XPH vs AIS
Comparison between STATE STREET(R) SPDR(R) S&P(R) PHARMACEUTICALS ETF (XPH, ETF) and VISTASHARES ARTIFICIAL INTELLIGENCE SUPERCYCLE ETF (AIS, ETF).
XPH vs AIS - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Net Assets
Winner
XPH
$355M
AIS
$354M
Expense Ratio
Winner
XPH
0.35%
AIS
0.75%
Max Drawdown
XPH
52.72%
Winner
AIS
32.78%
Sharpe Ratio
XPH
1.48
Winner
AIS
2.78
5Y Beta
Winner
XPH
0.77
AIS
1.71
P/E Ratio
Winner
XPH
-26.31
AIS
72.32
Forward P/E
Winner
XPH
10.86
AIS
30.72
PEG Ratio
XPH
N/A
AIS
0.27
5Y Dividends CAGR
XPH
10.65%
AIS
N/A
5Y EPS CAGR
XPH
-2.08%
AIS
N/A
Debt to Equity
XPH
14.34%
AIS
N/A
P/S Ratio
Winner
XPH
2.40
AIS
3.75
P/B Ratio
Winner
XPH
3.32
AIS
13.75
XPH vs AIS - Holdings Comparison
XPH and AIS have 1 common holdings. Overlap is -0.11%
XPH's top 25 holdings weight is 55.14%. AIS's top 25 holdings weight is 79.36%.
| Rank | XPH | AIS |
|---|---|---|
| #1 | ORGANON & CO ORDINARY SHARES (OGN) - 3.81% | SK HYNIX INC (n/a) - 11.00% |
| #2 | CORCEPT THERAPEUTICS INC (CORT) - 3.25% | MICRON TECHNOLOGY INC (MU) - 7.91% |
| #3 | LIQUIDIA CORP ORDINARY SHARES (LQDA) - 2.84% | ADVANCED MICRO DEVICES INC (AMD) - 4.63% |
| #4 | AXSOME THERAPEUTICS INC (AXSM) - 2.67% | NAVITAS SEMICONDUCTOR CORP CLASS A (NVTS) - 4.05% |
| #5 | ENLIVEN THERAPEUTICS INC (ELVN) - 2.52% | SILICON MOTION TECHNOLOGY CORP ADR (SIMO) - 4.01% |
| #6 | JAZZ PHARMACEUTICALS PLC (JAZZ) - 2.33% | VERTIV HOLDINGS CO CLASS A (VRT) - 3.91% |
| #7 | DEFINIUM THERAPEUTICS INC ORDINARY SHARES (DFTX) - 2.23% | VICOR CORP (VICR) - 3.61% |
| #8 | TREVI THERAPEUTICS INC (TRVI) - 2.19% | INTEL CORP (INTC) - 3.45% |
| #9 | VIATRIS INC (VTRS) - 2.12% | MARVELL TECHNOLOGY INC (MRVL) - 3.37% |
| #10 | ESPERION THERAPEUTICS INC (ESPR) - 2.11% | n/a (TSM) - 3.14% |
| #11 | INDIVIOR PHARMACEUTICALS INC ORDINARY SHARE (INDV) - 2.10% | GE VERNOVA INC (GEV) - 2.96% |
| #12 | ROYALTY PHARMA PLC CLASS A (RPRX) - 2.10% | n/a (n/a) - 2.75% |
| #13 | PERRIGO CO PLC (PRGO) - 2.00% | SEAGATE TECHNOLOGY HOLDINGS PLC (STX) - 2.61% |
| #14 | EDGEWISE THERAPEUTICS INC (EWTX) - 1.97% | NVIDIA CORP (NVDA) - 2.59% |
| #15 | MBX BIOSCIENCES INC (MBX) - 1.96% | SAMSUNG ELECTRONICS CO LTD (n/a) - 2.15% |
| #16 | ANI PHARMACEUTICALS INC (ANIP) - 1.94% | CORNING INC (GLW) - 2.13% |
| #17 | ELI LILLY AND CO (LLY) - 1.94% | ARM HOLDINGS PLC ADR (ARM) - 1.97% |
| #18 | PACIRA BIOSCIENCES INC (PCRX) - 1.94% | LEGRAND SA (n/a) - 1.82% |
| #19 | LIGAND PHARMACEUTICALS INC (LGND) - 1.94% | SANDISK CORP ORDINARY SHARES (SNDK) - 1.80% |
| #20 | HARMONY BIOSCIENCES HOLDINGS INC ORDINARY SHARES (HRMY) - 1.90% | UNIMICRON TECHNOLOGY CORP (n/a) - 1.70% |
| #21 | XERIS BIOPHARMA HOLDINGS INC (XERS) - 1.88% | ASTERA LABS INC (ALAB) - 1.70% |
| #22 | MERCK & CO INC (MRK) - 1.87% | ASML HOLDING NV ADR (ASML) - 1.66% |
| #23 | NUVATION BIO INC ORDINARY SHARES CLASS A (NUVB) - 1.86% | WESTERN DIGITAL CORP (WDC) - 1.51% |
| #24 | INNOVIVA INC (INVA) - 1.84% | MPI CORP (n/a) - 1.47% |
| #25 | AMNEAL PHARMACEUTICALS INC ORDINARY SHARES CLASS A (AMRX) - 1.83% | MONTAGE TECHNOLOGY CO LTD CLASS A (n/a) - 1.46% |
| Total Holdings | 59 | 62 |
XPH vs AIS - Historical Returns
Returns include dividend reinvestment.
1M
XPH
-4.57%
Winner
AIS
+11.14%
3M
XPH
+3.27%
Winner
AIS
+64.26%
6M
XPH
+5.26%
Winner
AIS
+88.58%
1Y
XPH
+39.58%
Winner
AIS
+176.20%
5Y(CAGR)
XPH
+3.76%
AIS
N/A
10Y(CAGR)
XPH
+3.42%
AIS
N/A
Max(CAGR)
XPH
+8.49%
Winner
AIS
+99.48%
XPH vs AIS - Annual Returns (2006 - 2026)
Returns include dividend reinvestment.
| Year | XPH | AIS |
|---|---|---|
| 2026 | +3.43% | +79.54% |
| 2025 | +32.67% | +57.93% |
| 2024 | +4.80% | -4.92% |
| 2023 | +3.85% | N/A |
| 2022 | -10.72% | N/A |
| 2021 | -9.89% | N/A |
| 2020 | +14.99% | N/A |
| 2019 | +24.63% | N/A |
| 2018 | -16.41% | N/A |
| 2017 | +9.20% | N/A |
| 2016 | -21.50% | N/A |
| 2015 | +1.71% | N/A |
| 2014 | +30.23% | N/A |
| 2013 | +58.86% | N/A |
| 2012 | +10.07% | N/A |
| 2011 | +11.81% | N/A |
| 2010 | +19.70% | N/A |
| 2009 | +25.21% | N/A |
| 2008 | -8.06% | N/A |
| 2007 | -1.40% | N/A |
| 2006 | +11.12% | N/A |
XPH vs AIS Drawdown Comparison
The maximum drawdown for XPH was -48.04%, occurring on Mar 23, 2020. Recovery took 2621 trading sessions.
The maximum drawdown for AIS was -32.78%, occurring on Apr 8, 2025. Recovery took 100 trading sessions.
The current XPH drawdown is -6.03%. The current AIS drawdown is -14.22%.
| Rank | XPH | AIS |
|---|---|---|
| #1 | -48.04% Jul 22, 2015 - Dec 22, 2025 | -32.78% Jan 22, 2025 - Jun 16, 2025 |
| #2 | -35.26% May 9, 2007 - Oct 14, 2009 | -15.84% Oct 29, 2025 - Jan 15, 2026 |
| #3 | -17.59% Jul 7, 2011 - Jan 9, 2012 | -15.76% Feb 25, 2026 - Apr 8, 2026 |
| #4 | -14.50% Mar 5, 2014 - Jun 20, 2014 | -14.22% Jun 3, 2026 - Jun 5, 2026 |
| #5 | -13.17% Sep 18, 2012 - Feb 19, 2013 | -8.19% May 14, 2026 - May 22, 2026 |
| #6 | -11.97% Feb 25, 2026 - Apr 17, 2026 | -7.55% Jan 28, 2026 - Feb 9, 2026 |
| #7 | -10.95% Apr 5, 2010 - Sep 13, 2010 | -6.93% Dec 5, 2024 - Jan 21, 2025 |
| #8 | -10.85% Jul 3, 2014 - Sep 17, 2014 | -5.60% Oct 8, 2025 - Oct 16, 2025 |
| #9 | -10.60% Mar 19, 2015 - Jul 14, 2015 | -4.99% Aug 13, 2025 - Aug 28, 2025 |
| #10 | -9.08% Oct 15, 2009 - Nov 23, 2009 | -4.22% May 11, 2026 - May 13, 2026 |
| #11 | -8.24% May 6, 2026 - Jun 2, 2026 | -3.88% Apr 27, 2026 - Apr 30, 2026 |
| #12 | -7.03% Sep 24, 2014 - Oct 28, 2014 | -3.67% May 6, 2026 - May 8, 2026 |
| #13 | -6.73% Feb 20, 2007 - Apr 12, 2007 | -3.32% Aug 28, 2025 - Sep 8, 2025 |
| #14 | -6.56% Jan 18, 2011 - Apr 4, 2011 | -2.66% Jul 30, 2025 - Aug 12, 2025 |
| #15 | -6.43% Apr 27, 2012 - Jun 19, 2012 | -2.50% Sep 22, 2025 - Oct 1, 2025 |
Correlation
Correlation between XPH and AIS is 0.83 which considered as a strong positive correlation - the stocks tend to move together.
0.83
-101
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