UPB vs TKNO
Comparison between Upstream Bio Inc (UPB, Company) and Alpha Teknova Inc (TKNO, Company).
Both UPB and TKNO are from the Healthcare sector.
UPB vs TKNO - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
Winner
UPB
$397M
TKNO
$397M
Max Drawdown
Winner
UPB
81.84%
TKNO
95.71%
Sharpe Ratio
UPB
-0.50
Winner
TKNO
0.99
5Y Beta
Winner
UPB
1.11
TKNO
1.76
Industry
UPB
Biotechnology
TKNO
Drug Manufacturers - Specialty & Generic
P/E Ratio
UPB
-2.52
Winner
TKNO
-23.62
Debt to Equity
Winner
UPB
0.00%
TKNO
21.12%
Free Cash Flow Yield
UPB
-34.37%
Winner
TKNO
-1.85%
UPB vs TKNO - Historical Returns
Returns include dividend reinvestment.
1M
UPB
-5.08%
Winner
TKNO
+36.41%
3M
UPB
-26.18%
Winner
TKNO
+88.75%
6M
UPB
-21.03%
Winner
TKNO
+269.00%
1Y
UPB
-62.77%
Winner
TKNO
+51.23%
5Y(CAGR)
UPB
N/A
TKNO
-17.54%
Max(CAGR)
UPB
-46.76%
Winner
TKNO
-21.15%
UPB vs TKNO - Annual Returns (2021 - 2026)
Returns include dividend reinvestment.
| Year | UPB | TKNO |
|---|---|---|
| 2026 | -74.47% | +89.23% |
| 2025 | +66.56% | -54.33% |
| 2024 | -25.27% | +119.74% |
| 2023 | N/A | -33.63% |
| 2022 | N/A | -73.94% |
| 2021 | N/A | -18.08% |
UPB vs TKNO Drawdown Comparison
The maximum drawdown for UPB was -81.84%, occurring on Jun 16, 2026. This drawdown has not yet recovered.
The maximum drawdown for TKNO was -95.71%, occurring on Jul 5, 2024. This drawdown has not yet recovered.
The current UPB drawdown is -78.80%. The current TKNO drawdown is -73.62%.
| Rank | UPB | TKNO |
|---|---|---|
| #1 | -81.84% Jan 13, 2026 - Jun 16, 2026 | -95.71% Jun 28, 2021 - Jul 5, 2024 |
| #2 | -77.84% Nov 5, 2024 - Nov 25, 2025 | N/A |
| #3 | -14.99% Dec 22, 2025 - Jan 12, 2026 | N/A |
| #4 | -13.70% Dec 1, 2025 - Dec 16, 2025 | N/A |
| #5 | -6.45% Oct 21, 2024 - Nov 5, 2024 | N/A |
| #6 | -3.38% Dec 16, 2025 - Dec 18, 2025 | N/A |
| #7 | -2.88% Nov 25, 2025 - Dec 1, 2025 | N/A |
| #8 | -1.71% Dec 18, 2025 - Dec 22, 2025 | N/A |
| #9 | -1.63% Oct 14, 2024 - Oct 16, 2024 | N/A |
| #10 | -0.13% Oct 16, 2024 - Oct 18, 2024 | N/A |
Correlation
Correlation between UPB and TKNO is -0.14 which considered as a very weak or no correlation - the stocks move independently of each other.
-0.14
-101
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