TNGX vs MKTX

Comparison between Tango Therapeutics Inc (TNGX, Company) and MarketAxess Holdings Inc (MKTX, Company).

TNGX is from the Healthcare sector, while MKTX is from the Financial Services sector.

5-Year PerformanceTNGX has outperformed MKTX, delivering a return of +23.0% compared to -21.8%

TNGX vs MKTX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TNGX(COMPANY)	MKTX(COMPANY)
Market Cap	$4.13B	$4.13B
Max Drawdown	93.64%	80.60%
Sharpe Ratio	2.32	-2.38
5Y Beta	1.39	-0.14
Industry	Biotechnology	Capital Markets
P/E Ratio	-35.46	13.65
Forward P/E	N/A	14.33
PEG Ratio	N/A	0.28
Dividend Yield	N/A	2.63%
5Y Dividends CAGR	N/A	8.79%
5Y EPS CAGR	N/A	1.15%
Debt to Equity	0.00%	19.17%
Free Cash Flow Yield	-3.45%	6.56%
P/S Ratio	73.25	4.75
P/B Ratio	10.60	3.48

Market Cap

Winner

TNGX

$4.13B

MKTX

$4.13B

Max Drawdown

TNGX

93.64%

Winner

MKTX

80.60%

Sharpe Ratio

Winner

TNGX

2.32

MKTX

-2.38

5Y Beta

TNGX

1.39

Winner

MKTX

-0.14

Industry

TNGX

Biotechnology

MKTX

Capital Markets

P/E Ratio

Winner

TNGX

-35.46

MKTX

13.65

Forward P/E

TNGX

N/A

MKTX

14.33

PEG Ratio

TNGX

N/A

MKTX

0.28

Dividend Yield

TNGX

N/A

MKTX

2.63%

5Y Dividends CAGR

TNGX

N/A

MKTX

8.79%

5Y EPS CAGR

TNGX

N/A

MKTX

1.15%

Debt to Equity

Winner

TNGX

0.00%

MKTX

19.17%

Free Cash Flow Yield

TNGX

-3.45%

Winner

MKTX

6.56%

P/S Ratio

TNGX

73.25

Winner

MKTX

4.75

P/B Ratio

TNGX

10.60

Winner

MKTX

3.48

TNGX vs MKTX - Historical Returns

Returns include dividend reinvestment.

Period	TNGX	MKTX
1 month	+31.66%	-14.00%
3 months	+80.41%	-33.01%
6 months	+230.91%	-31.78%
1 year	+512.67%	-45.72%
5 years(CAGR)	+22.98%	-21.78%
10 years(CAGR)	N/A	-0.62%
Max(CAGR)	+21.14%	+10.51%

Winner

TNGX

+31.66%

MKTX

-14.00%

Winner

TNGX

+80.41%

MKTX

-33.01%

Winner

TNGX

+230.91%

MKTX

-31.78%

Winner

TNGX

+512.67%

MKTX

-45.72%

5Y(CAGR)

Winner

TNGX

+22.98%

MKTX

-21.78%

10Y(CAGR)

TNGX

N/A

MKTX

-0.62%

Max(CAGR)

Winner

TNGX

+21.14%

MKTX

+10.51%

TNGX vs MKTX - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	TNGX	MKTX
2026	+246.47%	-31.61%
2025	+183.07%	-18.26%
2024	-69.04%	-19.83%
2023	+35.43%	+3.88%
2022	-33.73%	-29.01%
2021	-3.78%	-26.51%
2020	+11.83%	+50.84%
2019	N/A	+82.49%
2018	N/A	+4.66%
2017	N/A	+35.29%
2016	N/A	+35.49%
2015	N/A	+60.05%
2014	N/A	+10.85%
2013	N/A	+86.74%
2012	N/A	+27.24%
2011	N/A	+49.22%
2010	N/A	+49.24%
2009	N/A	+61.04%
2008	N/A	-33.55%
2007	N/A	-4.82%
2006	N/A	+20.94%
2005	N/A	-28.34%
2004	N/A	-2.74%

TNGX vs MKTX Drawdown Comparison

The maximum drawdown for TNGX was -93.64%, occurring on May 8, 2025. Recovery took 1126 trading sessions.

The maximum drawdown for MKTX was -80.60%, occurring on Oct 17, 2008. Recovery took 1549 trading sessions.

The current TNGX drawdown is -1.96%. The current MKTX drawdown is -78.08%.

Rank	TNGX	MKTX
#1	-93.64% Sep 17, 2021 - Mar 16, 2026	-80.60% Nov 22, 2004 - Jan 18, 2011
#2	-29.24% Apr 21, 2026 - Jun 8, 2026	-78.95% Dec 22, 2020 - Jun 10, 2026
#3	-26.94% Feb 22, 2021 - Sep 7, 2021	-32.71% Sep 6, 2019 - Apr 16, 2020
#4	-13.43% Jan 7, 2021 - Feb 22, 2021	-32.34% Nov 21, 2013 - Dec 17, 2014
#5	-9.13% Jun 9, 2026 - Jun 10, 2026	-30.38% Mar 28, 2012 - Jan 2, 2013
#6	-8.46% Apr 2, 2026 - Apr 14, 2026	-22.24% Mar 16, 2018 - Dec 7, 2018
#7	-8.00% Mar 25, 2026 - Mar 31, 2026	-20.10% Aug 29, 2011 - Nov 3, 2011
#8	-6.07% Sep 23, 2020 - Nov 23, 2020	-19.95% Jul 9, 2020 - Oct 20, 2020
#9	-4.65% Dec 1, 2020 - Dec 31, 2020	-16.64% Jun 19, 2017 - Jan 5, 2018
#10	-2.37% Mar 20, 2026 - Mar 24, 2026	-16.39% Apr 7, 2011 - Jul 1, 2011
#11	-1.40% Dec 31, 2020 - Jan 6, 2021	-15.90% Sep 15, 2016 - Jan 25, 2017
#12	-1.37% Sep 4, 2020 - Sep 22, 2020	-15.73% Jul 10, 2015 - Nov 18, 2015
#13	-1.33% Sep 13, 2021 - Sep 15, 2021	-14.71% Nov 3, 2011 - Dec 20, 2011
#14	-1.14% Apr 15, 2026 - Apr 17, 2026	-13.55% Aug 3, 2011 - Aug 17, 2011
#15	-0.94% Apr 17, 2026 - Apr 21, 2026	-13.09% Dec 13, 2018 - Feb 15, 2019