SYRE vs RUSHB

Comparison between Spyre Therapeutics Inc (SYRE, Company) and Rush Enterprises Inc - Class B (RUSHB, Company).

SYRE is from the Healthcare sector, while RUSHB is from the Consumer Cyclical sector.

5-Year PerformanceRUSHB has outperformed SYRE, delivering a return of +23.9% compared to -7.5%

SYRE vs RUSHB - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SYRE(COMPANY)	RUSHB(COMPANY)
Market Cap	$9.17B	$9.20B
Max Drawdown	99.11%	78.89%
Sharpe Ratio	3.05	1.17
5Y Beta	1.79	0.92
Industry	Biotechnology	Auto & Truck Dealerships
P/E Ratio	-45.84	33.66
Forward P/E	N/A	11.57
Dividend Yield	N/A	0.97%
5Y Dividends CAGR	N/A	18.90%
5Y EPS CAGR	-2.73%	13.07%
Debt to Equity	0.00%	12.13%
Free Cash Flow Yield	-2.28%	3.79%

Market Cap

SYRE

$9.17B

Winner

RUSHB

$9.20B

Max Drawdown

SYRE

99.11%

Winner

RUSHB

78.89%

Sharpe Ratio

Winner

SYRE

3.05

RUSHB

1.17

5Y Beta

SYRE

1.79

Winner

RUSHB

0.92

Industry

SYRE

Biotechnology

RUSHB

Auto & Truck Dealerships

P/E Ratio

Winner

SYRE

-45.84

RUSHB

33.66

Forward P/E

SYRE

N/A

RUSHB

11.57

Dividend Yield

SYRE

N/A

RUSHB

0.97%

5Y Dividends CAGR

SYRE

N/A

RUSHB

18.90%

5Y EPS CAGR

SYRE

-2.73%

Winner

RUSHB

13.07%

Debt to Equity

Winner

SYRE

0.00%

RUSHB

12.13%

Free Cash Flow Yield

SYRE

-2.28%

Winner

RUSHB

3.79%

SYRE vs RUSHB - Historical Returns

Returns include dividend reinvestment.

Period	SYRE	RUSHB
1 month	+8.66%	+5.91%
3 months	+33.47%	+24.79%
6 months	+178.05%	+25.72%
1 year	+485.34%	+35.40%
5 years(CAGR)	-7.54%	+23.93%
10 years(CAGR)	-1.21%	+23.67%
Max(CAGR)	-8.10%	+14.45%

Winner

SYRE

+8.66%

RUSHB

+5.91%

Winner

SYRE

+33.47%

RUSHB

+24.79%

Winner

SYRE

+178.05%

RUSHB

+25.72%

Winner

SYRE

+485.34%

RUSHB

+35.40%

5Y(CAGR)

SYRE

-7.54%

Winner

RUSHB

+23.93%

10Y(CAGR)

SYRE

-1.21%

Winner

RUSHB

+23.67%

Max(CAGR)

SYRE

-8.10%

Winner

RUSHB

+14.45%

SYRE vs RUSHB - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	SYRE	RUSHB
2026	+233.06%	+46.62%
2025	+37.36%	+5.88%
2024	+8.79%	+6.11%
2023	+104.27%	+46.37%
2022	-90.57%	+6.09%
2021	-44.51%	+49.29%
2020	+1.55%	+26.75%
2019	-4.98%	+25.96%
2018	+39.22%	-24.56%
2017	+18.38%	+57.91%
2016	-55.48%	+43.11%
2015	N/A	-22.56%
2014	N/A	+15.36%
2013	N/A	+43.26%
2012	N/A	+0.29%
2011	N/A	-6.23%
2010	N/A	+69.04%
2009	N/A	+17.04%
2008	N/A	-53.36%
2007	N/A	+63.80%
2006	N/A	+9.58%
2005	N/A	-14.34%
2004	N/A	+74.14%
2003	N/A	+191.08%
2002	N/A	-5.84%
2001	N/A	+86.40%
2000	N/A	-75.23%
1999	N/A	-4.92%

SYRE vs RUSHB Drawdown Comparison

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The maximum drawdown for RUSHB was -77.95%, occurring on Dec 7, 2000. Recovery took 983 trading sessions.

The current SYRE drawdown is -66.02%. The current RUSHB drawdown is -1.00%.

Rank	SYRE	RUSHB
#1	-99.11% Apr 8, 2016 - Jun 21, 2023	-77.95% Nov 24, 1999 - Oct 24, 2003
#2	N/A	-70.15% Jul 23, 2007 - Dec 3, 2010
#3	N/A	-58.02% Jan 26, 2018 - Oct 23, 2020
#4	N/A	-54.25% Sep 2, 2014 - Feb 21, 2017
#5	N/A	-45.52% Dec 7, 2010 - Feb 9, 2012
#6	N/A	-43.52% Feb 16, 2012 - Feb 15, 2013
#7	N/A	-28.48% Mar 28, 2024 - Nov 6, 2024
#8	N/A	-26.03% Dec 28, 2004 - Mar 13, 2006
#9	N/A	-24.21% Apr 19, 2006 - Feb 14, 2007
#10	N/A	-23.72% Nov 3, 2003 - Jan 7, 2004
#11	N/A	-22.93% Jan 6, 2022 - Aug 15, 2022
#12	N/A	-22.83% Mar 19, 2021 - Sep 29, 2021
#13	N/A	-21.02% Aug 16, 2022 - Feb 1, 2023
#14	N/A	-19.59% Sep 18, 2025 - Dec 10, 2025
#15	N/A	-18.72% Jul 30, 2004 - Oct 20, 2004

Correlation

Correlation between SYRE and RUSHB is -0.70 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.70

-101