TRVI vs AXGN

Comparison between Trevi Therapeutics Inc (TRVI, Company) and Axogen Inc (AXGN, Company).

Both TRVI and AXGN are from the Healthcare sector.

5-Year PerformanceTRVI has outperformed AXGN, delivering a return of +52.6% compared to +15.3%

TRVI vs AXGN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TRVI(COMPANY)	AXGN(COMPANY)
Market Cap	$2.25B	$2.26B
Max Drawdown	95.45%	95.37%
Sharpe Ratio	2.16	2.94
5Y Beta	0.63	0.87
Industry	Biotechnology	Medical Devices
P/E Ratio	-48.58	-68.67
Forward P/E	N/A	384.62
PEG Ratio	N/A	-0.24
5Y EPS CAGR	-27.09%	2.38%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-2.02%	0.41%
P/S Ratio	N/A	9.50
P/B Ratio	14.45	9.25

Market Cap

TRVI

$2.25B

Winner

AXGN

$2.26B

Max Drawdown

TRVI

95.45%

Winner

AXGN

95.37%

Sharpe Ratio

TRVI

2.16

Winner

AXGN

2.94

5Y Beta

Winner

TRVI

0.63

AXGN

0.87

Industry

TRVI

Biotechnology

AXGN

Medical Devices

P/E Ratio

TRVI

-48.58

Winner

AXGN

-68.67

Forward P/E

TRVI

N/A

AXGN

384.62

PEG Ratio

TRVI

N/A

AXGN

-0.24

5Y EPS CAGR

TRVI

-27.09%

Winner

AXGN

2.38%

Debt to Equity

TRVI

0.00%

AXGN

0.00%

Free Cash Flow Yield

TRVI

-2.02%

Winner

AXGN

0.41%

P/S Ratio

TRVI

N/A

AXGN

9.50

P/B Ratio

TRVI

14.45

Winner

AXGN

9.25

TRVI vs AXGN - Historical Returns

Returns include dividend reinvestment.

Period	TRVI	AXGN
1 month	+26.22%	+8.40%
3 months	+53.81%	+39.32%
6 months	+41.25%	+36.98%
1 year	+220.67%	+329.13%
5 years(CAGR)	+52.62%	+15.26%
10 years(CAGR)	N/A	+21.83%
Max(CAGR)	+12.38%	+12.73%

Winner

TRVI

+26.22%

AXGN

+8.40%

Winner

TRVI

+53.81%

AXGN

+39.32%

Winner

TRVI

+41.25%

AXGN

+36.98%

TRVI

+220.67%

Winner

AXGN

+329.13%

5Y(CAGR)

Winner

TRVI

+52.62%

AXGN

+15.26%

10Y(CAGR)

TRVI

N/A

AXGN

+21.83%

Max(CAGR)

TRVI

+12.38%

Winner

AXGN

+12.73%

TRVI vs AXGN - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	TRVI	AXGN
2026	+52.65%	+44.94%
2025	+187.16%	+99.57%
2024	+216.92%	+138.49%
2023	-33.99%	-30.87%
2022	+144.30%	+0.00%
2021	-70.48%	-46.49%
2020	-35.47%	+3.23%
2019	-52.47%	-13.28%
2018	N/A	-26.91%
2017	N/A	+217.98%
2016	N/A	+78.22%
2015	N/A	+38.89%
2014	N/A	-25.36%
2013	N/A	+63.27%
2012	N/A	+3.85%
2011	N/A	-32.50%
2010	N/A	+2.78%
2009	N/A	+46.18%
2008	N/A	+111.54%
2007	N/A	+52.94%
2006	N/A	+27.45%
2005	N/A	-65.11%
2004	N/A	+114.29%
2003	N/A	+65.31%
2002	N/A	-68.71%
2001	N/A	-30.85%
2000	N/A	+25.00%
1999	N/A	-29.74%

TRVI vs AXGN Drawdown Comparison

The maximum drawdown for TRVI was -95.45%, occurring on Feb 23, 2022. Recovery took 1601 trading sessions.

The maximum drawdown for AXGN was -95.37%, occurring on Aug 16, 2002. Recovery took 1825 trading sessions.

The current AXGN drawdown is -19.62%.

Rank	TRVI	AXGN
#1	-95.45% Jun 3, 2019 - Oct 14, 2025	-95.37% Mar 27, 2000 - Jul 2, 2007
#2	-29.50% Dec 10, 2025 - Apr 15, 2026	-93.54% Jul 23, 2018 - Nov 1, 2023
#3	-14.03% Apr 20, 2026 - Jun 17, 2026	-82.67% Jul 5, 2007 - Jun 21, 2016
#4	-11.98% Nov 11, 2025 - Nov 26, 2025	-49.98% Nov 9, 1999 - Jan 14, 2000
#5	-8.75% Oct 31, 2025 - Nov 10, 2025	-36.67% Jan 14, 2000 - Mar 24, 2000
#6	-5.26% Dec 3, 2025 - Dec 10, 2025	-21.42% Jan 5, 2018 - Feb 27, 2018
#7	-4.10% May 21, 2019 - May 30, 2019	-17.43% Jul 11, 2016 - Aug 4, 2016
#8	-3.58% Oct 22, 2025 - Oct 30, 2025	-16.67% Sep 8, 2016 - Jan 9, 2017
#9	-3.51% May 10, 2019 - May 14, 2019	-13.57% Jul 21, 2017 - Aug 29, 2017
#10	-3.37% May 14, 2019 - May 20, 2019	-11.10% Nov 4, 1999 - Nov 9, 1999
#11	-2.54% Oct 16, 2025 - Oct 20, 2025	-11.01% Jan 31, 2017 - Apr 12, 2017
#12	-1.86% Jun 22, 2026 - Jun 25, 2026	-10.19% Mar 26, 2018 - Apr 18, 2018
#13	-1.58% May 8, 2019 - May 10, 2019	-9.78% Nov 10, 2017 - Nov 21, 2017
#14	-0.75% Nov 26, 2025 - Dec 1, 2025	-8.20% May 1, 2017 - May 12, 2017
#15	-0.37% Oct 20, 2025 - Oct 22, 2025	-7.57% Jun 8, 2017 - Jun 30, 2017