SION vs PVLA
Comparison between Sionna Therapeutics Inc (SION, Company) and Palvella Therapeutics Inc (PVLA, Company).
Both SION and PVLA are from the Healthcare sector.
SION vs PVLA - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
SION
$2.03B
Winner
PVLA
$2.04B
Max Drawdown
SION
69.36%
Winner
PVLA
31.48%
Sharpe Ratio
SION
1.42
Winner
PVLA
2.00
5Y Beta
Winner
SION
0.91
PVLA
1.03
Industry
SION
Biotechnology
PVLA
Biotechnology
P/E Ratio
SION
-23.49
Winner
PVLA
-35.47
Debt to Equity
SION
0.00%
PVLA
0.00%
Free Cash Flow Yield
SION
-3.55%
Winner
PVLA
-1.43%
P/B Ratio
Winner
SION
7.37
PVLA
8.89
SION vs PVLA - Historical Returns
Returns include dividend reinvestment.
1M
SION
+10.51%
Winner
PVLA
+20.66%
3M
Winner
SION
+14.89%
PVLA
+12.72%
6M
SION
+3.96%
Winner
PVLA
+67.88%
1Y
SION
+122.86%
Winner
PVLA
+272.64%
Max(CAGR)
SION
+47.67%
Winner
PVLA
+352.15%
SION vs PVLA - Annual Returns (2024 - 2026)
Returns include dividend reinvestment.
| Year | SION | PVLA |
|---|---|---|
| 2026 | +12.37% | +42.81% |
| 2025 | +64.56% | +772.25% |
| 2024 | N/A | -6.47% |
SION vs PVLA Drawdown Comparison
The maximum drawdown for SION was -69.36%, occurring on Apr 10, 2025. Recovery took 137 trading sessions.
The maximum drawdown for PVLA was -31.48%, occurring on Apr 10, 2025. Recovery took 87 trading sessions.
The current SION drawdown is -10.83%. The current PVLA drawdown is -8.93%.
| Rank | SION | PVLA |
|---|---|---|
| #1 | -69.36% Feb 7, 2025 - Aug 26, 2025 | -31.48% Mar 12, 2025 - Jul 17, 2025 |
| #2 | -27.07% May 11, 2026 - Jul 17, 2026 | -31.11% Feb 26, 2026 - Jun 29, 2026 |
| #3 | -23.74% Feb 3, 2026 - Apr 15, 2026 | -29.93% Dec 22, 2025 - Feb 24, 2026 |
| #4 | -19.06% Oct 21, 2025 - Nov 21, 2025 | -21.04% Jul 17, 2026 - Jul 20, 2026 |
| #5 | -18.12% Nov 24, 2025 - Feb 3, 2026 | -15.35% Jan 6, 2025 - Feb 5, 2025 |
| #6 | -17.26% Apr 16, 2026 - May 11, 2026 | -13.44% Nov 28, 2025 - Dec 22, 2025 |
| #7 | -15.94% Aug 28, 2025 - Sep 22, 2025 | -10.71% Jun 29, 2026 - Jul 17, 2026 |
| #8 | -10.83% Jul 17, 2026 - Jul 23, 2026 | -10.43% Feb 18, 2025 - Mar 5, 2025 |
| #9 | -5.53% Oct 3, 2025 - Oct 15, 2025 | -9.32% Oct 20, 2025 - Oct 30, 2025 |
| #10 | -3.56% Sep 29, 2025 - Oct 3, 2025 | -9.31% Dec 17, 2024 - Jan 3, 2025 |
| #11 | -2.41% Oct 16, 2025 - Oct 21, 2025 | -9.12% Aug 27, 2025 - Sep 9, 2025 |
| #12 | -0.36% Aug 26, 2025 - Aug 28, 2025 | -8.74% Sep 10, 2025 - Sep 29, 2025 |
| #13 | N/A | -8.33% Jul 28, 2025 - Aug 8, 2025 |
| #14 | N/A | -6.61% Oct 8, 2025 - Oct 13, 2025 |
| #15 | N/A | -6.16% Aug 22, 2025 - Aug 26, 2025 |
Correlation
Correlation between SION and PVLA is 0.91 which considered as a very strong positive correlation - the stocks move almost identically together.
0.91
-101
Select Stocks to Compare
Popular: SION vs SPYPVLA vs SPY
More Comparisons
Compare with similar stocks