SOPH vs MTLS

Comparison between SOPHiA Genetics SA (SOPH, Company) and Materialise Nv (MTLS, Company).

SOPH is from the Healthcare sector, while MTLS is from the Technology sector.

5-Year PerformanceSOPH has outperformed MTLS, delivering a return of -20.2% compared to -22.7%

SOPH vs MTLS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SOPH(COMPANY)	MTLS(COMPANY)
Market Cap	$393M	$391M
Max Drawdown	91.35%	94.84%
Sharpe Ratio	1.15	0.60
5Y Beta	0.98	1.19
Industry	Health Information Services	Software - Application
P/E Ratio	-4.67	32.25
Forward P/E	N/A	625.00
PEG Ratio	-0.26	1.48
5Y EPS CAGR	6.46%	N/A
Debt to Equity	136.63%	23.52%
Free Cash Flow Yield	-11.57%	2.01%

Market Cap

Winner

SOPH

$393M

MTLS

$391M

Max Drawdown

Winner

SOPH

91.35%

MTLS

94.84%

Sharpe Ratio

Winner

SOPH

1.15

MTLS

0.60

5Y Beta

Winner

SOPH

0.98

MTLS

1.19

Industry

SOPH

Health Information Services

MTLS

Software - Application

P/E Ratio

Winner

SOPH

-4.67

MTLS

32.25

Forward P/E

SOPH

N/A

MTLS

625.00

PEG Ratio

Winner

SOPH

-0.26

MTLS

1.48

5Y EPS CAGR

SOPH

6.46%

MTLS

N/A

Debt to Equity

SOPH

136.63%

Winner

MTLS

23.52%

Free Cash Flow Yield

SOPH

-11.57%

Winner

MTLS

2.01%

SOPH vs MTLS - Historical Returns

Returns include dividend reinvestment.

Period	SOPH	MTLS
1 month	+13.11%	+12.71%
3 months	+11.07%	+34.62%
6 months	+20.00%	+18.12%
1 year	+75.24%	+20.04%
5 years(CAGR)	-20.21%	-22.71%
10 years(CAGR)	N/A	-0.61%
Max(CAGR)	-20.21%	-4.50%

Winner

SOPH

+13.11%

MTLS

+12.71%

SOPH

+11.07%

Winner

MTLS

+34.62%

Winner

SOPH

+20.00%

MTLS

+18.12%

Winner

SOPH

+75.24%

MTLS

+20.04%

5Y(CAGR)

Winner

SOPH

-20.21%

MTLS

-22.71%

10Y(CAGR)

SOPH

N/A

MTLS

-0.61%

Max(CAGR)

SOPH

-20.21%

Winner

MTLS

-4.50%

SOPH vs MTLS - Annual Returns (2014 - 2026)

Returns include dividend reinvestment.

Year	SOPH	MTLS
2026	+18.20%	+22.02%
2025	+46.39%	-21.72%
2024	-36.44%	+11.92%
2023	+109.33%	-23.93%
2022	-85.89%	-64.07%
2021	-15.87%	-56.24%
2020	N/A	+191.30%
2019	N/A	-8.72%
2018	N/A	+61.53%
2017	N/A	+65.49%
2016	N/A	+9.09%
2015	N/A	-26.23%
2014	N/A	-17.58%

SOPH vs MTLS Drawdown Comparison

The maximum drawdown for SOPH was -91.35%, occurring on Nov 9, 2022. This drawdown has not yet recovered.

The maximum drawdown for MTLS was -94.84%, occurring on Apr 7, 2025. This drawdown has not yet recovered.

The current SOPH drawdown is -72.08%. The current MTLS drawdown is -91.75%.

Rank	SOPH	MTLS
#1	-91.35% Aug 31, 2021 - Nov 9, 2022	-94.84% Feb 9, 2021 - Apr 7, 2025
#2	-10.71% Jul 26, 2021 - Aug 3, 2021	-62.79% Jul 7, 2014 - Jul 25, 2017
#3	-7.38% Aug 6, 2021 - Aug 23, 2021	-44.89% Jan 9, 2019 - Apr 29, 2020
#4	-2.69% Aug 23, 2021 - Aug 26, 2021	-37.29% Oct 14, 2020 - Dec 22, 2020
#5	-2.06% Aug 3, 2021 - Aug 6, 2021	-30.33% Oct 16, 2017 - Dec 18, 2018
#6	-0.94% Aug 26, 2021 - Aug 30, 2021	-28.50% Sep 2, 2020 - Oct 9, 2020
#7	N/A	-23.77% Jun 10, 2020 - Jul 21, 2020
#8	N/A	-21.51% Jul 21, 2020 - Aug 21, 2020
#9	N/A	-18.53% Jul 25, 2017 - Oct 5, 2017
#10	N/A	-15.91% Apr 29, 2020 - May 20, 2020
#11	N/A	-15.36% Dec 23, 2020 - Jan 6, 2021
#12	N/A	-12.51% Jan 19, 2021 - Feb 8, 2021
#13	N/A	-8.93% Jan 8, 2021 - Jan 14, 2021
#14	N/A	-8.63% Jan 14, 2021 - Jan 19, 2021
#15	N/A	-7.28% May 26, 2020 - Jun 1, 2020