SERA vs LIXT

Comparison between Sera Prognostics Inc Class A (SERA, Company) and Lixte Biotechnology Holdings Inc (LIXT, Company).

Both SERA and LIXT are from the Healthcare sector.

5-Year PerformanceLIXT has outperformed SERA, delivering a return of -23.7% compared to -31.4%

SERA vs LIXT - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SERA(COMPANY)	LIXT(COMPANY)
Market Cap	$88M	$89M
Max Drawdown	91.10%	99.12%
Sharpe Ratio	0.48	2.11
5Y Beta	1.02	0.62
Industry	Medical Devices	Biotechnology
P/E Ratio	-2.56	-6.94
PEG Ratio	N/A	0.00
5Y EPS CAGR	N/A	24.68%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-31.35%	-4.90%
P/S Ratio	1202.24	20.35
P/B Ratio	1.07	16.61

Market Cap

SERA

$88M

Winner

LIXT

$89M

Max Drawdown

Winner

SERA

91.10%

LIXT

99.12%

Sharpe Ratio

SERA

0.48

Winner

LIXT

2.11

5Y Beta

SERA

1.02

Winner

LIXT

0.62

Industry

SERA

Medical Devices

LIXT

Biotechnology

P/E Ratio

SERA

-2.56

Winner

LIXT

-6.94

PEG Ratio

SERA

N/A

LIXT

0.00

5Y EPS CAGR

SERA

N/A

LIXT

24.68%

Debt to Equity

SERA

0.00%

LIXT

0.00%

Free Cash Flow Yield

SERA

-31.35%

Winner

LIXT

-4.90%

P/S Ratio

SERA

1202.24

Winner

LIXT

20.35

P/B Ratio

Winner

SERA

1.07

LIXT

16.61

SERA vs LIXT - Historical Returns

Returns include dividend reinvestment.

Period	SERA	LIXT
1 month	-10.63%	+27.21%
3 months	+1.65%	+181.20%
6 months	-48.61%	+79.38%
1 year	-1.07%	+849.72%
5 years(CAGR)	-31.41%	-23.69%
10 years(CAGR)	N/A	-4.62%
Max(CAGR)	-31.41%	-6.17%

SERA

-10.63%

Winner

LIXT

+27.21%

SERA

+1.65%

Winner

LIXT

+181.20%

SERA

-48.61%

Winner

LIXT

+79.38%

SERA

-1.07%

Winner

LIXT

+849.72%

5Y(CAGR)

SERA

-31.41%

Winner

LIXT

-23.69%

10Y(CAGR)

SERA

N/A

LIXT

-4.62%

Max(CAGR)

SERA

-31.41%

Winner

LIXT

-6.17%

SERA vs LIXT - Annual Returns (2010 - 2026)

Returns include dividend reinvestment.

Year	SERA	LIXT
2026	-38.33%	+94.79%
2025	-64.59%	+77.03%
2024	+36.35%	-11.37%
2023	+356.49%	-53.68%
2022	-83.57%	-60.85%
2021	-42.27%	-62.93%
2020	N/A	-37.84%
2019	N/A	-27.66%
2018	N/A	+447.35%
2017	N/A	+37.50%
2016	N/A	-68.87%
2015	N/A	+22.92%
2014	N/A	+20.00%
2013	N/A	-48.00%
2012	N/A	-50.00%
2011	N/A	-20.63%
2010	N/A	+80.00%

SERA vs LIXT Drawdown Comparison

The maximum drawdown for SERA was -91.10%, occurring on Dec 28, 2022. This drawdown has not yet recovered.

The maximum drawdown for LIXT was -99.12%, occurring on Jun 27, 2025. This drawdown has not yet recovered.

The current SERA drawdown is -85.81%. The current LIXT drawdown is -90.77%.

Rank	SERA	LIXT
#1	-91.10% Aug 9, 2021 - Dec 28, 2022	-99.12% Aug 26, 2019 - Jun 27, 2025
#2	-23.11% Jul 15, 2021 - Aug 2, 2021	-90.82% Apr 4, 2011 - Aug 22, 2018
#3	-8.00% Aug 2, 2021 - Aug 5, 2021	-88.00% May 19, 2010 - Sep 20, 2010
#4	N/A	-49.00% Aug 22, 2018 - Oct 12, 2018
#5	N/A	-46.15% Nov 1, 2018 - Aug 22, 2019
#6	N/A	-25.93% Oct 12, 2018 - Oct 18, 2018
#7	N/A	-20.00% Feb 14, 2011 - Mar 17, 2011
#8	N/A	-18.75% Oct 18, 2018 - Nov 1, 2018
#9	N/A	-2.26% Aug 22, 2019 - Aug 26, 2019