XERS vs JBIO

Comparison between Xeris Biopharma Holdings Inc (XERS, Company) and Jade Biosciences Inc (JBIO, Company).

Both XERS and JBIO are from the Healthcare sector.

5-Year PerformanceXERS has outperformed JBIO, delivering a return of +29.1% compared to -41.7%

XERS vs JBIO - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	XERS(COMPANY)	JBIO(COMPANY)
Market Cap	$1.47B	$1.48B
Max Drawdown	96.22%	99.37%
Sharpe Ratio	0.51	1.88
5Y Beta	0.93	0.56
Industry	Drug Manufacturers - Specialty & Generic	Biotechnology
P/E Ratio	-88.62	-7.45
Forward P/E	99.01	N/A
PEG Ratio	N/A	-4.16
Debt to Equity	-2594.93%	0.00%
Free Cash Flow Yield	3.84%	-8.38%
P/B Ratio	N/A	4.46

Market Cap

XERS

$1.47B

Winner

JBIO

$1.48B

Max Drawdown

Winner

XERS

96.22%

JBIO

99.37%

Sharpe Ratio

XERS

0.51

Winner

JBIO

1.88

5Y Beta

XERS

0.93

Winner

JBIO

0.56

Industry

XERS

Drug Manufacturers - Specialty & Generic

JBIO

Biotechnology

P/E Ratio

Winner

XERS

-88.62

JBIO

-7.45

Forward P/E

XERS

99.01

JBIO

N/A

PEG Ratio

XERS

N/A

JBIO

-4.16

Debt to Equity

Winner

XERS

-2594.93%

JBIO

0.00%

Free Cash Flow Yield

Winner

XERS

3.84%

JBIO

-8.38%

P/B Ratio

XERS

N/A

JBIO

4.46

XERS vs JBIO - Historical Returns

Returns include dividend reinvestment.

Period	XERS	JBIO
1 month	+2.08%	+11.78%
3 months	+29.55%	-5.03%
6 months	+22.14%	+58.42%
1 year	+14.42%	+224.83%
5 years(CAGR)	+29.14%	-41.71%
10 years(CAGR)	-10.32%	N/A
Max(CAGR)	-10.32%	-47.52%

XERS

+2.08%

Winner

JBIO

+11.78%

Winner

XERS

+29.55%

JBIO

-5.03%

XERS

+22.14%

Winner

JBIO

+58.42%

XERS

+14.42%

Winner

JBIO

+224.83%

5Y(CAGR)

Winner

XERS

+29.14%

JBIO

-41.71%

10Y(CAGR)

XERS

-10.32%

JBIO

N/A

Max(CAGR)

Winner

XERS

-10.32%

JBIO

-47.52%

XERS vs JBIO - Annual Returns (2018 - 2026)

Returns include dividend reinvestment.

Year	XERS	JBIO
2026	+13.33%	+68.15%
2025	+126.88%	-79.69%
2024	+49.67%	-87.85%
2023	+109.82%	-16.28%
2022	-52.67%	+168.07%
2021	-44.82%	-48.36%
2020	-26.57%	N/A
2019	-59.71%	N/A
2018	-15.92%	N/A

XERS vs JBIO Drawdown Comparison

The maximum drawdown for XERS was -96.22%, occurring on Jan 5, 2023. This drawdown has not yet recovered.

The maximum drawdown for JBIO was -99.22%, occurring on Jun 13, 2025. This drawdown has not yet recovered.

The current XERS drawdown is -69.41%. The current JBIO drawdown is -97.26%.

Rank	XERS	JBIO
#1	-96.22% Sep 10, 2018 - Jan 5, 2023	-99.22% Apr 1, 2024 - Jun 13, 2025
#2	-17.12% Jul 24, 2018 - Aug 14, 2018	-68.61% Dec 12, 2022 - Apr 1, 2024
#3	-10.98% Jun 21, 2018 - Jul 20, 2018	-63.86% Jun 30, 2021 - Aug 1, 2022
#4	-7.87% Aug 14, 2018 - Aug 22, 2018	-42.73% Aug 12, 2022 - Dec 12, 2022
#5	-3.41% Aug 23, 2018 - Sep 7, 2018	-4.56% Aug 5, 2022 - Aug 12, 2022
#6	-3.07% Jul 20, 2018 - Jul 24, 2018	N/A