TXMD vs VTGN

Comparison between TherapeuticsMD Inc (TXMD, Company) and VistaGen Therapeutics Inc (VTGN, Company).

Both TXMD and VTGN are from the Healthcare sector.

5-Year PerformanceTXMD has outperformed VTGN, delivering a return of -48.1% compared to -61.9%

TXMD vs VTGN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TXMD(COMPANY)	VTGN(COMPANY)
Market Cap	$26M	$26M
Max Drawdown	99.89%	99.76%
Sharpe Ratio	1.31	-0.11
5Y Beta	0.63	0.97
Industry	Drug Manufacturers - Specialty & Generic	Biotechnology
P/E Ratio	146.78	-0.36
Forward P/E	2.33	N/A
PEG Ratio	N/A	-0.01
5Y EPS CAGR	N/A	-12.57%
Debt to Equity	0.00%	0.00%

Market Cap

Winner

TXMD

$26M

VTGN

$26M

Max Drawdown

TXMD

99.89%

Winner

VTGN

99.76%

Sharpe Ratio

Winner

TXMD

1.31

VTGN

-0.11

5Y Beta

Winner

TXMD

0.63

VTGN

0.97

Industry

TXMD

Drug Manufacturers - Specialty & Generic

VTGN

Biotechnology

P/E Ratio

TXMD

146.78

Winner

VTGN

-0.36

Forward P/E

TXMD

2.33

VTGN

N/A

PEG Ratio

TXMD

N/A

VTGN

-0.01

5Y EPS CAGR

TXMD

N/A

VTGN

-12.57%

Debt to Equity

TXMD

0.00%

VTGN

0.00%

TXMD vs VTGN - Historical Returns

Returns include dividend reinvestment.

Period	TXMD	VTGN
1 month	+12.38%	+15.87%
3 months	+1.79%	+6.75%
6 months	+35.93%	-19.86%
1 year	+102.68%	-71.01%
5 years(CAGR)	-48.14%	-61.95%
10 years(CAGR)	-40.67%	-39.49%
Max(CAGR)	-9.38%	-43.19%

TXMD

+12.38%

Winner

VTGN

+15.87%

TXMD

+1.79%

Winner

VTGN

+6.75%

Winner

TXMD

+35.93%

VTGN

-19.86%

Winner

TXMD

+102.68%

VTGN

-71.01%

5Y(CAGR)

Winner

TXMD

-48.14%

VTGN

-61.95%

10Y(CAGR)

TXMD

-40.67%

Winner

VTGN

-39.49%

Max(CAGR)

Winner

TXMD

-9.38%

VTGN

-43.19%

TXMD vs VTGN - Annual Returns (2003 - 2026)

Returns include dividend reinvestment.

Year	TXMD	VTGN
2026	+37.58%	+1.62%
2025	+3.82%	-80.03%
2024	-63.09%	-42.72%
2023	-64.00%	+31.79%
2022	-71.60%	-95.07%
2021	-71.33%	-14.85%
2020	-50.41%	+158.67%
2019	-37.63%	-56.60%
2018	-39.23%	+29.31%
2017	+1.17%	-70.26%
2016	-41.18%	-46.71%
2015	+136.22%	N/A
2014	-10.82%	N/A
2013	+60.31%	N/A
2012	+82.35%	N/A
2011	+4738.71%	N/A
2010	-98.00%	N/A
2009	+160.00%	N/A
2008	+48.52%	N/A
2007	-59.44%	N/A
2006	+33.33%	N/A
2005	+48.52%	N/A
2004	-8.18%	N/A
2003	-12.00%	N/A

TXMD vs VTGN Drawdown Comparison

The maximum drawdown for TXMD was -99.89%, occurring on Aug 24, 2011. Recovery took 1071 trading sessions.

The maximum drawdown for VTGN was -99.76%, occurring on Feb 5, 2026. This drawdown has not yet recovered.

The current TXMD drawdown is -99.59%. The current VTGN drawdown is -99.67%.

Rank	TXMD	VTGN
#1	-99.89% Jul 27, 2009 - Oct 25, 2013	-99.76% May 6, 2016 - Feb 5, 2026
#2	-99.87% Dec 29, 2015 - Mar 14, 2025	N/A
#3	-85.43% Mar 1, 2007 - Jul 21, 2009	N/A
#4	-80.00% Dec 11, 2003 - Jun 29, 2004	N/A
#5	-56.96% Mar 18, 2014 - Jun 5, 2015	N/A
#6	-53.02% Nov 24, 2004 - Apr 4, 2006	N/A
#7	-36.59% Jul 23, 2015 - Dec 8, 2015	N/A
#8	-31.82% Apr 4, 2006 - Dec 20, 2006	N/A
#9	-27.27% Feb 9, 2007 - Mar 1, 2007	N/A
#10	-25.10% Oct 28, 2013 - Dec 24, 2013	N/A
#11	-19.60% Jan 9, 2007 - Feb 9, 2007	N/A
#12	-11.11% Dec 20, 2006 - Jan 3, 2007	N/A
#13	-10.98% Jan 30, 2014 - Feb 27, 2014	N/A
#14	-8.69% Jun 5, 2015 - Jul 1, 2015	N/A
#15	-7.76% Dec 26, 2013 - Jan 10, 2014	N/A