SRPT vs TSHA

Comparison between Sarepta Therapeutics Inc (SRPT, Company) and Taysha Gene Therapies Inc (TSHA, Company).

Both SRPT and TSHA are from the Healthcare sector.

5-Year PerformanceTSHA has outperformed SRPT, delivering a return of -20.1% compared to -23.8%

SRPT vs TSHA - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SRPT(COMPANY)	TSHA(COMPANY)
Market Cap	$1.92B	$1.91B
Max Drawdown	98.17%	98.14%
Sharpe Ratio	0.54	1.52
5Y Beta	1.40	1.40
Industry	Biotechnology	Biotechnology
P/E Ratio	5.05	-14.35
Forward P/E	5.30	N/A
PEG Ratio	159.25	-1.59
Debt to Equity	55.69%	23.10%
Free Cash Flow Yield	5.98%	-5.90%
P/S Ratio	0.88	255.78
P/B Ratio	1.28	9.00

Market Cap

Winner

SRPT

$1.92B

TSHA

$1.91B

Max Drawdown

SRPT

98.17%

Winner

TSHA

98.14%

Sharpe Ratio

SRPT

0.54

Winner

TSHA

1.52

5Y Beta

SRPT

1.40

Winner

TSHA

1.40

Industry

SRPT

Biotechnology

TSHA

Biotechnology

P/E Ratio

SRPT

5.05

Winner

TSHA

-14.35

Forward P/E

SRPT

5.30

TSHA

N/A

PEG Ratio

SRPT

159.25

Winner

TSHA

-1.59

Debt to Equity

SRPT

55.69%

Winner

TSHA

23.10%

Free Cash Flow Yield

Winner

SRPT

5.98%

TSHA

-5.90%

P/S Ratio

Winner

SRPT

0.88

TSHA

255.78

P/B Ratio

Winner

SRPT

1.28

TSHA

9.00

SRPT vs TSHA - Historical Returns

Returns include dividend reinvestment.

Period	SRPT	TSHA
1 month	+18.65%	+14.76%
3 months	-17.00%	+49.43%
6 months	-9.53%	+24.38%
1 year	+5.96%	+168.72%
5 years(CAGR)	-23.84%	-20.06%
10 years(CAGR)	-0.49%	N/A
Max(CAGR)	-1.02%	-20.23%

Winner

SRPT

+18.65%

TSHA

+14.76%

SRPT

-17.00%

Winner

TSHA

+49.43%

SRPT

-9.53%

Winner

TSHA

+24.38%

SRPT

+5.96%

Winner

TSHA

+168.72%

5Y(CAGR)

SRPT

-23.84%

Winner

TSHA

-20.06%

10Y(CAGR)

SRPT

-0.49%

TSHA

N/A

Max(CAGR)

Winner

SRPT

-1.02%

TSHA

-20.23%

SRPT vs TSHA - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	SRPT	TSHA
2026	-9.53%	+24.38%
2025	-82.66%	+197.30%
2024	+26.38%	+1.17%
2023	-22.76%	-19.55%
2022	+43.31%	-80.94%
2021	-45.52%	-55.48%
2020	+32.07%	+10.31%
2019	+20.04%	N/A
2018	+87.35%	N/A
2017	+99.28%	N/A
2016	-27.95%	N/A
2015	+158.23%	N/A
2014	-29.69%	N/A
2013	-22.37%	N/A
2012	+481.08%	N/A
2011	-65.67%	N/A
2010	+34.18%	N/A
2009	+114.71%	N/A
2008	-53.66%	N/A
2007	-54.37%	N/A
2006	-6.19%	N/A
2005	+53.33%	N/A
2004	-42.40%	N/A
2003	-16.43%	N/A
2002	-54.71%	N/A
2001	+153.19%	N/A
2000	-17.39%	N/A
1999	+28.89%	N/A

SRPT vs TSHA Drawdown Comparison

The maximum drawdown for SRPT was -98.17%, occurring on Dec 18, 2008. Recovery took 4687 trading sessions.

The maximum drawdown for TSHA was -98.14%, occurring on Jun 28, 2023. This drawdown has not yet recovered.

The current SRPT drawdown is -89.21%. The current TSHA drawdown is -79.43%.

Rank	SRPT	TSHA
#1	-98.17% Feb 9, 2000 - Sep 26, 2018	-98.14% Jan 20, 2021 - Jun 28, 2023
#2	-93.33% Dec 22, 2020 - Jul 25, 2025	-21.78% Sep 25, 2020 - Dec 23, 2020
#3	-54.92% Sep 28, 2018 - Jun 17, 2020	-10.74% Dec 23, 2020 - Jan 14, 2021
#4	-31.03% Nov 8, 1999 - Jan 12, 2000	N/A
#5	-27.14% Jul 20, 2020 - Dec 18, 2020	N/A
#6	-23.03% Jan 27, 2000 - Feb 3, 2000	N/A
#7	-6.62% Jun 22, 2020 - Jul 20, 2020	N/A
#8	-2.34% Jan 13, 2000 - Jan 18, 2000	N/A
#9	-0.73% Nov 1, 1999 - Nov 3, 1999	N/A