XLO vs INCR

Comparison between Xilio Therapeutics Inc (XLO, Company) and INC Research Holdings Inc (INCR, Company).

Both XLO and INCR are from the Healthcare sector.

5-Year PerformanceINCR has outperformed XLO, delivering a return of -31.6% compared to -49.9%

XLO vs INCR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	XLO(COMPANY)	INCR(COMPANY)
Market Cap	$51M	$51M
Max Drawdown	98.01%	98.80%
Sharpe Ratio	-0.02	-0.35
5Y Beta	0.77	0.62
Industry	Biotechnology	Drug Manufacturers - Specialty & Generic
P/E Ratio	-1.09	-4.69
Forward P/E	N/A	6.18
Debt to Equity	0.00%	46.15%
Free Cash Flow Yield	N/A	8.24%
P/S Ratio	1.08	0.53
P/B Ratio	0.80	0.39

Market Cap

Winner

XLO

$51M

INCR

$51M

Max Drawdown

Winner

XLO

98.01%

INCR

98.80%

Sharpe Ratio

Winner

XLO

-0.02

INCR

-0.35

5Y Beta

XLO

0.77

Winner

INCR

0.62

Industry

XLO

Biotechnology

INCR

Drug Manufacturers - Specialty & Generic

P/E Ratio

XLO

-1.09

Winner

INCR

-4.69

Forward P/E

XLO

N/A

INCR

6.18

Debt to Equity

Winner

XLO

0.00%

INCR

46.15%

Free Cash Flow Yield

XLO

N/A

INCR

8.24%

P/S Ratio

XLO

1.08

Winner

INCR

0.53

P/B Ratio

XLO

0.80

Winner

INCR

0.39

XLO vs INCR - Historical Returns

Returns include dividend reinvestment.

Period	XLO	INCR
1 month	+7.88%	+24.17%
3 months	+13.23%	+41.56%
6 months	-4.00%	-7.63%
1 year	-5.12%	-29.68%
5 years(CAGR)	-49.89%	-31.56%
10 years(CAGR)	N/A	-30.15%
Max(CAGR)	-49.89%	-22.30%

XLO

+7.88%

Winner

INCR

+24.17%

XLO

+13.23%

Winner

INCR

+41.56%

Winner

XLO

-4.00%

INCR

-7.63%

Winner

XLO

-5.12%

INCR

-29.68%

5Y(CAGR)

XLO

-49.89%

Winner

INCR

-31.56%

10Y(CAGR)

XLO

N/A

INCR

-30.15%

Max(CAGR)

XLO

-49.89%

Winner

INCR

-22.30%

XLO vs INCR - Annual Returns (2014 - 2026)

Returns include dividend reinvestment.

Year	XLO	INCR
2026	-5.36%	+5.83%
2025	-40.17%	-42.41%
2024	+66.09%	+21.94%
2023	-79.55%	-63.67%
2022	-83.24%	-52.92%
2021	+0.00%	-4.00%
2018	N/A	-8.16%
2017	N/A	-15.91%
2016	N/A	+12.85%
2015	N/A	+94.58%
2014	N/A	+25.38%

XLO vs INCR Drawdown Comparison

The maximum drawdown for XLO was -98.01%, occurring on Dec 20, 2023. This drawdown has not yet recovered.

The maximum drawdown for INCR was -98.80%, occurring on Mar 25, 2026. This drawdown has not yet recovered.

The current XLO drawdown is -97.47%. The current INCR drawdown is -98.20%.

Rank	XLO	INCR
#1	-98.01% Nov 16, 2021 - Dec 20, 2023	-98.80% Jun 19, 2017 - Mar 25, 2026
#2	-15.07% Nov 2, 2021 - Nov 4, 2021	-29.33% Aug 5, 2015 - Apr 25, 2016
#3	-7.66% Nov 4, 2021 - Nov 8, 2021	-27.67% Feb 27, 2017 - May 16, 2017
#4	-6.89% Nov 8, 2021 - Nov 16, 2021	-26.64% Apr 25, 2016 - Nov 11, 2016
#5	-2.19% Oct 26, 2021 - Oct 29, 2021	-17.98% Jan 12, 2015 - Feb 24, 2015
#6	N/A	-17.82% Apr 28, 2015 - Jun 3, 2015
#7	N/A	-10.40% Mar 19, 2015 - Apr 27, 2015
#8	N/A	-9.58% Jun 23, 2015 - Jul 14, 2015
#9	N/A	-8.88% Dec 3, 2014 - Dec 22, 2014
#10	N/A	-7.64% Jul 20, 2015 - Jul 30, 2015
#11	N/A	-6.47% Dec 29, 2014 - Jan 8, 2015
#12	N/A	-5.83% Jan 10, 2017 - Feb 1, 2017
#13	N/A	-5.35% Nov 25, 2016 - Dec 15, 2016
#14	N/A	-4.53% Feb 25, 2015 - Mar 12, 2015
#15	N/A	-4.46% Jun 8, 2017 - Jun 19, 2017