WDNA vs CBOL

Comparison between WISDOMTREE BIOREVOLUTION FUND (WDNA, ETF) and Calamos Laddered Bitcoin Structured Alt Protection ETF (CBOL, ETF).

WDNA vs CBOL - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	WDNA(ETF)	CBOL(ETF)
Net Assets	$2.40M	$2.40M
Expense Ratio	0.45%	0.79%
Max Drawdown	59.69%	6.72%
Sharpe Ratio	1.30	-2.75
5Y Beta	0.98	0.13
P/E Ratio	-17.09	N/A
Forward P/E	15.46	N/A
5Y EPS CAGR	11.59%	N/A
Debt to Equity	61.95%	N/A
P/S Ratio	3.65	N/A
P/B Ratio	3.45	N/A

Net Assets

WDNA

$2.40M

CBOL

$2.40M

Expense Ratio

Winner

WDNA

0.45%

CBOL

0.79%

Max Drawdown

WDNA

59.69%

Winner

CBOL

6.72%

Sharpe Ratio

Winner

WDNA

1.30

CBOL

-2.75

5Y Beta

WDNA

0.98

Winner

CBOL

0.13

P/E Ratio

WDNA

-17.09

CBOL

N/A

Forward P/E

WDNA

15.46

CBOL

N/A

5Y EPS CAGR

WDNA

11.59%

CBOL

N/A

Debt to Equity

WDNA

61.95%

CBOL

N/A

P/S Ratio

WDNA

3.65

CBOL

N/A

P/B Ratio

WDNA

3.45

CBOL

N/A

WDNA vs CBOL - Holdings Comparison

WDNA and CBOL have 0 common holdings. Overlap is 0.00%

WDNA's top 25 holdings weight is 56.92%. CBOL's top 25 holdings weight is 99.79%.

Rank	WDNA	CBOL
#1	TWIST BIOSCIENCE CORP (TWST) - 4.74%	CALAMOS BITCOIN STR ALT PRT ETF-OCT (CBOO) - 26.03%
#2	ELI LILLY AND CO (LLY) - 4.22%	CALAMOS BITCOIN STR ALT PRT ETF-JULY (CBOY) - 25.44%
#3	MODERNA INC (MRNA) - 3.15%	CALAMOS BITCOIN STR ALT PRT ETF-APR (CBOA) - 24.17%
#4	JOHNSON & JOHNSON (JNJ) - 3.04%	CALAMOS BITCOIN STR ALT PRT ETF-JAN (CBOJ) - 24.15%
#5	UNITED THERAPEUTICS CORP (UTHR) - 2.85%	N/A
#6	DARLING INGREDIENTS INC (DAR) - 2.50%	N/A
#7	IMMUNOME INC ORDINARY SHARES (IMNM) - 2.40%	N/A
#8	TEMPUS AI INC CLASS A COMMON STOCK (TEM) - 2.28%	N/A
#9	STOKE THERAPEUTICS INC (STOK) - 2.14%	N/A
#10	NATERA INC (NTRA) - 2.13%	N/A
#11	BUNGE GLOBAL SA (BG) - 2.13%	N/A
#12	CORTEVA INC (CTVA) - 2.13%	N/A
#13	BEAM THERAPEUTICS INC (BEAM) - 2.06%	N/A
#14	ASTRAZENECA PLC (n/a) - 2.00%	N/A
#15	IONIS PHARMACEUTICALS INC (IONS) - 2.00%	N/A
#16	CRISPR THERAPEUTICS AG (CRSP) - 1.97%	N/A
#17	KRYSTAL BIOTECH INC (KRYS) - 1.80%	N/A
#18	GILEAD SCIENCES INC (GILD) - 1.78%	N/A
#19	STRUCTURE THERAPEUTICS INC ADR (GPCR) - 1.71%	N/A
#20	THERMO FISHER SCIENTIFIC INC (TMO) - 1.70%	N/A
#21	n/a (TXG) - 1.69%	N/A
#22	PFIZER INC (PFE) - 1.67%	N/A
#23	AMGEN INC (AMGN) - 1.63%	N/A
#24	ROIVANT SCIENCES LTD ORDINARY SHARES (ROIV) - 1.61%	N/A
#25	REVOLUTION MEDICINES INC ORDINARY SHARES (RVMD) - 1.59%	N/A
Total Holdings	80	4

WDNA vs CBOL - Historical Returns

Returns include dividend reinvestment.

Period	WDNA	CBOL
1 month	+6.00%	-0.66%
3 months	+6.22%	-0.47%
6 months	+8.45%	-1.79%
1 year	+45.26%	N/A
5 years(CAGR)	-5.68%	N/A
Max(CAGR)	-4.78%	-6.44%

Winner

WDNA

+6.00%

CBOL

-0.66%

Winner

WDNA

+6.22%

CBOL

-0.47%

Winner

WDNA

+8.45%

CBOL

-1.79%

WDNA

+45.26%

CBOL

N/A

5Y(CAGR)

WDNA

-5.68%

CBOL

N/A

Max(CAGR)

Winner

WDNA

-4.78%

CBOL

-6.44%

WDNA vs CBOL - Annual Returns (2021 - 2026)

Returns include dividend reinvestment.

Year	WDNA	CBOL
2026	+8.23%	-2.15%
2025	+21.84%	-2.47%
2024	-14.44%	N/A
2023	-1.35%	N/A
2022	-26.69%	N/A
2021	-5.27%	N/A

WDNA vs CBOL Drawdown Comparison

The maximum drawdown for WDNA was -58.87%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for CBOL was -5.05%, occurring on Jun 5, 2026. This drawdown has not yet recovered.

The current WDNA drawdown is -30.13%. The current CBOL drawdown is -4.54%.

Rank	WDNA	CBOL
#1	-58.87% Sep 2, 2021 - Apr 8, 2025	-5.05% Oct 27, 2025 - Jun 5, 2026
#2	-6.65% Jul 1, 2021 - Aug 5, 2021	-0.82% Oct 14, 2025 - Oct 27, 2025
#3	-5.55% Aug 5, 2021 - Aug 27, 2021	N/A
#4	-2.57% Jun 14, 2021 - Jun 28, 2021	N/A
#5	-0.34% Jun 28, 2021 - Jul 1, 2021	N/A
#6	-0.24% Jun 10, 2021 - Jun 14, 2021	N/A