TYRA vs ANAB

Comparison between Tyra Biosciences Inc (TYRA, Company) and AnaptysBio Inc (ANAB, Company).

Both TYRA and ANAB are from the Healthcare sector.

5-Year PerformanceANAB has outperformed TYRA, delivering a return of +28.2% compared to +0.8%

TYRA vs ANAB - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TYRA(COMPANY)	ANAB(COMPANY)
Market Cap	$1.51B	$1.51B
Max Drawdown	83.22%	92.08%
Sharpe Ratio	1.73	2.13
5Y Beta	1.04	0.81
Industry	Biotechnology	Biotechnology
P/E Ratio	-10.69	-58.95
PEG Ratio	-0.37	0.00
5Y EPS CAGR	N/A	-4.15%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-6.78%	0.29%
P/S Ratio	N/A	6.63
P/B Ratio	3.90	117.87

Market Cap

TYRA

$1.51B

Winner

ANAB

$1.51B

Max Drawdown

Winner

TYRA

83.22%

ANAB

92.08%

Sharpe Ratio

TYRA

1.73

Winner

ANAB

2.13

5Y Beta

TYRA

1.04

Winner

ANAB

0.81

Industry

TYRA

Biotechnology

ANAB

Biotechnology

P/E Ratio

TYRA

-10.69

Winner

ANAB

-58.95

PEG Ratio

Winner

TYRA

-0.37

ANAB

0.00

5Y EPS CAGR

TYRA

N/A

ANAB

-4.15%

Debt to Equity

TYRA

0.00%

ANAB

0.00%

Free Cash Flow Yield

TYRA

-6.78%

Winner

ANAB

0.29%

P/S Ratio

TYRA

N/A

ANAB

6.63

P/B Ratio

Winner

TYRA

3.90

ANAB

117.87

TYRA vs ANAB - Historical Returns

Returns include dividend reinvestment.

Period	TYRA	ANAB
1 month	-22.60%	-14.50%
3 months	-25.03%	+31.85%
6 months	+19.27%	+87.15%
1 year	+161.28%	+259.27%
5 years(CAGR)	+0.79%	+28.19%
10 years(CAGR)	N/A	+18.60%
Max(CAGR)	+0.79%	+18.60%

TYRA

-22.60%

Winner

ANAB

-14.50%

TYRA

-25.03%

Winner

ANAB

+31.85%

TYRA

+19.27%

Winner

ANAB

+87.15%

TYRA

+161.28%

Winner

ANAB

+259.27%

5Y(CAGR)

TYRA

+0.79%

Winner

ANAB

+28.19%

10Y(CAGR)

TYRA

N/A

ANAB

+18.60%

Max(CAGR)

TYRA

+0.79%

Winner

ANAB

+18.60%

TYRA vs ANAB - Annual Returns (2017 - 2026)

Returns include dividend reinvestment.

Year	TYRA	ANAB
2026	+0.75%	+87.11%
2025	+82.19%	+262.87%
2024	-1.00%	-38.99%
2023	+95.90%	-26.69%
2022	-46.06%	-13.77%
2021	-45.88%	+48.76%
2020	N/A	+35.31%
2019	N/A	-74.50%
2018	N/A	-36.58%
2017	N/A	+492.47%

TYRA vs ANAB Drawdown Comparison

The maximum drawdown for TYRA was -83.22%, occurring on Jun 17, 2022. Recovery took 1058 trading sessions.

The maximum drawdown for ANAB was -92.08%, occurring on Nov 8, 2019. This drawdown has not yet recovered.

The current TYRA drawdown is -31.86%. The current ANAB drawdown is -34.57%.

Rank	TYRA	ANAB
#1	-83.22% Nov 4, 2021 - Jan 27, 2026	-92.08% Mar 2, 2018 - Nov 8, 2019
#2	-48.23% Sep 15, 2021 - Nov 3, 2021	-32.97% Mar 30, 2017 - Jul 24, 2017
#3	-35.82% Apr 2, 2026 - Jun 10, 2026	-32.31% Jul 24, 2017 - Sep 6, 2017
#4	-13.45% Jan 29, 2026 - Feb 23, 2026	-14.04% Jan 24, 2018 - Feb 14, 2018
#5	-9.38% Mar 19, 2026 - Mar 31, 2026	-10.40% Oct 12, 2017 - Nov 13, 2017
#6	-5.74% Feb 25, 2026 - Mar 4, 2026	-7.89% Feb 24, 2017 - Mar 13, 2017
#7	-4.31% Mar 4, 2026 - Mar 11, 2026	-5.75% Sep 18, 2017 - Oct 5, 2017
#8	-1.48% Mar 11, 2026 - Mar 16, 2026	-5.55% Feb 16, 2018 - Mar 2, 2018
#9	-1.02% Jan 27, 2026 - Jan 29, 2026	-5.19% Jan 27, 2017 - Feb 6, 2017
#10	-0.05% Mar 31, 2026 - Apr 2, 2026	-4.41% Feb 14, 2017 - Feb 17, 2017
#11	N/A	-4.06% Dec 4, 2017 - Dec 7, 2017
#12	N/A	-3.94% Feb 14, 2018 - Feb 16, 2018
#13	N/A	-3.50% Sep 13, 2017 - Sep 18, 2017
#14	N/A	-3.10% Feb 17, 2017 - Feb 24, 2017
#15	N/A	-2.64% Oct 5, 2017 - Oct 10, 2017