SEPN vs GSL

Comparison between Septerna Inc (SEPN, Company) and Global Ship Lease Inc - Class A (GSL, Company).

SEPN is from the Healthcare sector, while GSL is from the Industrials sector.

SEPN vs GSL - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SEPN(COMPANY)	GSL(COMPANY)
Market Cap	$1.34B	$1.34B
Max Drawdown	81.47%	95.58%
Sharpe Ratio	2.08	1.74
5Y Beta	1.30	0.83
Industry	Biotechnology	Marine Shipping
P/E Ratio	-36.95	3.41
Forward P/E	107.53	3.11
PEG Ratio	N/A	0.87
Dividend Yield	N/A	6.33%
5Y Dividends CAGR	N/A	63.54%
5Y EPS CAGR	N/A	35.09%
Debt to Equity	0.00%	34.81%
Free Cash Flow Yield	7.99%	30.09%
P/S Ratio	18.84	1.73
P/B Ratio	3.59	0.70

Market Cap

SEPN

$1.34B

Winner

GSL

$1.34B

Max Drawdown

Winner

SEPN

81.47%

GSL

95.58%

Sharpe Ratio

Winner

SEPN

2.08

GSL

1.74

5Y Beta

SEPN

1.30

Winner

GSL

0.83

Industry

SEPN

Biotechnology

GSL

Marine Shipping

P/E Ratio

Winner

SEPN

-36.95

GSL

3.41

Forward P/E

SEPN

107.53

Winner

GSL

3.11

PEG Ratio

SEPN

N/A

GSL

0.87

Dividend Yield

SEPN

N/A

GSL

6.33%

5Y Dividends CAGR

SEPN

N/A

GSL

63.54%

5Y EPS CAGR

SEPN

N/A

GSL

35.09%

Debt to Equity

Winner

SEPN

0.00%

GSL

34.81%

Free Cash Flow Yield

SEPN

7.99%

Winner

GSL

30.09%

P/S Ratio

SEPN

18.84

Winner

GSL

1.73

P/B Ratio

SEPN

3.59

Winner

GSL

0.70

SEPN vs GSL - Historical Returns

Returns include dividend reinvestment.

Period	SEPN	GSL
1 month	+29.09%	-6.61%
3 months	+13.40%	+0.61%
6 months	+16.41%	+8.83%
1 year	+196.10%	+61.01%
5 years(CAGR)	N/A	+28.02%
10 years(CAGR)	N/A	+15.56%
Max(CAGR)	+26.26%	+0.75%

Winner

SEPN

+29.09%

GSL

-6.61%

Winner

SEPN

+13.40%

GSL

+0.61%

Winner

SEPN

+16.41%

GSL

+8.83%

Winner

SEPN

+196.10%

GSL

+61.01%

5Y(CAGR)

SEPN

N/A

GSL

+28.02%

10Y(CAGR)

SEPN

N/A

GSL

+15.56%

Max(CAGR)

Winner

SEPN

+26.26%

GSL

+0.75%

SEPN vs GSL - Annual Returns (2008 - 2026)

Returns include dividend reinvestment.

Year	SEPN	GSL
2026	+11.33%	+12.76%
2025	+30.59%	+66.82%
2024	+7.01%	+18.15%
2023	N/A	+29.34%
2022	N/A	-23.41%
2021	N/A	+102.68%
2020	N/A	+38.10%
2019	N/A	+58.79%
2018	N/A	-47.46%
2017	N/A	-25.16%
2016	N/A	-42.31%
2015	N/A	-41.54%
2014	N/A	-22.81%
2013	N/A	+95.77%
2012	N/A	+68.00%
2011	N/A	-64.16%
2010	N/A	+241.38%
2009	N/A	-55.55%
2008	N/A	-57.93%

SEPN vs GSL Drawdown Comparison

The maximum drawdown for SEPN was -81.47%, occurring on Apr 1, 2025. Recovery took 230 trading sessions.

The maximum drawdown for GSL was -95.25%, occurring on Mar 19, 2020. Recovery took 3774 trading sessions.

The current SEPN drawdown is -0.70%. The current GSL drawdown is -8.35%.

Rank	SEPN	GSL
#1	-81.47% Dec 23, 2024 - Nov 24, 2025	-95.25% Feb 23, 2011 - Feb 26, 2026
#2	-25.18% Feb 24, 2026 - May 28, 2026	-83.31% Aug 15, 2008 - Jan 19, 2011
#3	-21.10% Dec 19, 2025 - Feb 17, 2026	-12.51% Mar 2, 2026 - May 5, 2026
#4	-16.77% Dec 4, 2024 - Dec 23, 2024	-12.44% May 8, 2026 - May 29, 2026
#5	-16.19% Nov 7, 2024 - Dec 4, 2024	-4.83% Jan 21, 2011 - Jan 27, 2011
#6	-13.97% Nov 26, 2025 - Dec 19, 2025	-3.15% Jan 27, 2011 - Feb 9, 2011
#7	-10.63% Feb 17, 2026 - Feb 24, 2026	-1.13% Feb 14, 2011 - Feb 22, 2011
#8	-6.45% Oct 25, 2024 - Oct 31, 2024	-0.62% Jan 19, 2011 - Jan 21, 2011
#9	-4.76% Oct 31, 2024 - Nov 4, 2024	-0.19% May 6, 2026 - May 8, 2026
#10	-3.57% May 28, 2026 - Jun 4, 2026	N/A
#11	-3.45% Nov 4, 2024 - Nov 6, 2024	N/A
#12	-1.89% Nov 24, 2025 - Nov 26, 2025	N/A
#13	-0.70% Jun 4, 2026 - Jun 5, 2026	N/A