SMLR vs ISSC

Comparison between Semler Scientific Inc (SMLR, Company) and Innovative Solutions And Support Inc (ISSC, Company).

SMLR is from the Healthcare sector, while ISSC is from the Industrials sector.

5-Year PerformanceISSC has outperformed SMLR, delivering a return of +22.3% compared to -25.5%

SMLR vs ISSC - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SMLR(COMPANY)	ISSC(COMPANY)
Market Cap	$308M	$306M
Max Drawdown	89.86%	92.89%
Sharpe Ratio	-0.60	0.75
5Y Beta	N/A	1.42
Industry	Medical Devices	Aerospace & Defense
P/E Ratio	8.76	19.89
Forward P/E	N/A	9.50
PEG Ratio	5.02	0.09
5Y EPS CAGR	-1.48%	N/A
Debt to Equity	4.35%	76.16%
Free Cash Flow Yield	-8.75%	4.31%

Market Cap

Winner

SMLR

$308M

ISSC

$306M

Max Drawdown

Winner

SMLR

89.86%

ISSC

92.89%

Sharpe Ratio

SMLR

-0.60

Winner

ISSC

0.75

5Y Beta

SMLR

N/A

ISSC

1.42

Industry

SMLR

Medical Devices

ISSC

Aerospace & Defense

P/E Ratio

Winner

SMLR

8.76

ISSC

19.89

Forward P/E

SMLR

N/A

ISSC

9.50

PEG Ratio

SMLR

5.02

Winner

ISSC

0.09

5Y EPS CAGR

SMLR

-1.48%

ISSC

N/A

Debt to Equity

Winner

SMLR

4.35%

ISSC

76.16%

Free Cash Flow Yield

SMLR

-8.75%

Winner

ISSC

4.31%

SMLR vs ISSC - Historical Returns

Returns include dividend reinvestment.

Period	SMLR	ISSC
1 month	+16.84%	+0.30%
3 months	-17.59%	-45.06%
6 months	-52.40%	-9.71%
1 year	-65.09%	+30.12%
5 years(CAGR)	-25.51%	+22.29%
10 years(CAGR)	+24.28%	+20.54%
Max(CAGR)	+9.39%	+6.66%

Winner

SMLR

+16.84%

ISSC

+0.30%

Winner

SMLR

-17.59%

ISSC

-45.06%

SMLR

-52.40%

Winner

ISSC

-9.71%

SMLR

-65.09%

Winner

ISSC

+30.12%

5Y(CAGR)

SMLR

-25.51%

Winner

ISSC

+22.29%

10Y(CAGR)

Winner

SMLR

+24.28%

ISSC

+20.54%

Max(CAGR)

Winner

SMLR

+9.39%

ISSC

+6.66%

SMLR vs ISSC - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	SMLR	ISSC
2026	+14.34%	-12.21%
2025	-72.00%	+119.21%
2024	+22.23%	+1.07%
2023	+39.89%	+5.31%
2022	-64.61%	+25.13%
2021	-0.14%	+4.13%
2020	+95.83%	+30.01%
2019	+37.14%	+166.67%
2018	+330.00%	-24.41%
2017	+451.72%	-15.52%
2016	-42.91%	+18.51%
2015	+30.61%	-15.08%
2014	-71.96%	-55.34%
2013	N/A	+108.29%
2012	N/A	+66.86%
2011	N/A	-41.69%
2010	N/A	+24.62%
2009	N/A	+16.20%
2008	N/A	-49.65%
2007	N/A	-41.70%
2006	N/A	+32.43%
2005	N/A	-42.38%
2004	N/A	+105.67%
2003	N/A	+158.19%
2002	N/A	-20.20%
2001	N/A	-53.28%
2000	N/A	+43.72%

SMLR vs ISSC Drawdown Comparison

The maximum drawdown for SMLR was -89.86%, occurring on Dec 30, 2025. This drawdown has not yet recovered.

The maximum drawdown for ISSC was -89.05%, occurring on Jan 27, 2009. Recovery took 4465 trading sessions.

The current SMLR drawdown is -86.45%. The current ISSC drawdown is -46.14%.

Rank	SMLR	ISSC
#1	-89.86% Oct 29, 2021 - Dec 30, 2025	-89.05% Apr 26, 2007 - Jan 23, 2025
#2	-80.57% Feb 26, 2014 - Nov 1, 2017	-78.02% Oct 23, 2000 - May 18, 2004
#3	-44.50% Feb 24, 2020 - Aug 3, 2020	-57.83% Aug 13, 2025 - Jan 12, 2026
#4	-28.84% Oct 3, 2018 - Jan 22, 2019	-52.98% Feb 5, 2025 - Jun 4, 2025
#5	-27.60% Jul 31, 2019 - Feb 19, 2020	-52.61% May 11, 2005 - Mar 19, 2007
#6	-19.76% Mar 2, 2021 - Jul 7, 2021	-48.66% Mar 10, 2026 - May 19, 2026
#7	-16.61% Aug 3, 2020 - Oct 22, 2020	-27.69% Aug 26, 2004 - Nov 23, 2004
#8	-16.54% Jul 9, 2021 - Sep 27, 2021	-20.81% Dec 15, 2004 - May 6, 2005
#9	-13.33% Dec 18, 2017 - Feb 28, 2018	-19.15% Jan 14, 2026 - Feb 18, 2026
#10	-12.95% Apr 29, 2019 - Jul 17, 2019	-14.82% Jul 7, 2004 - Aug 16, 2004
#11	-12.77% Dec 31, 2020 - Feb 3, 2021	-11.06% Jun 9, 2004 - Jul 7, 2004
#12	-9.79% Mar 6, 2018 - May 1, 2018	-11.05% May 18, 2004 - May 28, 2004
#13	-9.34% Nov 2, 2017 - Dec 6, 2017	-10.84% Oct 3, 2000 - Oct 23, 2000
#14	-8.71% Aug 8, 2018 - Aug 27, 2018	-10.06% Mar 4, 2026 - Mar 10, 2026
#15	-8.06% Oct 22, 2020 - Nov 5, 2020	-9.38% Sep 1, 2000 - Sep 21, 2000