SMLR vs EPRX

Comparison between Semler Scientific Inc (SMLR, Company) and Eupraxia Pharmaceuticals Inc (EPRX, Company).

Both SMLR and EPRX are from the Healthcare sector.

5-Year PerformanceEPRX has outperformed SMLR, delivering a return of +17.2% compared to -25.5%

SMLR vs EPRX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SMLR(COMPANY)	EPRX(COMPANY)
Market Cap	$308M	$307M
Max Drawdown	89.86%	69.46%
Sharpe Ratio	-0.60	0.91
5Y Beta	N/A	0.81
Industry	Medical Devices	Biotechnology
P/E Ratio	8.76	-7.97
PEG Ratio	5.02	-2.10
5Y EPS CAGR	-1.48%	N/A
Debt to Equity	4.35%	0.00%
Free Cash Flow Yield	-8.75%	-9.29%
P/B Ratio	N/A	3.58

Market Cap

Winner

SMLR

$308M

EPRX

$307M

Max Drawdown

SMLR

89.86%

Winner

EPRX

69.46%

Sharpe Ratio

SMLR

-0.60

Winner

EPRX

0.91

5Y Beta

SMLR

N/A

EPRX

0.81

Industry

SMLR

Medical Devices

EPRX

Biotechnology

P/E Ratio

SMLR

8.76

Winner

EPRX

-7.97

PEG Ratio

SMLR

5.02

Winner

EPRX

-2.10

5Y EPS CAGR

SMLR

-1.48%

EPRX

N/A

Debt to Equity

SMLR

4.35%

Winner

EPRX

0.00%

Free Cash Flow Yield

Winner

SMLR

-8.75%

EPRX

-9.29%

P/B Ratio

SMLR

N/A

EPRX

3.58

SMLR vs EPRX - Historical Returns

Returns include dividend reinvestment.

Period	SMLR	EPRX
1 month	+16.84%	-20.63%
3 months	-17.59%	-19.47%
6 months	-52.40%	-3.67%
1 year	-65.09%	+55.47%
5 years(CAGR)	-25.51%	+17.25%
10 years(CAGR)	+24.28%	N/A
Max(CAGR)	+9.39%	+17.25%

Winner

SMLR

+16.84%

EPRX

-20.63%

Winner

SMLR

-17.59%

EPRX

-19.47%

SMLR

-52.40%

Winner

EPRX

-3.67%

SMLR

-65.09%

Winner

EPRX

+55.47%

5Y(CAGR)

SMLR

-25.51%

Winner

EPRX

+17.25%

10Y(CAGR)

SMLR

+24.28%

EPRX

N/A

Max(CAGR)

SMLR

+9.39%

Winner

EPRX

+17.25%

SMLR vs EPRX - Annual Returns (2014 - 2026)

Returns include dividend reinvestment.

Year	SMLR	EPRX
2026	+14.34%	-20.21%
2025	-72.00%	+141.21%
2024	+22.23%	-23.82%
2023	+39.89%	+54.69%
2022	-64.61%	+16.96%
2021	-0.14%	-17.53%
2020	+95.83%	N/A
2019	+37.14%	N/A
2018	+330.00%	N/A
2017	+451.72%	N/A
2016	-42.91%	N/A
2015	+30.61%	N/A
2014	-71.96%	N/A

SMLR vs EPRX Drawdown Comparison

The maximum drawdown for SMLR was -89.86%, occurring on Dec 30, 2025. This drawdown has not yet recovered.

The maximum drawdown for EPRX was -69.46%, occurring on Jun 27, 2022. Recovery took 314 trading sessions.

The current SMLR drawdown is -86.45%. The current EPRX drawdown is -33.41%.

Rank	SMLR	EPRX
#1	-89.86% Oct 29, 2021 - Dec 30, 2025	-69.46% Aug 3, 2021 - Oct 31, 2022
#2	-80.57% Feb 26, 2014 - Nov 1, 2017	-66.06% Jul 5, 2023 - Dec 22, 2025
#3	-44.50% Feb 24, 2020 - Aug 3, 2020	-34.73% Feb 3, 2026 - Jun 10, 2026
#4	-28.84% Oct 3, 2018 - Jan 22, 2019	-18.73% Nov 3, 2022 - Apr 13, 2023
#5	-27.60% Jul 31, 2019 - Feb 19, 2020	-12.74% Jan 21, 2026 - Feb 3, 2026
#6	-19.76% Mar 2, 2021 - Jul 7, 2021	-7.40% May 23, 2023 - Jun 13, 2023
#7	-16.61% Aug 3, 2020 - Oct 22, 2020	-6.90% Jun 13, 2023 - Jun 29, 2023
#8	-16.54% Jul 9, 2021 - Sep 27, 2021	-6.73% Dec 29, 2025 - Jan 8, 2026
#9	-13.33% Dec 18, 2017 - Feb 28, 2018	-6.08% Apr 27, 2023 - May 12, 2023
#10	-12.95% Apr 29, 2019 - Jul 17, 2019	-5.50% Apr 17, 2023 - Apr 27, 2023
#11	-12.77% Dec 31, 2020 - Feb 3, 2021	-5.47% Jan 8, 2026 - Jan 15, 2026
#12	-9.79% Mar 6, 2018 - May 1, 2018	-4.35% May 12, 2023 - May 23, 2023
#13	-9.34% Nov 2, 2017 - Dec 6, 2017	-0.23% Jan 15, 2026 - Jan 20, 2026
#14	-8.71% Aug 8, 2018 - Aug 27, 2018	N/A
#15	-8.06% Oct 22, 2020 - Nov 5, 2020	N/A

Correlation

Correlation between SMLR and EPRX is -0.36 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.36

-101