outperformed NKTR, delivering a return of -8.2% compared to -22.5%

ZYME vs NKTR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ZYME(COMPANY)	NKTR(COMPANY)
Market Cap	$1.71B	$1.71B
Max Drawdown	91.81%	99.61%
Sharpe Ratio	1.08	1.52
5Y Beta	0.84	1.81
Industry	Biotechnology	Biotechnology
P/E Ratio	-16.85	-7.65
Forward P/E	24.04	34.01
PEG Ratio	0.00	0.31
5Y EPS CAGR	N/A	-24.01%
Debt to Equity	0.00%	24.89%
Free Cash Flow Yield	-4.51%	-11.89%
P/S Ratio	21.15	42.10
P/B Ratio	10.82	4.03

Market Cap

ZYME

$1.71B

Winner

NKTR

$1.71B

Max Drawdown

Winner

ZYME

91.81%

NKTR

99.61%

Sharpe Ratio

ZYME

1.08

Winner

NKTR

1.52

5Y Beta

Winner

ZYME

0.84

NKTR

1.81

Industry

ZYME

Biotechnology

NKTR

Biotechnology

P/E Ratio

Winner

ZYME

-16.85

NKTR

-7.65

Forward P/E

Winner

ZYME

24.04

NKTR

34.01

PEG Ratio

Winner

ZYME

0.00

NKTR

0.31

5Y EPS CAGR

ZYME

N/A

NKTR

-24.01%

Debt to Equity

Winner

ZYME

0.00%

NKTR

24.89%

Free Cash Flow Yield

Winner

ZYME

-4.51%

NKTR

-11.89%

P/S Ratio

Winner

ZYME

21.15

NKTR

42.10

P/B Ratio

ZYME

10.82

Winner

NKTR

4.03

ZYME vs NKTR - Historical Returns

Returns include dividend reinvestment.

Period	ZYME	NKTR
1 month	-3.18%	+4.00%
3 months	-15.71%	-24.00%
6 months	-0.52%	+86.90%
1 year	+61.79%	+177.44%
5 years(CAGR)	-8.19%	-22.48%
10 years(CAGR)	+6.43%	-11.22%
Max(CAGR)	+6.43%	-3.91%

ZYME

-3.18%

Winner

NKTR

+4.00%

Winner

ZYME

-15.71%

NKTR

-24.00%

ZYME

-0.52%

Winner

NKTR

+86.90%

ZYME

+61.79%

Winner

NKTR

+177.44%

5Y(CAGR)

Winner

ZYME

-8.19%

NKTR

-22.48%

10Y(CAGR)

Winner

ZYME

+6.43%

NKTR

-11.22%

Max(CAGR)

Winner

ZYME

+6.43%

NKTR

-3.91%

ZYME vs NKTR - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	ZYME	NKTR
2026	-13.15%	+59.74%
2025	+78.15%	+193.31%
2024	+41.04%	+56.36%
2023	+37.80%	-74.20%
2022	-53.71%	-83.46%
2021	-66.53%	-23.50%
2020	-0.69%	-18.89%
2019	+209.46%	-36.91%
2018	+85.05%	-42.98%
2017	-41.59%	+370.61%
2016	N/A	-24.26%
2015	N/A	+11.11%
2014	N/A	+30.58%
2013	N/A	+50.53%
2012	N/A	+28.65%
2011	N/A	-55.35%
2010	N/A	+32.75%
2009	N/A	+60.97%
2008	N/A	-15.76%
2007	N/A	-55.97%
2006	N/A	-7.48%
2005	N/A	-16.70%
2004	N/A	+41.54%
2003	N/A	+59.00%
2002	N/A	-55.65%
2001	N/A	-58.31%
2000	N/A	+142.26%
1999	N/A	+58.33%

ZYME vs NKTR Drawdown Comparison

The maximum drawdown for ZYME was -91.81%, occurring on Sep 7, 2022. This drawdown has not yet recovered.

The maximum drawdown for NKTR was -99.61%, occurring on Nov 28, 2023. This drawdown has not yet recovered.

The current ZYME drawdown is -59.30%. The current NKTR drawdown is -95.74%.

Rank	ZYME	NKTR
#1	-91.81% Jan 8, 2021 - Sep 7, 2022	-99.61% Mar 8, 2018 - Nov 28, 2023
#2	-51.24% Jan 22, 2020 - Nov 27, 2020	-95.53% Mar 7, 2000 - Jan 9, 2018
#3	-51.20% May 3, 2017 - Feb 1, 2018	-22.54% Jan 24, 2000 - Feb 8, 2000
#4	-49.91% Jun 1, 2018 - Jun 24, 2019	-15.89% Feb 1, 2018 - Feb 23, 2018
#5	-28.19% Feb 1, 2018 - Apr 26, 2018	-10.44% Nov 15, 1999 - Dec 15, 1999
#6	-14.72% Sep 6, 2019 - Oct 17, 2019	-9.53% Feb 17, 2000 - Mar 2, 2000
#7	-14.38% Dec 4, 2020 - Jan 8, 2021	-6.64% Feb 26, 2018 - Mar 2, 2018
#8	-10.39% Apr 27, 2018 - May 15, 2018	-5.12% Nov 8, 1999 - Nov 15, 1999
#9	-10.05% Dec 4, 2019 - Dec 18, 2019	-4.78% Dec 16, 1999 - Dec 20, 1999
#10	-8.78% Jan 2, 2020 - Jan 17, 2020	-4.65% Mar 2, 2018 - Mar 8, 2018
#11	-8.26% Nov 5, 2019 - Nov 18, 2019	-4.58% Dec 27, 1999 - Jan 4, 2000
#12	-7.96% Jul 9, 2019 - Aug 15, 2019	-4.55% Feb 9, 2000 - Feb 16, 2000
#13	-6.40% Aug 16, 2019 - Aug 28, 2019	-3.61% Jan 12, 2018 - Jan 22, 2018
#14	-4.63% May 30, 2018 - Jun 1, 2018	-1.62% Jan 23, 2018 - Jan 25, 2018
#15	-3.62% Nov 29, 2019 - Dec 4, 2019	-1.30% Dec 21, 1999 - Dec 23, 1999