SION vs TPB

Comparison between Sionna Therapeutics Inc (SION, Company) and Turning Point Brands Inc (TPB, Company).

SION is from the Healthcare sector, while TPB is from the Consumer Defensive sector.

SION vs TPB - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SION(COMPANY)	TPB(COMPANY)
Market Cap	$1.53B	$1.54B
Max Drawdown	69.36%	72.85%
Sharpe Ratio	1.19	0.38
5Y Beta	0.96	0.60
Industry	Biotechnology	Tobacco
P/E Ratio	-17.76	23.69
Forward P/E	N/A	57.80
PEG Ratio	N/A	0.93
Dividend Yield	N/A	0.38%
5Y Dividends CAGR	N/A	13.14%
5Y EPS CAGR	N/A	43.77%
Debt to Equity	0.00%	76.24%
Free Cash Flow Yield	-4.70%	0.08%
P/S Ratio	N/A	3.27
P/B Ratio	5.33	4.29

Market Cap

SION

$1.53B

Winner

TPB

$1.54B

Max Drawdown

Winner

SION

69.36%

TPB

72.85%

Sharpe Ratio

Winner

SION

1.19

TPB

0.38

5Y Beta

SION

0.96

Winner

TPB

0.60

Industry

SION

Biotechnology

TPB

Tobacco

P/E Ratio

Winner

SION

-17.76

TPB

23.69

Forward P/E

SION

N/A

TPB

57.80

PEG Ratio

SION

N/A

TPB

0.93

Dividend Yield

SION

N/A

TPB

0.38%

5Y Dividends CAGR

SION

N/A

TPB

13.14%

5Y EPS CAGR

SION

N/A

TPB

43.77%

Debt to Equity

Winner

SION

0.00%

TPB

76.24%

Free Cash Flow Yield

SION

-4.70%

Winner

TPB

0.08%

P/S Ratio

SION

N/A

TPB

3.27

P/B Ratio

SION

5.33

Winner

TPB

4.29

SION vs TPB - Historical Returns

Returns include dividend reinvestment.

Period	SION	TPB
1 month	-12.26%	-11.20%
3 months	-2.07%	-7.12%
6 months	-16.02%	-21.52%
1 year	+111.42%	+9.59%
5 years(CAGR)	N/A	+13.71%
10 years(CAGR)	N/A	+27.47%
Max(CAGR)	+31.02%	+23.86%

SION

-12.26%

Winner

TPB

-11.20%

Winner

SION

-2.07%

TPB

-7.12%

Winner

SION

-16.02%

TPB

-21.52%

Winner

SION

+111.42%

TPB

+9.59%

5Y(CAGR)

SION

N/A

TPB

+13.71%

10Y(CAGR)

SION

N/A

TPB

+27.47%

Max(CAGR)

Winner

SION

+31.02%

TPB

+23.86%

SION vs TPB - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	SION	TPB
2026	-8.39%	-25.05%
2025	+64.56%	+79.40%
2024	N/A	+132.30%
2023	N/A	+22.88%
2022	N/A	-40.89%
2021	N/A	-11.74%
2020	N/A	+60.31%
2019	N/A	+4.72%
2018	N/A	+31.62%
2017	N/A	+69.97%
2016	N/A	+21.05%

SION vs TPB Drawdown Comparison

The maximum drawdown for SION was -69.36%, occurring on Apr 10, 2025. Recovery took 137 trading sessions.

The maximum drawdown for TPB was -72.75%, occurring on Mar 18, 2020. Recovery took 392 trading sessions.

The current SION drawdown is -21.83%. The current TPB drawdown is -42.21%.

Rank	SION	TPB
#1	-69.36% Feb 7, 2025 - Aug 26, 2025	-72.75% Jul 18, 2019 - Feb 5, 2021
#2	-27.07% May 11, 2026 - Jun 8, 2026	-66.44% Feb 12, 2021 - Nov 14, 2024
#3	-23.74% Feb 3, 2026 - Apr 15, 2026	-50.58% Feb 25, 2026 - Apr 21, 2026
#4	-19.06% Oct 21, 2025 - Nov 21, 2025	-39.36% May 17, 2016 - Aug 15, 2016
#5	-18.12% Nov 24, 2025 - Feb 3, 2026	-37.90% Oct 8, 2018 - Mar 5, 2019
#6	-17.26% Apr 16, 2026 - May 11, 2026	-24.78% Sep 8, 2016 - Apr 10, 2017
#7	-15.94% Aug 28, 2025 - Sep 22, 2025	-22.38% Mar 3, 2025 - May 7, 2025
#8	-5.53% Oct 3, 2025 - Oct 15, 2025	-17.32% Sep 23, 2025 - Nov 7, 2025
#9	-3.56% Sep 29, 2025 - Oct 3, 2025	-17.29% Mar 18, 2019 - May 1, 2019
#10	-2.41% Oct 16, 2025 - Oct 21, 2025	-16.98% Oct 17, 2017 - Dec 27, 2017
#11	-0.36% Aug 26, 2025 - Aug 28, 2025	-15.63% Aug 2, 2018 - Sep 5, 2018
#12	N/A	-15.19% Apr 24, 2017 - Aug 30, 2017
#13	N/A	-14.12% Dec 6, 2024 - Feb 6, 2025
#14	N/A	-14.05% Aug 15, 2016 - Aug 24, 2016
#15	N/A	-13.77% Jan 12, 2018 - May 10, 2018