SNTI vs MLSS

Comparison between Senti Biosciences Inc (SNTI, Company) and Milestone Scientific Inc (MLSS, Company).

Both SNTI and MLSS are from the Healthcare sector.

5-Year PerformanceMLSS has outperformed SNTI, delivering a return of -30.3% compared to -60.4%

SNTI vs MLSS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SNTI(COMPANY)	MLSS(COMPANY)
Market Cap	$30M	$31M
Max Drawdown	99.25%	98.77%
Sharpe Ratio	-0.80	-0.69
5Y Beta	1.47	0.97
Industry	Biotechnology	Medical Instruments & Supplies
P/E Ratio	-0.52	-6.77
Forward P/E	N/A	18.21
PEG Ratio	-0.94	0.00
5Y EPS CAGR	N/A	-11.33%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	N/A	-5.86%
P/S Ratio	786.90	3.82
P/B Ratio	11.00	16.01

Market Cap

SNTI

$30M

Winner

MLSS

$31M

Max Drawdown

SNTI

99.25%

Winner

MLSS

98.77%

Sharpe Ratio

SNTI

-0.80

Winner

MLSS

-0.69

5Y Beta

SNTI

1.47

Winner

MLSS

0.97

Industry

SNTI

Biotechnology

MLSS

Medical Instruments & Supplies

P/E Ratio

SNTI

-0.52

Winner

MLSS

-6.77

Forward P/E

SNTI

N/A

MLSS

18.21

PEG Ratio

Winner

SNTI

-0.94

MLSS

0.00

5Y EPS CAGR

SNTI

N/A

MLSS

-11.33%

Debt to Equity

SNTI

0.00%

MLSS

0.00%

Free Cash Flow Yield

SNTI

N/A

MLSS

-5.86%

P/S Ratio

SNTI

786.90

Winner

MLSS

3.82

P/B Ratio

Winner

SNTI

11.00

MLSS

16.01

SNTI vs MLSS - Historical Returns

Returns include dividend reinvestment.

Period	SNTI	MLSS
1 month	-4.24%	+3.46%
3 months	-1.45%	+23.00%
6 months	-20.07%	-3.68%
1 year	-66.18%	-61.59%
5 years(CAGR)	-60.44%	-30.34%
10 years(CAGR)	N/A	-19.00%
Max(CAGR)	-60.04%	-7.65%

SNTI

-4.24%

Winner

MLSS

+3.46%

SNTI

-1.45%

Winner

MLSS

+23.00%

SNTI

-20.07%

Winner

MLSS

-3.68%

SNTI

-66.18%

Winner

MLSS

-61.59%

5Y(CAGR)

SNTI

-60.44%

Winner

MLSS

-30.34%

10Y(CAGR)

SNTI

N/A

MLSS

-19.00%

Max(CAGR)

SNTI

-60.04%

Winner

MLSS

-7.65%

SNTI vs MLSS - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	SNTI	MLSS
2026	-12.07%	+14.69%
2025	-72.70%	-70.96%
2024	-46.90%	+45.45%
2023	-55.41%	+41.95%
2022	-85.70%	-77.88%
2021	-1.20%	-10.82%
2020	N/A	+50.35%
2019	N/A	+308.82%
2018	N/A	-70.13%
2017	N/A	-9.15%
2016	N/A	-40.68%
2015	N/A	+0.00%
2014	N/A	+35.29%
2013	N/A	+3.03%
2012	N/A	+113.24%
2011	N/A	-65.71%
2010	N/A	-40.70%
2009	N/A	+236.36%
2008	N/A	-82.17%
2007	N/A	+51.79%
2006	N/A	-17.86%
2005	N/A	-24.86%
2004	N/A	-53.65%
2003	N/A	+267.86%
2002	N/A	-55.88%
2001	N/A	-64.80%
2000	N/A	+50.00%
1999	N/A	-13.33%

SNTI vs MLSS Drawdown Comparison

The maximum drawdown for SNTI was -99.25%, occurring on Mar 30, 2026. This drawdown has not yet recovered.

The maximum drawdown for MLSS was -98.77%, occurring on Nov 19, 2008. This drawdown has not yet recovered.

The current SNTI drawdown is -99.06%. The current MLSS drawdown is -97.93%.

Rank	SNTI	MLSS
#1	-99.25% Nov 2, 2021 - Mar 30, 2026	-98.77% Mar 2, 2000 - Nov 19, 2008
#2	-3.88% May 27, 2021 - Oct 26, 2021	-31.25% Nov 8, 1999 - Jan 7, 2000
#3	-0.30% Oct 26, 2021 - Oct 29, 2021	-25.00% Feb 14, 2000 - Feb 29, 2000
#4	N/A	-20.00% Jan 10, 2000 - Jan 24, 2000
#5	N/A	-19.44% Feb 1, 2000 - Feb 7, 2000
#6	N/A	-19.05% Feb 8, 2000 - Feb 14, 2000
#7	N/A	-11.11% Jan 27, 2000 - Jan 31, 2000
#8	N/A	-6.67% Nov 1, 1999 - Nov 8, 1999