SCNI vs LYRA

Comparison between Scinai Immunotherapeutics Ltd (SCNI, Company) and Lyra Therapeutics Inc (LYRA, Company).

Both SCNI and LYRA are from the Healthcare sector.

5-Year PerformanceLYRA has outperformed SCNI, delivering a return of -73.1% compared to -75.6%

SCNI vs LYRA - Performance Comparison

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Key Characteristics

Financial metrics and valuation ratios

Metric	SCNI(COMPANY)	LYRA(COMPANY)
Market Cap	$1.13M	$1.03M
Max Drawdown	100.00%	99.96%
Sharpe Ratio	-1.39	-1.56
5Y Beta	0.86	N/A
Industry	Biotechnology	Biotechnology
P/E Ratio	-0.14	-0.03
Debt to Equity	0.00%	0.00%
P/S Ratio	1.00	N/A
P/B Ratio	0.56	N/A

Market Cap

Winner

SCNI

$1.13M

LYRA

$1.03M

Max Drawdown

SCNI

100.00%

Winner

LYRA

99.96%

Sharpe Ratio

Winner

SCNI

-1.39

LYRA

-1.56

5Y Beta

SCNI

0.86

LYRA

N/A

Industry

SCNI

Biotechnology

LYRA

Biotechnology

P/E Ratio

Winner

SCNI

-0.14

LYRA

-0.03

Debt to Equity

SCNI

0.00%

LYRA

0.00%

P/S Ratio

SCNI

1.00

LYRA

N/A

P/B Ratio

SCNI

0.56

LYRA

N/A

SCNI vs LYRA - Historical Returns

Returns include dividend reinvestment.

Period	SCNI	LYRA
1 month	-48.03%	-14.29%
3 months	-58.24%	+22.37%
6 months	-64.32%	-83.29%
1 year	-89.84%	-95.52%
5 years(CAGR)	-75.63%	-73.15%
10 years(CAGR)	-51.80%	N/A
Max(CAGR)	-48.45%	-69.69%

SCNI

-48.03%

Winner

LYRA

-14.29%

SCNI

-58.24%

Winner

LYRA

+22.37%

Winner

SCNI

-64.32%

LYRA

-83.29%

Winner

SCNI

-89.84%

LYRA

-95.52%

5Y(CAGR)

SCNI

-75.63%

Winner

LYRA

-73.15%

10Y(CAGR)

SCNI

-51.80%

LYRA

N/A

Max(CAGR)

Winner

SCNI

-48.45%

LYRA

-69.69%

SCNI vs LYRA - Annual Returns (2015 - 2026)

Returns include dividend reinvestment.

Year	SCNI	LYRA
2026	-65.59%	-81.01%
2025	-79.30%	-71.48%
2024	-45.14%	-96.03%
2023	-80.21%	+69.58%
2022	-87.35%	-32.91%
2021	-27.69%	-61.21%
2020	-72.16%	-38.58%
2019	+92.93%	N/A
2018	-13.59%	N/A
2017	+49.64%	N/A
2016	-10.98%	N/A
2015	-0.75%	N/A

SCNI vs LYRA Drawdown Comparison

The maximum drawdown for SCNI was -100.00%, occurring on Jun 26, 2026. This drawdown has not yet recovered.

The maximum drawdown for LYRA was -99.96%, occurring on Mar 23, 2026. This drawdown has not yet recovered.

The current SCNI drawdown is -100.00%. The current LYRA drawdown is -99.94%.

Rank	SCNI	LYRA
#1	-100.00% Jul 13, 2020 - Jun 26, 2026	-99.96% May 1, 2020 - Mar 23, 2026
#2	-61.86% Jul 24, 2017 - Jan 13, 2020	N/A
#3	-53.99% Jan 29, 2020 - Apr 29, 2020	N/A
#4	-39.76% Jun 26, 2015 - Feb 9, 2017	N/A
#5	-26.79% May 21, 2020 - Jun 23, 2020	N/A
#6	-15.54% Apr 4, 2017 - May 15, 2017	N/A
#7	-15.48% May 15, 2017 - Jun 19, 2017	N/A
#8	-13.90% Jun 26, 2017 - Jul 18, 2017	N/A
#9	-13.48% Feb 24, 2017 - Mar 30, 2017	N/A
#10	-13.12% Jan 13, 2020 - Jan 23, 2020	N/A
#11	-12.90% Apr 29, 2020 - May 4, 2020	N/A
#12	-12.77% May 6, 2020 - May 18, 2020	N/A
#13	-9.59% May 13, 2015 - May 19, 2015	N/A
#14	-9.55% May 19, 2015 - Jun 8, 2015	N/A
#15	-8.52% Jun 23, 2020 - Jul 6, 2020	N/A