SOPH vs SI

Comparison between SOPHiA Genetics SA (SOPH, Company) and Shoulder Innovations Inc (SI, Company).

SOPH vs SI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SOPH(COMPANY)	SI(COMPANY)
Market Cap	$371M	$370M
Max Drawdown	91.35%	31.27%
Sharpe Ratio	1.10	0.65
5Y Beta	1.00	0.69
Industry	Health Information Services	N/A
P/E Ratio	-4.42	-9.14
PEG Ratio	-0.24	N/A
5Y EPS CAGR	6.46%	N/A
Debt to Equity	136.63%	11.25%
Free Cash Flow Yield	-12.23%	-12.37%
P/S Ratio	4.63	6.87
P/B Ratio	8.20	2.79

Market Cap

Winner

SOPH

$371M

$370M

Max Drawdown

SOPH

91.35%

Winner

31.27%

Sharpe Ratio

Winner

SOPH

1.10

0.65

5Y Beta

SOPH

1.00

Winner

0.69

Industry

SOPH

Health Information Services

N/A

P/E Ratio

SOPH

-4.42

Winner

-9.14

PEG Ratio

SOPH

-0.24

N/A

5Y EPS CAGR

SOPH

6.46%

N/A

Debt to Equity

SOPH

136.63%

Winner

11.25%

Free Cash Flow Yield

Winner

SOPH

-12.23%

-12.37%

P/S Ratio

Winner

SOPH

4.63

6.87

P/B Ratio

SOPH

8.20

Winner

2.79

SOPH vs SI - Historical Returns

Returns include dividend reinvestment.

Period	SOPH	SI
1 month	+5.40%	+39.87%
3 months	+6.09%	+27.91%
6 months	+2.74%	+30.13%
1 year	+68.28%	+24.25%
5 years(CAGR)	-22.31%	N/A
Max(CAGR)	-22.31%	+28.53%

SOPH

+5.40%

Winner

+39.87%

SOPH

+6.09%

Winner

+27.91%

SOPH

+2.74%

Winner

+30.13%

Winner

SOPH

+68.28%

+24.25%

5Y(CAGR)

SOPH

-22.31%

N/A

Max(CAGR)

SOPH

-22.31%

Winner

+28.53%

SOPH vs SI - Annual Returns (2021 - 2026)

Returns include dividend reinvestment.

Year	SOPH	SI
2026	+4.50%	+30.13%
2025	+46.39%	-4.98%
2024	-36.44%	N/A
2023	+109.33%	N/A
2022	-85.89%	N/A
2021	-15.87%	N/A

SOPH vs SI Drawdown Comparison

The maximum drawdown for SOPH was -91.35%, occurring on Nov 9, 2022. This drawdown has not yet recovered.

The maximum drawdown for SI was -31.27%, occurring on Nov 10, 2025. Recovery took 61 trading sessions.

The current SOPH drawdown is -75.32%. The current SI drawdown is -0.32%.

Rank	SOPH	SI
#1	-91.35% Aug 31, 2021 - Nov 9, 2022	-31.27% Sep 2, 2025 - Nov 26, 2025
#2	-10.71% Jul 26, 2021 - Aug 3, 2021	-25.30% Dec 16, 2025 - Jun 10, 2026
#3	-7.38% Aug 6, 2021 - Aug 23, 2021	-19.60% Jul 31, 2025 - Aug 27, 2025
#4	-2.69% Aug 23, 2021 - Aug 26, 2021	-10.63% Nov 26, 2025 - Dec 16, 2025
#5	-2.06% Aug 3, 2021 - Aug 6, 2021	-6.09% Aug 27, 2025 - Sep 2, 2025
#6	-0.94% Aug 26, 2021 - Aug 30, 2021	-0.32% Jun 11, 2026 - Jun 12, 2026