TXMD vs AYTU

Comparison between TherapeuticsMD Inc (TXMD, Company) and Aytu BioPharma Inc (AYTU, Company).

Both TXMD and AYTU are from the Healthcare sector.

5-Year PerformanceTXMD has outperformed AYTU, delivering a return of -47.6% compared to -51.8%

TXMD vs AYTU - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TXMD(COMPANY)	AYTU(COMPANY)
Market Cap	$23M	$23M
Max Drawdown	99.89%	100.00%
Sharpe Ratio	1.07	-0.23
5Y Beta	0.59	0.00
Industry	Drug Manufacturers - Specialty & Generic	Drug Manufacturers - Specialty & Generic
P/E Ratio	130.61	-0.61
Forward P/E	2.33	25.77
PEG Ratio	-0.73	0.00
5Y EPS CAGR	N/A	-32.17%
Debt to Equity	0.00%	32.46%
Free Cash Flow Yield	N/A	6.18%
P/S Ratio	6.97	0.41
P/B Ratio	0.89	0.67

Market Cap

Winner

TXMD

$23M

AYTU

$23M

Max Drawdown

Winner

TXMD

99.89%

AYTU

100.00%

Sharpe Ratio

Winner

TXMD

1.07

AYTU

-0.23

5Y Beta

TXMD

0.59

Winner

AYTU

0.00

Industry

TXMD

Drug Manufacturers - Specialty & Generic

AYTU

Drug Manufacturers - Specialty & Generic

P/E Ratio

TXMD

130.61

Winner

AYTU

-0.61

Forward P/E

Winner

TXMD

2.33

AYTU

25.77

PEG Ratio

Winner

TXMD

-0.73

AYTU

0.00

5Y EPS CAGR

TXMD

N/A

AYTU

-32.17%

Debt to Equity

Winner

TXMD

0.00%

AYTU

32.46%

Free Cash Flow Yield

TXMD

N/A

AYTU

6.18%

P/S Ratio

TXMD

6.97

Winner

AYTU

0.41

P/B Ratio

TXMD

0.89

Winner

AYTU

0.67

TXMD vs AYTU - Historical Returns

Returns include dividend reinvestment.

Period	TXMD	AYTU
1 month	-8.04%	-5.02%
3 months	-2.37%	-17.46%
6 months	-10.43%	-19.38%
1 year	+77.59%	-18.11%
5 years(CAGR)	-47.58%	-51.83%
10 years(CAGR)	-40.79%	-67.14%
Max(CAGR)	-9.72%	-67.14%

TXMD

-8.04%

Winner

AYTU

-5.02%

Winner

TXMD

-2.37%

AYTU

-17.46%

Winner

TXMD

-10.43%

AYTU

-19.38%

Winner

TXMD

+77.59%

AYTU

-18.11%

5Y(CAGR)

Winner

TXMD

-47.58%

AYTU

-51.83%

10Y(CAGR)

Winner

TXMD

-40.79%

AYTU

-67.14%

Max(CAGR)

Winner

TXMD

-9.72%

AYTU

-67.14%

TXMD vs AYTU - Annual Returns (2003 - 2026)

Returns include dividend reinvestment.

Year	TXMD	AYTU
2026	+24.85%	-24.91%
2025	+3.82%	+52.76%
2024	-63.09%	-41.18%
2023	-64.00%	-28.03%
2022	-71.60%	-87.81%
2021	-71.33%	-78.33%
2020	-50.41%	-42.50%
2019	-37.63%	+21.23%
2018	-39.23%	-98.28%
2017	+1.17%	-88.85%
2016	-41.18%	N/A
2015	+136.22%	N/A
2014	-10.82%	N/A
2013	+60.31%	N/A
2012	+82.35%	N/A
2011	+4738.71%	N/A
2010	-98.00%	N/A
2009	+160.00%	N/A
2008	+48.52%	N/A
2007	-59.44%	N/A
2006	+33.33%	N/A
2005	+48.52%	N/A
2004	-8.18%	N/A
2003	-12.00%	N/A

TXMD vs AYTU Drawdown Comparison

The maximum drawdown for TXMD was -99.89%, occurring on Aug 24, 2011. Recovery took 1071 trading sessions.

The maximum drawdown for AYTU was -100.00%, occurring on Apr 7, 2025. This drawdown has not yet recovered.

The current TXMD drawdown is -99.63%. The current AYTU drawdown is -100.00%.

Rank	TXMD	AYTU
#1	-99.89% Jul 27, 2009 - Oct 25, 2013	-100.00% Feb 8, 2017 - Apr 7, 2025
#2	-99.87% Dec 29, 2015 - Mar 14, 2025	-11.00% Feb 1, 2017 - Feb 8, 2017
#3	-85.43% Mar 1, 2007 - Jul 21, 2009	N/A
#4	-80.00% Dec 11, 2003 - Jun 29, 2004	N/A
#5	-56.96% Mar 18, 2014 - Jun 5, 2015	N/A
#6	-53.02% Nov 24, 2004 - Apr 4, 2006	N/A
#7	-36.59% Jul 23, 2015 - Dec 8, 2015	N/A
#8	-31.82% Apr 4, 2006 - Dec 20, 2006	N/A
#9	-27.27% Feb 9, 2007 - Mar 1, 2007	N/A
#10	-25.10% Oct 28, 2013 - Dec 24, 2013	N/A
#11	-19.60% Jan 9, 2007 - Feb 9, 2007	N/A
#12	-11.11% Dec 20, 2006 - Jan 3, 2007	N/A
#13	-10.98% Jan 30, 2014 - Feb 27, 2014	N/A
#14	-8.69% Jun 5, 2015 - Jul 1, 2015	N/A
#15	-7.76% Dec 26, 2013 - Jan 10, 2014	N/A