VTGN vs TXMD

Comparison between VistaGen Therapeutics Inc (VTGN, Company) and TherapeuticsMD Inc (TXMD, Company).

Both VTGN and TXMD are from the Healthcare sector.

5-Year PerformanceTXMD has outperformed VTGN, delivering a return of -48.1% compared to -61.9%

VTGN vs TXMD - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	VTGN(COMPANY)	TXMD(COMPANY)
Market Cap	$26M	$26M
Max Drawdown	99.76%	99.89%
Sharpe Ratio	-0.11	1.31
5Y Beta	0.97	0.63
Industry	Biotechnology	Drug Manufacturers - Specialty & Generic
P/E Ratio	-0.36	146.78
Forward P/E	N/A	2.33
PEG Ratio	-0.01	N/A
5Y EPS CAGR	-12.57%	N/A
Debt to Equity	0.00%	0.00%

Market Cap

VTGN

$26M

Winner

TXMD

$26M

Max Drawdown

Winner

VTGN

99.76%

TXMD

99.89%

Sharpe Ratio

VTGN

-0.11

Winner

TXMD

1.31

5Y Beta

VTGN

0.97

Winner

TXMD

0.63

Industry

VTGN

Biotechnology

TXMD

Drug Manufacturers - Specialty & Generic

P/E Ratio

Winner

VTGN

-0.36

TXMD

146.78

Forward P/E

VTGN

N/A

TXMD

2.33

PEG Ratio

VTGN

-0.01

TXMD

N/A

5Y EPS CAGR

VTGN

-12.57%

TXMD

N/A

Debt to Equity

VTGN

0.00%

TXMD

0.00%

VTGN vs TXMD - Historical Returns

Returns include dividend reinvestment.

Period	VTGN	TXMD
1 month	+15.87%	+12.38%
3 months	+6.75%	+1.79%
6 months	-19.86%	+35.93%
1 year	-71.01%	+102.68%
5 years(CAGR)	-61.95%	-48.14%
10 years(CAGR)	-39.49%	-40.67%
Max(CAGR)	-43.19%	-9.38%

Winner

VTGN

+15.87%

TXMD

+12.38%

Winner

VTGN

+6.75%

TXMD

+1.79%

VTGN

-19.86%

Winner

TXMD

+35.93%

VTGN

-71.01%

Winner

TXMD

+102.68%

5Y(CAGR)

VTGN

-61.95%

Winner

TXMD

-48.14%

10Y(CAGR)

Winner

VTGN

-39.49%

TXMD

-40.67%

Max(CAGR)

VTGN

-43.19%

Winner

TXMD

-9.38%

VTGN vs TXMD - Annual Returns (2003 - 2026)

Returns include dividend reinvestment.

Year	VTGN	TXMD
2026	+1.62%	+37.58%
2025	-80.03%	+3.82%
2024	-42.72%	-63.09%
2023	+31.79%	-64.00%
2022	-95.07%	-71.60%
2021	-14.85%	-71.33%
2020	+158.67%	-50.41%
2019	-56.60%	-37.63%
2018	+29.31%	-39.23%
2017	-70.26%	+1.17%
2016	-46.71%	-41.18%
2015	N/A	+136.22%
2014	N/A	-10.82%
2013	N/A	+60.31%
2012	N/A	+82.35%
2011	N/A	+4738.71%
2010	N/A	-98.00%
2009	N/A	+160.00%
2008	N/A	+48.52%
2007	N/A	-59.44%
2006	N/A	+33.33%
2005	N/A	+48.52%
2004	N/A	-8.18%
2003	N/A	-12.00%

VTGN vs TXMD Drawdown Comparison

The maximum drawdown for VTGN was -99.76%, occurring on Feb 5, 2026. This drawdown has not yet recovered.

The maximum drawdown for TXMD was -99.89%, occurring on Aug 24, 2011. Recovery took 1071 trading sessions.

The current VTGN drawdown is -99.67%. The current TXMD drawdown is -99.59%.

Rank	VTGN	TXMD
#1	-99.76% May 6, 2016 - Feb 5, 2026	-99.89% Jul 27, 2009 - Oct 25, 2013
#2	N/A	-99.87% Dec 29, 2015 - Mar 14, 2025
#3	N/A	-85.43% Mar 1, 2007 - Jul 21, 2009
#4	N/A	-80.00% Dec 11, 2003 - Jun 29, 2004
#5	N/A	-56.96% Mar 18, 2014 - Jun 5, 2015
#6	N/A	-53.02% Nov 24, 2004 - Apr 4, 2006
#7	N/A	-36.59% Jul 23, 2015 - Dec 8, 2015
#8	N/A	-31.82% Apr 4, 2006 - Dec 20, 2006
#9	N/A	-27.27% Feb 9, 2007 - Mar 1, 2007
#10	N/A	-25.10% Oct 28, 2013 - Dec 24, 2013
#11	N/A	-19.60% Jan 9, 2007 - Feb 9, 2007
#12	N/A	-11.11% Dec 20, 2006 - Jan 3, 2007
#13	N/A	-10.98% Jan 30, 2014 - Feb 27, 2014
#14	N/A	-8.69% Jun 5, 2015 - Jul 1, 2015
#15	N/A	-7.76% Dec 26, 2013 - Jan 10, 2014