SEPN vs ECAT

Comparison between Septerna Inc (SEPN, Company) and BlackRock ESG Capital Allocation Term Trust (ECAT, Company).

SEPN is from the Healthcare sector, while ECAT is from the Financial Services sector.

SEPN vs ECAT - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SEPN(COMPANY)	ECAT(COMPANY)
Market Cap	$1.54B	$1.53B
Max Drawdown	81.47%	36.48%
Sharpe Ratio	1.78	0.85
5Y Beta	1.25	0.70
Industry	Biotechnology	Asset Management
P/E Ratio	-42.42	7.33
Forward P/E	107.53	N/A
Dividend Yield	N/A	21.50%
Debt to Equity	0.00%	0.02%
Free Cash Flow Yield	6.96%	22.50%
P/S Ratio	21.34	7.13
P/B Ratio	4.02	0.96

Market Cap

Winner

SEPN

$1.54B

ECAT

$1.53B

Max Drawdown

SEPN

81.47%

Winner

ECAT

36.48%

Sharpe Ratio

Winner

SEPN

1.78

ECAT

0.85

5Y Beta

SEPN

1.25

Winner

ECAT

0.70

Industry

SEPN

Biotechnology

ECAT

Asset Management

P/E Ratio

Winner

SEPN

-42.42

ECAT

7.33

Forward P/E

SEPN

107.53

ECAT

N/A

Dividend Yield

SEPN

N/A

ECAT

21.50%

Debt to Equity

Winner

SEPN

0.00%

ECAT

0.02%

Free Cash Flow Yield

SEPN

6.96%

Winner

ECAT

22.50%

P/S Ratio

SEPN

21.34

Winner

ECAT

7.13

P/B Ratio

SEPN

4.02

Winner

ECAT

0.96

SEPN vs ECAT - Historical Returns

Returns include dividend reinvestment.

Period	SEPN	ECAT
1 month	-8.48%	+0.33%
3 months	+34.04%	+10.89%
6 months	+29.90%	+8.91%
1 year	+147.38%	+15.26%
5 years(CAGR)	N/A	+9.02%
Max(CAGR)	+29.29%	+9.02%

SEPN

-8.48%

Winner

ECAT

+0.33%

Winner

SEPN

+34.04%

ECAT

+10.89%

Winner

SEPN

+29.90%

ECAT

+8.91%

Winner

SEPN

+147.38%

ECAT

+15.26%

5Y(CAGR)

SEPN

N/A

ECAT

+9.02%

Max(CAGR)

Winner

SEPN

+29.29%

ECAT

+9.02%

SEPN vs ECAT - Annual Returns (2021 - 2026)

Returns include dividend reinvestment.

Year	SEPN	ECAT
2026	+19.62%	+10.31%
2025	+30.59%	+16.70%
2024	+7.01%	+20.06%
2023	N/A	+31.13%
2022	N/A	-23.06%
2021	N/A	-6.24%

SEPN vs ECAT Drawdown Comparison

The maximum drawdown for SEPN was -81.47%, occurring on Apr 1, 2025. Recovery took 230 trading sessions.

The maximum drawdown for ECAT was -32.23%, occurring on Sep 29, 2022. Recovery took 582 trading sessions.

The current SEPN drawdown is -11.55%. The current ECAT drawdown is -3.26%.

Rank	SEPN	ECAT
#1	-81.47% Dec 23, 2024 - Nov 24, 2025	-32.23% Oct 1, 2021 - Jan 26, 2024
#2	-25.18% Feb 24, 2026 - May 28, 2026	-15.78% Feb 13, 2025 - May 13, 2025
#3	-21.10% Dec 19, 2025 - Feb 17, 2026	-11.72% Oct 28, 2025 - May 4, 2026
#4	-16.77% Dec 4, 2024 - Dec 23, 2024	-9.07% Jul 15, 2024 - Aug 23, 2024
#5	-16.60% Jul 9, 2026 - Jul 16, 2026	-6.87% Apr 1, 2024 - May 20, 2024
#6	-16.19% Nov 7, 2024 - Dec 4, 2024	-5.59% Dec 11, 2024 - Feb 13, 2025
#7	-13.97% Nov 26, 2025 - Dec 19, 2025	-4.57% Oct 14, 2024 - Nov 11, 2024
#8	-10.63% Feb 17, 2026 - Feb 24, 2026	-4.53% Aug 23, 2024 - Sep 27, 2024
#9	-10.36% Jun 26, 2026 - Jul 9, 2026	-4.24% Jun 2, 2026 - Jun 29, 2026
#10	-6.45% Oct 25, 2024 - Oct 31, 2024	-3.48% Mar 1, 2024 - Mar 27, 2024
#11	-5.55% Jun 23, 2026 - Jun 26, 2026	-3.26% Jul 15, 2026 - Jul 23, 2026
#12	-4.76% Oct 31, 2024 - Nov 4, 2024	-2.92% May 13, 2025 - Jun 2, 2025
#13	-3.65% Jun 18, 2026 - Jun 23, 2026	-2.72% Aug 13, 2025 - Sep 11, 2025
#14	-3.57% May 28, 2026 - Jun 4, 2026	-2.57% Nov 11, 2024 - Dec 2, 2024
#15	-3.45% Nov 4, 2024 - Nov 6, 2024	-2.50% Jan 29, 2024 - Feb 8, 2024