TSHA vs SAM

Comparison between Taysha Gene Therapies Inc (TSHA, Company) and Boston Beer Co. Inc - Class A (SAM, Company).

TSHA is from the Healthcare sector, while SAM is from the Consumer Defensive sector.

5-Year PerformanceTSHA has outperformed SAM, delivering a return of -22.6% compared to -28.7%

TSHA vs SAM - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TSHA(COMPANY)	SAM(COMPANY)
Market Cap	$1.78B	$1.78B
Max Drawdown	98.14%	87.67%
Sharpe Ratio	1.24	-0.20
5Y Beta	1.42	0.29
Industry	Biotechnology	Beverages - Brewers
P/E Ratio	-13.36	-84.49
Forward P/E	N/A	17.99
PEG Ratio	-1.48	0.78
Debt to Equity	23.10%	0.00%
Free Cash Flow Yield	-6.34%	10.72%
P/S Ratio	238.09	0.98
P/B Ratio	7.72	2.59

Market Cap

TSHA

$1.78B

Winner

SAM

$1.78B

Max Drawdown

TSHA

98.14%

Winner

SAM

87.67%

Sharpe Ratio

Winner

TSHA

1.24

SAM

-0.20

5Y Beta

TSHA

1.42

Winner

SAM

0.29

Industry

TSHA

Biotechnology

SAM

Beverages - Brewers

P/E Ratio

TSHA

-13.36

Winner

SAM

-84.49

Forward P/E

TSHA

N/A

SAM

17.99

PEG Ratio

Winner

TSHA

-1.48

SAM

0.78

Debt to Equity

TSHA

23.10%

Winner

SAM

0.00%

Free Cash Flow Yield

TSHA

-6.34%

Winner

SAM

10.72%

P/S Ratio

TSHA

238.09

Winner

SAM

0.98

P/B Ratio

TSHA

7.72

Winner

SAM

2.59

TSHA vs SAM - Historical Returns

Returns include dividend reinvestment.

Period	TSHA	SAM
1 month	-13.17%	-3.73%
3 months	-8.84%	-30.10%
6 months	+18.62%	-23.07%
1 year	+124.11%	-11.97%
5 years(CAGR)	-22.56%	-28.74%
10 years(CAGR)	N/A	+0.37%
Max(CAGR)	-21.99%	+12.28%

TSHA

-13.17%

Winner

SAM

-3.73%

Winner

TSHA

-8.84%

SAM

-30.10%

Winner

TSHA

+18.62%

SAM

-23.07%

Winner

TSHA

+124.11%

SAM

-11.97%

5Y(CAGR)

Winner

TSHA

-22.56%

SAM

-28.74%

10Y(CAGR)

TSHA

N/A

SAM

+0.37%

Max(CAGR)

TSHA

-21.99%

Winner

SAM

+12.28%

TSHA vs SAM - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	TSHA	SAM
2026	+8.00%	-14.44%
2025	+197.30%	-35.23%
2024	+1.17%	-11.62%
2023	-19.55%	+7.12%
2022	-80.94%	-36.66%
2021	-55.48%	-46.96%
2020	+10.31%	+167.92%
2019	N/A	+60.77%
2018	N/A	+26.76%
2017	N/A	+12.15%
2016	N/A	-14.76%
2015	N/A	-27.96%
2014	N/A	+30.35%
2013	N/A	+73.40%
2012	N/A	+28.26%
2011	N/A	+12.09%
2010	N/A	+100.06%
2009	N/A	+63.22%
2008	N/A	-21.20%
2007	N/A	+4.12%
2006	N/A	+44.21%
2005	N/A	+19.33%
2004	N/A	+16.55%
2003	N/A	+26.85%
2002	N/A	-10.62%
2001	N/A	+96.00%
2000	N/A	+24.79%
1999	N/A	-7.23%

TSHA vs SAM Drawdown Comparison

The maximum drawdown for TSHA was -98.14%, occurring on Jun 28, 2023. This drawdown has not yet recovered.

The maximum drawdown for SAM was -87.67%, occurring on Jun 4, 2026. This drawdown has not yet recovered.

The current TSHA drawdown is -82.14%. The current SAM drawdown is -86.91%.

Rank	TSHA	SAM
#1	-98.14% Jan 20, 2021 - Jun 28, 2023	-87.67% Apr 20, 2021 - Jun 4, 2026
#2	-21.78% Sep 25, 2020 - Dec 23, 2020	-66.19% Oct 17, 2007 - Apr 13, 2010
#3	-10.74% Dec 23, 2020 - Jan 14, 2021	-59.91% Jan 22, 2015 - Jul 13, 2018
#4	N/A	-36.14% Nov 14, 2002 - Nov 12, 2003
#5	N/A	-30.59% Aug 27, 2019 - Apr 27, 2020
#6	N/A	-29.68% Dec 27, 2001 - Nov 14, 2002
#7	N/A	-28.64% Jul 23, 2018 - May 3, 2019
#8	N/A	-27.80% Aug 23, 2004 - Jun 22, 2006
#9	N/A	-27.53% Dec 21, 2010 - Nov 3, 2011
#10	N/A	-21.38% Oct 21, 2013 - Nov 10, 2014
#11	N/A	-21.11% Jul 5, 2012 - Dec 13, 2012
#12	N/A	-20.92% Sep 8, 2000 - Feb 15, 2001
#13	N/A	-18.04% Oct 23, 2020 - Feb 5, 2021
#14	N/A	-17.51% Dec 11, 2006 - May 22, 2007
#15	N/A	-17.32% Dec 11, 2001 - Dec 20, 2001