TWO vs MLTX

Comparison between Two Harbors Investment Corp (TWO, Company) and MoonLake Immunotherapeutics - Class A (MLTX, Company).

TWO is from the Real Estate sector, while MLTX is from the Healthcare sector.

5-Year PerformanceMLTX has outperformed TWO, delivering a return of +12.2% compared to -3.6%

TWO vs MLTX - Performance Comparison

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Key Characteristics

Financial metrics and valuation ratios

Metric	TWO(COMPANY)	MLTX(COMPANY)
Market Cap	$1.31B	$1.31B
Max Drawdown	92.02%	90.22%
Sharpe Ratio	0.82	0.48
5Y Beta	0.62	0.95
Industry	Reit - Mortgage	Biotechnology
P/E Ratio	-3.79	-5.14
Forward P/E	10.94	N/A
PEG Ratio	2.76	-0.03
Dividend Yield	11.40%	N/A
5Y Dividends CAGR	-7.04%	N/A
Debt to Equity	478.53%	38.98%
Free Cash Flow Yield	2.56%	-17.08%
P/S Ratio	2.67	N/A
P/B Ratio	1.17	5.56

Market Cap

TWO

$1.31B

Winner

MLTX

$1.31B

Max Drawdown

TWO

92.02%

Winner

MLTX

90.22%

Sharpe Ratio

Winner

TWO

0.82

MLTX

0.48

5Y Beta

Winner

TWO

0.62

MLTX

0.95

Industry

TWO

Reit - Mortgage

MLTX

Biotechnology

P/E Ratio

TWO

-3.79

Winner

MLTX

-5.14

Forward P/E

TWO

10.94

MLTX

N/A

PEG Ratio

TWO

2.76

Winner

MLTX

-0.03

Dividend Yield

TWO

11.40%

MLTX

N/A

5Y Dividends CAGR

TWO

-7.04%

MLTX

N/A

Debt to Equity

TWO

478.53%

Winner

MLTX

38.98%

Free Cash Flow Yield

Winner

TWO

2.56%

MLTX

-17.08%

P/S Ratio

TWO

2.67

MLTX

N/A

P/B Ratio

Winner

TWO

1.17

MLTX

5.56

TWO vs MLTX - Historical Returns

Returns include dividend reinvestment.

Period	TWO	MLTX
1 month	+0.65%	+5.23%
3 months	+32.47%	-0.67%
6 months	+28.51%	+20.13%
1 year	+32.43%	-63.34%
5 years(CAGR)	-3.62%	+12.23%
10 years(CAGR)	-3.60%	N/A
Max(CAGR)	+2.40%	+9.97%

TWO

+0.65%

Winner

MLTX

+5.23%

Winner

TWO

+32.47%

MLTX

-0.67%

Winner

TWO

+28.51%

MLTX

+20.13%

Winner

TWO

+32.43%

MLTX

-63.34%

5Y(CAGR)

TWO

-3.62%

Winner

MLTX

+12.23%

10Y(CAGR)

TWO

-3.60%

MLTX

N/A

Max(CAGR)

TWO

+2.40%

Winner

MLTX

+9.97%

TWO vs MLTX - Annual Returns (2009 - 2026)

Returns include dividend reinvestment.

Year	TWO	MLTX
2026	+24.13%	+49.79%
2025	+1.39%	-75.40%
2024	-2.38%	-9.07%
2023	-0.24%	+447.76%
2022	-25.38%	+5.85%
2021	+3.15%	-8.76%
2020	-52.49%	+8.39%
2019	+27.18%	N/A
2018	-9.54%	N/A
2017	+13.91%	N/A
2016	+18.53%	N/A
2015	-11.36%	N/A
2014	+17.20%	N/A
2013	-10.10%	N/A
2012	+39.18%	N/A
2011	+15.17%	N/A
2010	+17.22%	N/A
2009	+3.87%	N/A

TWO vs MLTX Drawdown Comparison

The maximum drawdown for TWO was -84.71%, occurring on Apr 3, 2020. This drawdown has not yet recovered.

The maximum drawdown for MLTX was -90.22%, occurring on Sep 29, 2025. This drawdown has not yet recovered.

The current TWO drawdown is -56.53%. The current MLTX drawdown is -71.97%.

Rank	TWO	MLTX
#1	-84.71% Feb 20, 2020 - Apr 3, 2020	-90.22% Feb 12, 2024 - Sep 29, 2025
#2	-31.39% Mar 26, 2013 - Feb 16, 2017	-64.60% Apr 5, 2022 - Feb 7, 2023
#3	-21.96% Oct 5, 2017 - Nov 8, 2019	-41.80% Oct 5, 2023 - Dec 27, 2023
#4	-20.98% Jul 6, 2011 - Feb 17, 2012	-25.65% Feb 18, 2021 - Apr 5, 2022
#5	-16.18% Oct 8, 2012 - Jan 2, 2013	-19.79% Mar 8, 2023 - Apr 24, 2023
#6	-13.53% Jan 4, 2010 - Sep 13, 2010	-18.38% Jul 28, 2023 - Oct 5, 2023
#7	-9.39% Oct 30, 2009 - Dec 8, 2009	-15.06% Dec 27, 2023 - Feb 9, 2024
#8	-7.76% Mar 9, 2011 - May 19, 2011	-14.12% Apr 24, 2023 - May 4, 2023
#9	-5.83% Jun 19, 2017 - Aug 31, 2017	-12.27% Jun 9, 2023 - Jun 26, 2023
#10	-4.86% Apr 27, 2012 - Jun 13, 2012	-7.95% Jul 19, 2023 - Jul 26, 2023
#11	-4.55% Apr 27, 2017 - Jun 1, 2017	-7.48% Jul 5, 2023 - Jul 14, 2023
#12	-4.05% May 19, 2011 - Jun 22, 2011	-5.83% Oct 22, 2020 - Dec 1, 2020
#13	-4.04% Dec 8, 2009 - Dec 30, 2009	-5.45% May 10, 2023 - May 25, 2023
#14	-3.91% Feb 19, 2013 - Feb 28, 2013	-5.45% Dec 31, 2020 - Jan 8, 2021
#15	-3.66% Dec 13, 2010 - Dec 30, 2010	-4.78% Jan 8, 2021 - Feb 11, 2021

Correlation

Correlation between TWO and MLTX is -0.53 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.53

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