TRVI vs CLDX

Comparison between Trevi Therapeutics Inc (TRVI, Company) and Celldex Therapeutics Inc (CLDX, Company).

Both TRVI and CLDX are from the Healthcare sector.

5-Year PerformanceTRVI has outperformed CLDX, delivering a return of +52.6% compared to +1.6%

TRVI vs CLDX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TRVI(COMPANY)	CLDX(COMPANY)
Market Cap	$2.25B	$2.25B
Max Drawdown	95.45%	99.95%
Sharpe Ratio	2.16	1.09
5Y Beta	0.63	1.14
Industry	Biotechnology	Biotechnology
P/E Ratio	-48.58	-7.92
PEG Ratio	N/A	-0.14
5Y EPS CAGR	-27.09%	21.48%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-2.02%	-10.06%
P/S Ratio	N/A	3065.27
P/B Ratio	14.45	5.82

Market Cap

Winner

TRVI

$2.25B

CLDX

$2.25B

Max Drawdown

Winner

TRVI

95.45%

CLDX

99.95%

Sharpe Ratio

Winner

TRVI

2.16

CLDX

1.09

5Y Beta

Winner

TRVI

0.63

CLDX

1.14

Industry

TRVI

Biotechnology

CLDX

Biotechnology

P/E Ratio

Winner

TRVI

-48.58

CLDX

-7.92

PEG Ratio

TRVI

N/A

CLDX

-0.14

5Y EPS CAGR

TRVI

-27.09%

Winner

CLDX

21.48%

Debt to Equity

TRVI

0.00%

CLDX

0.00%

Free Cash Flow Yield

Winner

TRVI

-2.02%

CLDX

-10.06%

P/S Ratio

TRVI

N/A

CLDX

3065.27

P/B Ratio

TRVI

14.45

Winner

CLDX

5.82

TRVI vs CLDX - Historical Returns

Returns include dividend reinvestment.

Period	TRVI	CLDX
1 month	+26.22%	+14.29%
3 months	+53.81%	+11.06%
6 months	+41.25%	+33.56%
1 year	+220.67%	+66.56%
5 years(CAGR)	+52.62%	+1.64%
10 years(CAGR)	N/A	-5.39%
Max(CAGR)	+12.38%	-8.35%

Winner

TRVI

+26.22%

CLDX

+14.29%

Winner

TRVI

+53.81%

CLDX

+11.06%

Winner

TRVI

+41.25%

CLDX

+33.56%

Winner

TRVI

+220.67%

CLDX

+66.56%

5Y(CAGR)

Winner

TRVI

+52.62%

CLDX

+1.64%

10Y(CAGR)

TRVI

N/A

CLDX

-5.39%

Max(CAGR)

Winner

TRVI

+12.38%

CLDX

-8.35%

TRVI vs CLDX - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	TRVI	CLDX
2026	+52.65%	+30.54%
2025	+187.16%	+5.31%
2024	+216.92%	-37.47%
2023	-33.99%	-8.60%
2022	+144.30%	+13.76%
2021	-70.48%	+102.30%
2020	-35.47%	+678.67%
2019	-52.47%	-40.68%
2018	N/A	-93.22%
2017	N/A	-21.33%
2016	N/A	-76.38%
2015	N/A	-14.83%
2014	N/A	-25.84%
2013	N/A	+245.86%
2012	N/A	+141.37%
2011	N/A	-38.39%
2010	N/A	-12.53%
2009	N/A	-41.55%
2008	N/A	+17.86%
2007	N/A	-63.50%
2006	N/A	-28.72%
2005	N/A	-8.29%
2004	N/A	-27.17%
2003	N/A	+134.19%
2002	N/A	-71.25%
2001	N/A	-37.73%
2000	N/A	+197.40%
1999	N/A	+23.50%

TRVI vs CLDX Drawdown Comparison

The maximum drawdown for TRVI was -95.45%, occurring on Feb 23, 2022. Recovery took 1601 trading sessions.

The maximum drawdown for CLDX was -99.95%, occurring on Mar 20, 2020. This drawdown has not yet recovered.

The current CLDX drawdown is -98.83%.

Rank	TRVI	CLDX
#1	-95.45% Jun 3, 2019 - Oct 14, 2025	-99.95% Mar 6, 2000 - Mar 20, 2020
#2	-29.50% Dec 10, 2025 - Apr 15, 2026	-28.28% Nov 29, 1999 - Dec 31, 1999
#3	-14.03% Apr 20, 2026 - Jun 17, 2026	-17.82% Jan 26, 2000 - Feb 8, 2000
#4	-11.98% Nov 11, 2025 - Nov 26, 2025	-17.35% Nov 5, 1999 - Nov 26, 1999
#5	-8.75% Oct 31, 2025 - Nov 10, 2025	-16.60% Dec 31, 1999 - Jan 7, 2000
#6	-5.26% Dec 3, 2025 - Dec 10, 2025	-10.86% Feb 23, 2000 - Mar 1, 2000
#7	-4.10% May 21, 2019 - May 30, 2019	-8.94% Jan 13, 2000 - Jan 20, 2000
#8	-3.58% Oct 22, 2025 - Oct 30, 2025	-5.66% Nov 3, 1999 - Nov 5, 1999
#9	-3.51% May 10, 2019 - May 14, 2019	-5.41% Feb 11, 2000 - Feb 17, 2000
#10	-3.37% May 14, 2019 - May 20, 2019	-4.02% Feb 17, 2000 - Feb 22, 2000
#11	-2.54% Oct 16, 2025 - Oct 20, 2025	-4.00% Jan 24, 2000 - Jan 26, 2000
#12	-1.86% Jun 22, 2026 - Jun 25, 2026	N/A
#13	-1.58% May 8, 2019 - May 10, 2019	N/A
#14	-0.75% Nov 26, 2025 - Dec 1, 2025	N/A
#15	-0.37% Oct 20, 2025 - Oct 22, 2025	N/A